Results 181 to 190 of about 656,131 (350)

Type 2 diabetes mellitus in patients with ischemic stroke – A nationwide study [PDF]

Sidsel Hastrup, Jakob Nebeling Hedegaard, Grethe Andersen, Jørgen Rungby, Søren Paaske Johnsen   +4 more
openalex   +1 more source

Neuroprotective Nanoplatform Integrating Antioxidant MXene Nanozymes and Ferroptosis Inhibitors for Targeted Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Cerebral ischemia‐reperfusion injury (CIRI) is a key pathological process limiting the efficacy of stroke therapy. This study has developed an innovative, multifunctional, brain‐targeted nanoplatform (RFP) containing MXene nanoenzymes and ferroptosis inhibitors.
Lu Wang, Chao Hou, Shuo Li, Lizhi Yang, Yiqun Lin, Sen Wang, Xiaohua Jia, Hui Hui, Wen He, Wei Zhang   +9 more
wiley   +1 more source

The Cerebellar Connectome Disruptions in Ischemic Stroke. [PDF]

CNS Neurosci Ther
Wang X, Li T, Wang J, Fu Y, Ma Z, Wu X, Wang Y, Zang Y, Song Y, Lv Y.   +9 more
europepmc   +1 more source

Disrupting CSPG‐Driven Microglia–Astrocyte Crosstalk Enables Scar‐Free Repair in Spinal Cord Injury

Advanced Science, EarlyView.
This study identifies CSPGs as key drivers of glial scar maturation after spinal cord injury by reprogramming microglial metabolism and inducing astrocyte fibrosis. To address this, a reactive oxygen species‐responsive, reactive astrocyte‐targeted ChABC gene delivery system is designed to locally degrade CSPGs, precisely disrupt maladaptive glial ...
Yufei Zheng, Zhaowei Zhang, Zezhou Fu, Qingqing Wang, Siwen Zhang, Tingyu Zhang, Meifei Zhu, Shunwu Fan, Youqing Shen, Jiajia Xiang, Xin Liu   +10 more
wiley   +1 more source

Monocyte-derived macrophages and their roles in ischemic stroke. [PDF]

J Cereb Blood Flow Metab
Dufort C, Tian Q, Lu L, Tong Y, Du Z, Rios Sigler A, Mathys H, Leak RK, Wang M, Hu X.   +9 more
europepmc   +1 more source

Correlation Between Neuron-Specific Enolase and Serum Glucose Level in Patients with Acute Ischemic Stroke [PDF]

, 2019
Hong Duc Thi Nguyen
openalex   +1 more source

CRISPLD2 Attenuates Intervertebral Disc Degeneration by Suppressing Oxidative Stress‐Induced Ferroptosis through the miR‐548I‐IL17A Axis

Advanced Science, EarlyView.
This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi, Fudong Li, Tianyi Zhao, Kaiqiang Sun, Danying Zhang, Chen Yan, Ximing Xu, Jingchuang Sun, Xulin Hu, Xin Yong, Jiangang Shi, Yuan Wang   +11 more
wiley   +1 more source

Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review). [PDF]

Mol Med Rep
Wang X, Zhang X, Lin J, Lin P.
europepmc   +1 more source

Diagnostic Work-Up and Etiology in Ischemic Stroke in Young Adults: Before and Now

, 2012
José F. Varona
openalex   +1 more source

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

Advanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source