Results 151 to 160 of about 324,233 (319)

Krüppel‐like factor 4 transcription factor in blood–brain barrier endothelial cells: A potential role in Alzheimer's disease

Animal Models and Experimental Medicine, EarlyView.
KLF4 (Krüppel‐like factor 4) plays a protective role in blood–brain barrier (BBB). KLF4 plays an ambiguous role in the central nervous system. KLF4 in the BBB endothelial cells could be a potential target for Alzheimer's disease. Abstract Alzheimer's disease is the most prevalent chronic neurodegenerative disorder worldwide, with no sufficient cure ...
Ziying Wei, Chunhua Liu, Jianyu Chen, Yuxiao Yao, Dajiang Qin   +4 more
wiley   +1 more source

Status of Vitamin D and its Association with Stroke Risk Factors in Patients with Acute Ischemic Stroke in a Tertiary Care Hospital

, 1970
Lekhjung Thapa, Baburam Pokhrel, Asis Shrestha, Manohar Pradhan, Tirtha Raj Bhandari, Shakti Shrestha, Ramesh Sharma Poudel, Raju Poudel   +7 more
openalex   +2 more sources

Intravenous Thrombolysis in Patients Taking Direct Oral Anticoagulation Treatment Before Stroke Onset: Results from the Safe Implementations of Treatments in Stroke International Stroke Registry

Annals of Neurology, EarlyView.
Objectives Intravenous thrombolysis (IVT) is contraindicated for acute ischemic stroke (AIS) patients taking direct oral anticoagulants (DOACs) within 48 hours before index stroke. Limited data exist on off‐label use of IVT for these patients. We compared the safety and outcomes of IVT in AIS patients with DOAC treatment and patients with no OAC before
Marius Matusevicius, Malin Säflund, Maurizio Balestrino, Manuel Cappellari, Delfina Ferrandi, Abdoreza Ghoreishi, André Peeters, Viiu‐Marika Rand, Manuela De Michele, Aleksandras Vilionskis, Andrea Zini, Niaz Ahmed   +11 more
wiley   +1 more source

A randomized, double-blind, placebo-controlled trial of nimodipine in acute ischemic hemispheric stroke. [PDF]

, 1994
Markku Kaste, R Fogelholm, T. Erilä, Heikki Palomäki, Kari Murros, A Rissanen, Seppo Sarna   +6 more
openalex   +1 more source

A Newly Defined, Common Ophthalmologic Condition Requires Special Neurological Attention

Annals of Neurology, EarlyView.
A host of acquired abnormalities in visual function are known to occur in persons who suffer stroke, traumatic brain injury, and neurodegenerative disorders. Cerebral visual impairment occurs in children with early neurological injury or disorders, especially neonatal hypoxic‐ischemic injury.
Kristina K. Hardy, Daofen Chen, Walter J. Koroshetz   +2 more
wiley   +1 more source

Adherence with cardiovascular medications and the outcomes in patients with coronary arterial disease: “Real‐world” evidence

Clinical Cardiology, Volume 45, Issue 12, Page 1220-1228, December 2022., 2022
Abstract Background Cardiovascular medications are vital for the secondary prevention of coronary arterial disease (CAD). However, the effect of cardiovascular medication may depend on the optimal adherence of the patients. This meta‐analysis aims to determine the magnitude of adherence to vascular medications that influences the absolute and relative ...
Chen Chen, Xiaoqing Li, Yuhao Su, Zhigang You, Rong Wan, Kui Hong   +5 more
wiley   +1 more source

A data-informed mathematical model of microglial cell dynamics during ischemic stroke in the middle cerebral artery [PDF]

arXiv
Neuroinflammation immediately follows the onset of ischemic stroke in the middle cerebral artery. During this process, microglial cells are activated in and recruited to the penumbra. Microglial cells can be activated into two different phenotypes: M1, which can worsen brain injury; or M2, which can aid in long-term recovery.
arxiv  

High Waist to Hip Ratio as a Risk Factor for Ischemic Stroke Patients Admitted in a Tertiary Care Hospital

, 1970
Md Habib Khan, Sanjoy Kumar Chakraborty, Rajat Sanker Roy Biswas   +2 more
openalex   +2 more sources

Circadian variation in the frequency of ischemic stroke. [PDF]

, 1990
C. Argentino, Danilo Toni, Maurizia Rasura, Francesco Violi, Maria Luisa Sacchetti, A. Allegretta, F Balsano, C. Fieschi   +7 more
openalex   +1 more source

Association Between Vascular NOTCH3 Aggregation and Disease Severity in a CADASIL Cohort – Implications for NOTCH3 Variant‐Specific Disease Prediction

Annals of Neurology, EarlyView.
Objective Vascular NOTCH3 protein ectodomain aggregation is a pathological hallmark of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), a monogenic small vessel disease typically caused by cysteine‐altering variants in NOTCH3.
Minne N. Cerfontaine, Gido Gravesteijn, Remco J. Hack, Kyra L. Dijkstra, Mar Rodríguez‐Girondo, Benno Gesierich, Marie‐Noëlle W. Witjes‐Ané, Remco van Doorn, Marco Duering, Julie W. Rutten, Saskia A. J. Lesnik Oberstein   +10 more
wiley   +1 more source