Results 111 to 120 of about 424,952 (202)

Low molecular weight dextran sulfate: a strong candidate drug to block IBMIR in clinical islet transplantation.

, 2006
The instant blood-mediated inflammatory reaction (IBMIR) is triggered in clinical islet transplantation when human pancreatic islets come in contact with blood and may explain the initial tissue loss associated with this procedure.
Goto, M.,, Johansson, H., Korsgren, Olle,, Siegbahn, A, Korsgren, O, Nilsson, Bo,, Gianello, P., Goto, M, Dufrane, Denis, Siegbahn, Agneta,, Johansson, H.,, Elgue, G., Dufrane, D., Nilsson, B, Elgue, Graciela,, Gianello, Pierre   +15 more
core   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

Continuous Intraperitoneal Insulin Infusion for People With Type 1 Diabetes: A Literature Review and International Position Statement

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 8801-8811, October 2026.
ABSTRACT Achieving glucose targets without hypoglycaemia is the treatment goal in type 1 diabetes. Structured education, intensified insulin injection regimens, continuous glucose monitoring, automated insulin delivery, and ongoing support from a multidisciplinary team all support people with type 1 diabetes to achieve this goal. Despite these advances,
Nick Oliver, Bernhard Gehr, Rayhan Lal, Peter R. van Dijk, Eric Renard   +4 more
wiley   +1 more source

Soluble Immune Checkpoints and Anti‐HLA Antibodies in Kidney Transplant Recipients: Associations With Kidney Function

Immunology, Volume 179, Issue 2, Page 269-286, October 2026.
Soluble immune checkpoints, anti‐HLA panel‐reactive antibodies, and kidney function parameters were evaluated to investigate their associations with early graft function. Pre‐transplant patients showed higher levels of sCD25, sPD‐L1, sTIM‐3, Gal‐9, sCD27, and sPD‐L2 than healthy controls, while post‐transplant temporal changes were observed in sCD25 ...
Cemil Pehlivanoğlu, Fırat Demircan, Başak Aru, Süheyla Apaydın, Abdullah Demir, Rabia Tığlı, Gürkan Tellioğlu, Ali Osman Gürol, Gülderen Yanıkkaya Demirel   +8 more
wiley   +1 more source

Advances in the treatment of systemic lupus erythematosus: Biologicals, small‐molecular agents, and cell‐depleting therapies coming to the clinic

Journal of Internal Medicine, Volume 300, Issue 4, Page 461-479, October 2026.
Abstract Systemic lupus erythematosus (SLE; lupus) remains a particular challenge for the practicing clinician on account of its chronic undulating and unpredictable course, its diverse manifestations, and—until recently—limited treatment options all associated with considerable downsides.
Ronald van Vollenhoven
wiley   +1 more source

Extensive Loss of Islet Mass Beyond the First Day After Intraportal Human Islet Transplantation in a Mouse Model

, 2016
Clinical islet transplantation is characterized by a progressive deterioration of islet graft function, which renders many patients once again dependent on exogenous insulin administration within a couple of years.
Carlsson, Per-Ola,, Liljebäck, Hanna,, Olerud, Johan,, Grapensparr, Liza,   +3 more
core   +1 more source

Treating diabetes with islet transplantation : Lessons learnt from the Nordic network for clinical islet transplantation

, 2019
In this chapter we present the Nordic experiences withclinical islet transplantation after starting networks. TheNordic Network for Clinical Islet Transplantation (NNCIT)was established in 2000.
von Zur-Mühlen, Bengt,, Korsgren, Olle,, Lundgren, Torbjörn, Hellman, Jarl,, Scholz, Hanne   +4 more
core   +2 more sources

Synthesis and Characterization of Biocompatible Manganese‐Doped Titania Nanoparticles and Its Application to Single‐Cell Nanoencapsulation

Advanced Materials Interfaces, Volume 13, Issue 18, 22 September 2026.
Biocompatible Mn‐doped TiO2 nanozymes integrate TiO2 stability with Mn redox activity, enabling dopamine‐mediated cell‐surface polymerization and single‐cell nanoencapsulation while maintaining high colloidal stability, low ROS generation, and excellent cellular compatibility.
Filip Kozłowski, Nayoung Kim, Hyunwoo Choi, Geoffrey Daniel, Gulaim A. Seisenbaeva, Insung S. Choi, Vadim G. Kessler   +6 more
wiley   +1 more source

Bacteremia due to Transplantation of Contaminated Cryopreserved Pancreatic Islets

Cell Transplantation, 1994
Objective To report two cases of pancreatic islet transplantation-related septicemia, and the results of an investigative protocol to identify potential sources of contamination. Design Case series.
Geoffrey D. Taylor, Terri Kirkland, Jonathan Lakey, Ray Rajotte, Garth L. Warnock   +4 more
doaj   +1 more source

Autoantigen mRNA‐LNP Vaccination Drives Therapeutic Efficacy in Preclinical Models for Autoimmunity

Advanced Science, Volume 13, Issue 53, 24 September 2026.
Systemic and intramuscular delivery of autoantigen mRNA via lipid nanoparticles reprograms antigen‐presenting cells toward a mature, homeostatic state, driving antigen‐specific T cell exhaustion and providing therapeutic efficacy across autoimmune disease models.
Paulien Baeten, Karen Beets, Tessa Schalley, Janne Verreycken, Gayel Duran, Daphne Lintsen, Lisa Schuetz, Xue Zhong, Rinke Nieuwschepen, Melissa Schepers, Brecht Moonen, Jeroen Bogie, Jana Van Broeckhoven, Carlo Heirman, Jurgen Van den Heuvel, Bart Vanderborght, Ismael Varela, Roxanne Nouille, Lotte Jacobs, Jessica Filtjens, Sabah Kasmi, Elise Seynaeve, Veronica Mavrovouna, Jana De Vrieze, Michael A. Brehm, Sandra Maréchal, Sophie Janssens, Florence Lambolez, Niels Hellings, Stefaan De Koker, Bieke Broux   +30 more
wiley   +1 more source