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Molecular epidemiology of Infectious Spleen and Kidney Necrosis Virus (ISKNV) in Ghanaian cultured tilapia

2022
1 ABSTRACT Infectious Spleen and Kidney Necrosis Virus (ISKNV) is increasingly gaining more attention globally, due to its highly significant economic impact on the aquaculture industry. In late 2018, unusually high levels of mortality (60-90%) was reported in some intensive tilapia cage culture systems in Ghana ...
Angela Naa Amerley Ayiku   +10 more
openaire   +1 more source

Transcriptomic and Proteomic Analyses of the Immune Mechanism in Pathogenetic and Resistant Mandarin Fish (Siniperca chuatsi) Infected With ISKNV

Aquaculture, 2021
Abstract Mandarin fish (Siniperca chuatsi) is one of the most economically important aquaculture species in China. Mandarin fish aquaculture has experienced major losses in the past few decades because of outbreaks of infectious spleen and kidney necrosis virus (ISKNV). Little is known about the immune mechanism of pathogenetic and resistant mandarin
He-Zhong Huang, Huang-Cui Fu
exaly   +2 more sources

Characterization of a membrane protein (VP001L) from infectious spleen and kidney necrosis virus (ISKNV)

Virus Genes, 2007
Infectious spleen and kidney necrosis virus (ISKNV) is the type species of megalocytivirus, Iridoviridae. A novel membrane protein corresponding to the first open reading frame (ORF001L) of ISKNV genome was identified. This 378-residue protein, termed the VP001L protein, has a high content of hydrophobic sequences and contains 10-11 putative ...
Xiaopeng, Xu   +5 more
openaire   +2 more sources

Antiviral functions of IFNd against ISKNV and interaction analysis of IFNd and its receptors in spotted seabass (Lateolabrax maculatus)

Fish & Shellfish Immunology, 2023
Type I interferons (IFNs) play a significant role in antiviral innate immunity. But, the antiviral function of IFNd is controversial in teleosts. Here, we identified three IFNd receptors belonging to cytokine receptor family B (LmCRFB1, LmCRFB2, and LmCRFB5) in spotted seabass (Lateolabrax maculatus).
Lulu, Yan   +5 more
openaire   +2 more sources

RING finger proteins of infectious spleen and kidney necrosis virus (ISKNV) function as ubiquitin ligase enzymes

Virus Research, 2007
Infectious spleen and kidney necrosis virus (ISKNV) is the etiological agent that causes a pandemic and severe disease in fish characteristic of enlarged and damaged spleen and kidney. To identify viral proteins involved in infection and pathogenesis, we characterized five open reading frames (ORFs) of the ISKNV genome, ORF12, ORF65, ORF66, ORF99 and ...
Junfeng, Xie   +8 more
openaire   +2 more sources

Experimental Transmission, Pathogenicity and Physical–Chemical Properties of Infectious Spleen and Kidney Necrosis Virus (ISKNV)

Aquaculture, 2002
The pathogenicity of infectious spleen and kidney necrosis virus (ISKNV) was examined by infection trials in the first known host species, the mandarinfish, Siniperca chuatsi, and in 20 other teleosts cultured in China. Mandarinfish and large-mouth bass, Micropterus salmoides, were highly susceptible to infection after intraperitoneal infection of ...
J.G He, K Zeng, S.P Weng, S.-M Chan
exaly   +2 more sources

Molecular cloning of IKKβ from the mandarin fish Siniperca chuatsi and its up-regulation in cells by ISKNV infection

Veterinary Immunology and Immunopathology, 2011
The IκB kinase β (IKKβ) plays crucial roles in regulating activation of nuclear factor-kappa B (NF-κB) in response to proinflammatory factors and microbial and viral infections. Here, we report the cloning of an IKKβ cDNA (named SicIKKβ) from the mandarin fish Siniperca chuatsi.
Wei-Jian, Chen   +8 more
openaire   +2 more sources

Characteristics of the interferon regulatory factor pairs zfIRF5/7 and their stimulation expression by ISKNV Infection in zebrafish (Danio rerio)

Developmental & Comparative Immunology, 2010
The interferon regulatory factor (IRF) family plays critical roles in a host's virus infection responses. In this study, two IRF family members, zfIRF5 and zfIRF7, are identified in zebrafish. The zfIRF5 protein encodes 297 amino acids without the carboxyl IRF3 domain.
Zhiming, Xiang   +10 more
openaire   +2 more sources

In field use of water samples for genomic surveillance of ISKNV infecting tilapia fish in Lake Volta, Ghana

2023
Abstract Viral outbreaks are a constant threat to aquaculture, limiting production for better global food security. A lack of diagnostic testing and monitoring in resource-limited areas hinders the capacity to respond rapidly to disease outbreaks and to prevent viral pathogens becoming endemic in fisheries productive ...
Shayma Alathari   +10 more
openaire   +1 more source

Molecular epidemiology and phylogenetic analysis of a marine fish infectious spleen and kidney necrosis virus-like (ISKNV-like) virus

Archives of Virology, 2006
Infectious spleen and kidney necrosis virus-like (ISKNV-like) virus causes a serious systemic disease with high morbidity and mortality of freshwater and marine fishes. Based on the ISKNV putative major capsid protein (MCP), the vascular endothelial growth factor (VEGF), the mRNA capping enzyme (Capping), and the tumor necrosis factor receptor ...
Y Q, Wang   +5 more
openaire   +2 more sources

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