Results 151 to 160 of about 424,952 (202)
Insights Into the Interplay Between the Senescent Cells and Immune Cells
Aging Cell, Volume 25, Issue 9, September 2026.Kidney aging is associated with increased proximal tubular senescence and leukocyte infiltration. Senolytic treatment reduces senescent cell burden and overall immune cell infiltration. However, macrophages remain enriched around residual senescent cells.
Martin Jaros +7 more
wiley +1 more source
Acta Physiologica, Volume 242, Issue 9, September 2026.ABSTRACT MicroRNAs (miRNAs) have emerged as central regulators of pancreatic islet biology, influencing β‐cell development, proliferation, and function. In type 2 diabetes (T2D), both adaptive and maladaptive miRNA responses shape β‐cell compensation and progressive secretory dysfunction.
Lena Eliasson +3 more
wiley +1 more source
Implementing Best Practice Guidelines in Autologous Islet Transplantation through an International Survey [PDF]
openBackground - Islet Autotransplantation (IAT) following pancreatectomy due to chronic pancreatitis (CP) serves as a mitigation strategy against postoperative diabetes.
ZANOLETTI, MARTA
core
Clinical Transplantation, Volume 40, Issue 9, September 2026.ABSTRACT Background Donor/recipient HLA molecular mismatches are predictive of kidney transplant outcomes. Their role in pancreas transplantation has not been well studied. Methods We conducted a retrospective cohort study in 281 pancreas (± kidney) transplant recipients during 2000–2018, followed for average 53.8 months.
Zakieh Zare +8 more
wiley +1 more source
Tipping Points in Bacterial Richness Amplify Extracellular Enzyme Activities in Northern Peatlands
Global Change Biology, Volume 32, Issue 9, September 2026.Using a trans‐Holarctic survey in Sphagnum‐dominated peatlands, we identify a critical bacterial biodiversity threshold. Below this threshold, ecosystem function shifts, increasing enzyme activities by 60%, potentially accelerating carbon turnover. This weakens the peatland carbon sink, emphasizing the need to safeguard diversity.
Vincent E. J. Jassey +75 more
wiley +1 more source
Journal of Cellular and Molecular Medicine, Volume 30, Issue 17, September 2026.ABSTRACT Insulin resistance (IR) is the key driver of type 2 diabetes mellitus, metabolic dysfunction‐associated steatotic liver disease, and cardiometabolic disorders. Mesenchymal stem cell‐derived exosomes (MSC‐Exos) as a potent cell‐free alternative can deliver miRNAs, proteins, and mitochondrial regulators to reactivate the IRS1/PI3K/Akt/GLUT4 axis.
Qinghua Jia +6 more
wiley +1 more source
Characterising Hepatitis D Virus in the UK From 2011 to 2021
Journal of Viral Hepatitis, Volume 33, Issue 9, September 2026.ABSTRACT Little is known about hepatitis B virus (HBV) and Hepatitis D virus (HDV) coinfection in the UK. HDV screening is recommended among all individuals with HBV, with coinfection associated with increased disease progression. Using data on HDV testing, shared by 11 laboratories in the UK who reported undertaking HDV testing, and national testing ...
R. Simmons +67 more
wiley +1 more source
Quantification of Islet Cell Cluster Size Heterogeneity in Early Postnatal Porcine Pancreas
Xenotransplantation, Volume 33, Issue 5, September/October 2026.ABSTRACT Donor scarcity limits islet transplantation for type 1 diabetes. Early postnatal piglets are a potential xenogeneic source of endocrine tissue, yet their immature islet cell clusters (ICCs) remain insufficiently characterised with respect to size and maturation.
Daviana Munoz Cruz +4 more
wiley +1 more source
Flow Cytometric Immune Profiling Enables Early Detection of Rejection in Islet Xenotransplantation
Xenotransplantation, Volume 33, Issue 5, September/October 2026.ABSTRACT Background Islet xenotransplantation is a strategy for treatment of Type 1 Diabetes, but immune‐mediated rejection limits graft survival. This study investigated a strategy with flow cytometry–based immune monitoring to evaluate immunosuppressive therapy and provide indicators of graft rejection.
Huu Thanh Le +10 more
wiley +1 more source
Islet Cell Transplantation [PDF]
Journal of the Royal Society of Medicine, 2002 Terry, Samuel, Paul, Cockwell
openaire +2 more sources