Results 141 to 150 of about 424,952 (202)

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Coaxial Electrospinning of Multicomponent Fiber Membranes for Sustained Oxygen Supply in Hypoxic Environment

Journal of Biomedical Materials Research Part A, Volume 114, Issue 9, September 2026.
Core‐sheath fiber membrane produced by coaxial electrospinning contains calcium peroxide providing oxygen for pancreatic islets in a hypoxic environment, resulting in enhanced cell viability. Catalase enzyme was embedded in the fiber sheath, significantly reducing production of cytotoxic hydrogen peroxide while increasing release of oxygen.
Brooke Campbell, Houra Mobaleghaleslam, Robert Horvath, Daewoo Han, Hiroyuki Kato, Hirotake Komatsu, Andrew J. Steckl   +6 more
wiley   +1 more source

Bioengineered sites for islet cell transplantation.

, 2013
Although islet transplantation has demonstrated its potential use in treating type 1 diabetes, this remains limited by the need for daily immunosuppression.
Dufrane, Denis, Veriter, Sophie, Gianello, Pierre   +2 more
core   +1 more source

Organ‐Specific Human Microbiomes and Dysbiosis: Mechanistic Links to Disease and Emerging Therapeutic Strategies

Journal of Clinical Laboratory Analysis, Volume 40, Issue 18, September 2026.
Schematic overview of the human microbiome and major microbiota‐derived metabolites across body sites, highlighting the gut–brain, gut–heart, and gut–kidney axes in host physiology and disease. ABSTRACT Background The human microbiome is a dynamic and diverse community of microorganisms that affects susceptibility to illness and promotes wellness ...
Awadh Alanazi
wiley   +1 more source

Natural Product‐Derived Vesicles in Nanotherapeutics

Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
Natural product‐derived vesicles (NPVs) are an emerging nature‐based nanotherapeutic that can deliver bioactive metabolites into the target site and induce beneficial mechanisms. A practical, chronological bench‐to‐bedside approach throughout the entire NPV development process is expected to resolve challenges encountered in NPV studies.
Kartiko Arif Purnomo, Tsong‐Long Hwang
wiley   +1 more source

Treadmill Training Improves Functional Recovery After Injection of Adipose‐Derived Stromal Vascular Fraction in Rats With a Spinal Cord Injury

Journal of Neuroscience Research, Volume 104, Issue 9, September 2026.
In this study, we investigated the effect of a strategy combining stromal vascular fraction (SVF) autograft with treadmill training after a spinal cord injury in rats. SVF injection was performed within the 4 h post‐injury. Analysis was performed using behavior tests (BBB and ladder climbing tests), gait analysis on a walking corridor, and ...
Céline Ertlen, Maxime Bonnet, Mostafa Seblani, Thelma Coyle, Jean‐Michel Brezun, Nicolas Serratrice, Patrick Decherchi, Tanguy Marqueste   +7 more
wiley   +1 more source

Amino Acid Metabolism in Health and Disease

MedComm, Volume 7, Issue 9, September 2026.
This graphical abstract delineates the multifaceted role of amino acid metabolism in health and disease. It illustrates how amino acids sustain physiological homeostasis across the liver, kidney, brain, heart, intestine, muscle, skeleton, and immune system.
Zhiwei Su, Jinyu Liu, Xiaoliang Deng, Yanqun Luo, Haiping Xue, Lei Wang, Lianjun Xing, Tao Wu   +7 more
wiley   +1 more source

Role of Tertiary Lymphoid Structures in Autoimmune Diseases and Cancer

MedComm, Volume 7, Issue 9, September 2026.
Schematic overview of tertiary lymphoid structures (TLSs): The development process, detection, and the immune function that depends on the environment in different disease contexts of TLS. TLSs originate from loose lymphoid aggregates that acquire ordered follicular architecture to become primary follicular‐like TLS, before maturing into ...
Ze Yan, Bin Wen, Ying Hu, Xiaocui Wang, Xuemei Duan, Haonan Li, Shumin Dong, Yufeng Fan, Caihong Wang, Shutong Yang, Huifeng Shang, Yukai Jing   +11 more
wiley   +1 more source

Single-donor islet transplantation in type 1 diabetes: patient selection and special considerations

, 2017
Jacob A Tatum,* Max O Meneveau,* Kenneth L Brayman Department of Surgery, Division of Transplantation, The University of Virginia Health System, Charlottesville, VA, USA *These authors contributed equally to this work. Abstract: Type 1 diabetes
Meneveau MO, Brayman KL, Tatum JA
core  

When Fat Goes Astray: Your Liver and Pancreas Get Into Trouble

Portal Hypertension &Cirrhosis, Volume 5, Issue 3, Page 269-282, September 2026.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) and intrapancreatic fat deposition (IPFD) are both common manifestations of ectopic fat accumulation. Although they share multiple risk factors, they also show notable differences in pathological features, standardization of diagnosis, and research maturity.
Yuying Chen, Li Ding, Shan Zhao, Weihong Wang, Jing Zhong, Qiang Yan   +5 more
wiley   +1 more source