Results 231 to 240 of about 20,996 (256)
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Amyloidogenesis of Islet Amyloid Polypeptide (IAPP)
2005Our studies suggest that insoluble amyloid formation by IAPP follows kinetics that are consistent with a nucleation-dependent polymerization mechanism. Thus, IAPP amyloid formation can be accelerated by seeding with preformed IAPP amyloid fibrils. At the molecular level, IAPP amyloid formation was found to proceed via a conformational transition into ...
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The amyloid hypothesis in Alzheimer disease: new insights from new therapeutics
Nature Reviews Drug Discovery, 2022Eric Karran, Bart De Strooper
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Mechanisms controlling pancreatic islet cell function in insulin secretion
Nature Reviews Molecular Cell Biology, 2021Jonathan Campbell, Christopher B Newgard
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Islet-amyloid polypeptide in human plasma
The Lancet, 1990Van Jaarsveld, B. C. +5 more
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Amyloid β-based therapy for Alzheimer’s disease: challenges, successes and future
Signal Transduction and Targeted Therapy, 2023Weihong Song
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Amyloid-type Protein Aggregation and Prion-like Properties of Amyloids
Chemical Reviews, 2021Dieter Willbold +2 more
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Mechanisms and pathology of protein misfolding and aggregation
Nature Reviews Molecular Cell Biology, 2023Nikolaos N Louros, Frederic Rousseau
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The amyloid state and its association with protein misfolding diseases
Nature Reviews Molecular Cell Biology, 2014Tuomas P J Knowles +2 more
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