Results 141 to 150 of about 1,317,566 (363)

Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/American Stroke Association.

Stroke, 2014
W. Kernan, B. Ovbiagele, Vice Chair, Henry R. Black, Dawn M. Bravata, M. Chimowitz, M. D. Ezekowitz, Margaret C. Fang, M. Fisher, K. Furie, Donald V. Heck, S. Claiborne, Clay Johnston, S. Kasner, S. Kittner, Pamela H. Mitchell, Michael W. Rich, D. Richardson, L. H. Schwamm, John A. Wilson   +19 more
semanticscholar   +1 more source

Targeting Multilayered Metabolic Networks in Brain Diseases: Emerging Perspectives on Nanodelivery Strategies

Advanced Science, EarlyView.
Brain diseases involve multilayered metabolic disruptions that reshape cellular interactions and microenvironments. This review outlines core metabolic features across disease states and presents emerging nanodelivery strategies as precision tools to reprogram pathological metabolism.
Jingyi Zhou, Chen Jiang
wiley   +1 more source

Predictors of recurrent ischemic stroke in a sample of Egyptian stroke patients

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery
Background Stroke is the third leading cause of mortality and a major cause of disability worldwide. Patients who experienced a first ischemic stroke are at high risk of recurrence with estimated risk of 8–14% within the first year.
Shaimaa Shaheen Mohammed, Nervana Mohammed Elfayoumy, Dina Hosny Mohammed, Amal H. Eissa, Anter Mothenna Abdullah Nasser, Amal S. Ashour   +5 more
doaj   +1 more source

Regulation of Neuroinflammation by Microglial DUBA‐IRAK1‐IKKβ Signaling Loop

Advanced Science, EarlyView.
The protein levels of deubiquitinating enzyme A (DUBA) are rapidly upregulated in microglia after activation of Toll‐like receptor 4 (TLR4). In turn, DUBA potentiates TLR4‐induced proinflammatory signal transduction in microglia by stabilizing interleukin‐1 receptor activated kinase 1 (IRAK1) through K48 deubiquitination.
Zhenhu Zhu, Zhongding Li, Kate Lykke Lambertsen, Zijun Cao, Meng Chen, Yanqi Xu, Bettina Hjelm Clausen, Keshuo Jin, Yiting Lu, Fuqi Mei, Xue Du, Kangmin Chen, Huiyuan Bai, Xian Su, Bincheng Zhou, Baohua Liu, Ran Li, Chaoqun Wang, Yuhua Li, Xiang Cai, Dirk Schlüter, Weihong Song, Xu Wang   +22 more
wiley   +1 more source

A randomized, double-blind, placebo-controlled trial of nimodipine in acute ischemic hemispheric stroke. [PDF]

, 1994
Markku Kaste, R Fogelholm, T. Erilä, Heikki Palomäki, Kari Murros, A Rissanen, Seppo Sarna   +6 more
openalex   +1 more source

Classification of Subtype of Acute Ischemic Stroke: Definitions for Use in a Multicenter Clinical Trial

Stroke, 1993
Timothy Carter, J. W. Tulloch, Mario Mendez, R. Tarrel, M. Nance, Scott R. Budlie, R. Shapiro, K. Ruggles, P. Gottschalk, Rodney W. Sorenson, D. Jacobson, John G. Schmidt   +11 more
semanticscholar   +1 more source

Adamts1 Exacerbates Post‐Myocardial Infarction Scar Formation via Mechanosensing of Integrin α8

Advanced Science, EarlyView.
Proposed mechanistic model of ADAMTS1‐ITGα8 mechanotransduction in post‐MI scar formation. Schematic illustration showing the mechanistic pathway by which endothelial cell (EC) derived Adamts1 regulates cardiac fibroblast activation through ITGα8‐mediated mechanotransduction following myocardial infarction (MI).
Chun‐Yan Kong, Zhen Guo, Yu‐Lan Ma, Ming‐Yu Wang, Hai‐Yang Ni, Pan Wang, Wen‐Jun Qiu, En‐Gui Wang, Zhou Li, Zheng Yang, Bo Shen, Qi‐Zhu Tang   +11 more
wiley   +1 more source

Status of Vitamin D and its Association with Stroke Risk Factors in Patients with Acute Ischemic Stroke in a Tertiary Care Hospital

, 1970
Lekhjung Thapa, Baburam Pokhrel, Asis Shrestha, Manohar Pradhan, Tirtha Raj Bhandari, Shakti Shrestha, Ramesh Sharma Poudel, Raju Poudel   +7 more
openalex   +2 more sources

Lactylation of HMGB1 at K177 Drives Nuclear Export of TIAR to Promote Hypoxia‐Induced Stress Granule Formation

Advanced Science, EarlyView.
This study uncovers a novel mechanism in which p300‑catalyzed lactylation of HMGB1 triggers nuclear export of the HMGB1‐TIAR complex, driving TIAR‐dependent SGs formation in the cytoplasm. Mass spectrometry and mutagenesis reveals that K177 lactylation is essential for this export and subsequent SGs formation.
Chengyu Li, Zhaojun Liu, Linjie Zhu, Gang Wu, Chen Fu, Hongmin Li, Tong He, Ming Shen, Honglin Liu   +8 more
wiley   +1 more source

High Waist to Hip Ratio as a Risk Factor for Ischemic Stroke Patients Admitted in a Tertiary Care Hospital

, 1970
Md Habib Khan, Sanjoy Kumar Chakraborty, Rajat Sanker Roy Biswas   +2 more
openalex   +2 more sources