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Ischemic Preconditioning of the Kidney

Bulletin of Experimental Biology and Medicine, 2021
The phenomenon of ischemic preconditioning was discovered in 1986 in experiments with the heart, and then it was observed in almost all organs, the kidneys included. This phenomenon is underlain by conditioning of the tissues with short ischemia/reperfusion cycles intended for subsequent exposure to pathological ischemia.
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Ischemic preconditioning

Current Opinion in Cardiology, 1997
It has been shown that repeated brief coronary occlusions increase myocardial resistance towards prolonged episodes of ischemia. This phenomenon, which renders the heart more tolerant to ischemia with subsequent limitation of infarct size, has been termed ischemic preconditioning and has been described in a variety of species.
E R, Schwarz, W S, Whyte, R A, Kloner
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MECHANISMS OF ISCHEMIC PRECONDITIONING

Shock, 1997
Ischemic preconditioning (IPC) refers to a phenomenon in which a tissue is rendered resistant to the deleterious effects of prolonged ischemia by previous exposure to brief periods of vascular occlusion. While the beneficial effects of IPC were first demonstrated in the myocardium, it is now clear that preconditioning protects postischemic skeletal ...
T, Ishida   +3 more
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Ischemic preconditioning in the brain

Current Opinion in Anaesthesiology, 2003
Brain ischemia is responsible for significant morbidity and mortality associated with cardiovascular surgery, and is the end result of multiple disease states, including cardiac arrest, stroke, and traumatic brain injury. Despite significant resources dedicated to developing neuroprotective strategies, little progress has been made in this regard ...
Daniel P, Davis, Piyush M, Patel
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Resveratrol and Ischemic Preconditioning in the Brain

Current Medicinal Chemistry, 2008
Cardiovascular pathologies in the French are not prevalent despite high dietary saturated fat consumption. This is commonly referred to as the "French Paradox" attributing its anti-lipidemic effects to moderate consumption of red wine. Resveratrol, a phytoalexin found in red wine, is currently the focus of intense research both in the cardiovascular ...
Raval, Ami P   +6 more
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Myocardial Ischemic Preconditioning

1994
Protection of ischemic myocardium through transient antecedent sublethal ischemia (myocardial ischemic preconditioning, IP) is a well established laboratory phenomenon which has caught the attention and imagination of clinicians and researchers throughout the world.
D M, Van Winkle, G L, Chien, R F, Davis
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Cardioprotection by Ischemic Preconditioning

1998
Murry et al. reduced infarct size in dogs through repetitive brief occlusions, preceding prolonged ischemia, and coined this phenomenon “ischemic preconditioning.”13 ATP breakdown was attenuated during the prolonged period of ischemia, possibly due to a decrease in contractile function prior to this ischemic period.
Jonge, R   +2 more
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Kidney ischemic preconditioning

Current Opinion in Nephrology and Hypertension, 2002
Ischemic injury to the kidney is associated with high morbidity and mortality. Improving the ability of the kidney to tolerate ischemic injury would have important implications. A significant amount of data now exists to suggest that there may be intrinsic mechanisms brought to bear by the kidney when exposed to a toxic or ischemic insult, which ...
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Remote ischemic preconditioning

Journal of Cardiovascular Medicine, 2013
Since cardiac surgery began, surgeons have aimed to find methods of minimizing myocardial injury resulting from ischemia and reperfusion. The concept of somehow conditioning the heart in order to attenuate ischemia and reperfusion-related injury has evolved in cardiovascular research over decades, from ischemic preconditioning and postconditioning to ...
Thielmann, Matthias Klaus   +6 more
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Autophagy is involved in the ischemic preconditioning

Neuroscience Letters, 2009
Autophagy is a key pathway for the clearance of damaged organelles. Ischemic preconditioning (IPC) and autophagy are enhanced by mild hypoxic insults, but the association between autophagy and IPC remains unclear. We investigated the existence and role of autophagy in IPC.
Hee-Kwon, Park   +7 more
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