Results 121 to 130 of about 424,952 (202)
, 2014 Background Transplantation of islets of Langerhans (islets) was used to treat insulin-dependent diabetes mellitus. However, islet grafts must be maintained by administration of immunosuppressive drugs, which can lead to complications in the long term. An
Xibao Liu +9 more
core +1 more source
Cell Transplantation, 1999 For clinical islet cell transplantation, short-term storage of islet cells is likely to be necessary, and it is imperative that the islet cells be kept as viable as possible during the period.
Shigeo Kanazawa +7 more
doaj +1 more source
, 2014 Pancreatic islet transplantation has the potential to become the most physiologically advantageous and minimally invasive procedure for the treatment of type 1 diabetes mellitus. Since the first clinical islet transplantation was performed at the University of Minnesota in 1974 [1], the results have been far from ideal for more than two decades in ...
Kenmochi, Takashi +3 more
openaire +1 more source
The Baboon as a Model to Study Human Health and Complex Disease
American Journal of Primatology, Volume 88, Issue 9, September 2026.Baboons remain underappreciated as models of human biology and disease offering a distinct combination of biological and practical properties. In this review, we evaluate the baboon as a model for human complex diseases and make the case for broader use of baboons in translational research.
Brittany Hazzard, Yoav Gilad
wiley +1 more source
Bioengineering approaches to islet transplantation for management of diabetes
, 2017 Human islet transplantation, as currently carried out by portal vein infusion in the liver, can provide good glycaemic control in diabetic patients and can significantly reduce the need to inject exogenous insulin.
Tuch, Bernard E. +5 more
core +1 more source
Islet transplantation in Italy.
CellR4-- repair, replacement, regeneration, & reprogramming, 2019 Two centers have now an active islet transplant program in Italy, both placed in Milan: the San Raffaele Scientific Institute and the Niguarda Hospital. Up to 2018 in Italy about 200 patients affected by type 1 diabetes mellitus received an islet allotransplantation and about 100 patients received an islet auto-transplantation after a partial or total ...
openaire +3 more sources
Current Protocols, Volume 6, Issue 9, September 2026.Abstract The most common treatment for people with people with type 1 diabetes (T1D) requires injections of exogenous insulin to regulate blood glucose homeostasis. A longer‐term therapeutic solution for T1D has emerged whereby patients may regain insulin independence through transplantation of donated human pancreatic islets, which contain insulin ...
Manuj Bandral +2 more
wiley +1 more source
Islet transplantation : The quest for an ideal source
Annals of Saudi Medicine, 2008 The progress of islet transplantation as a new therapy for patients with diabetes mellitus depends directly upon the development of efficient and practical immunoisolation methods for the supply of sufficient quantities of islet cells.
Younes Nidal +2 more
doaj
Diabetes/Metabolism Research and Reviews, Volume 42, Issue 6, September 2026.ABSTRACT Type 1 Diabetes (T1D) is an autoimmune disorder marked by the immune‐mediated destruction of pancreatic β‐cells, resulting in insulin deficiency and dysregulated glucose control. Current therapies—such as insulin replacement and artificial pancreas systems—manage symptoms but fail to restore endogenous β‐cell function or halt disease ...
Fatemeh Sabet Sarvestani +4 more
wiley +1 more source