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Transplantation of Pancreatic Islets
Upsala Journal of Medical Sciences, 1981 B, Petersson +7 more
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Roles of Toll-Like Receptors in Allogeneic Islet Transplantation
, 2012 Background: Toll-like receptors (TLRs) are involved in the rejection of solid organ allografts. However, the roles of TLRs in islets are still controversial.
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The Clinical Impact of Islet Transplantation
American Journal of Transplantation, 2008 Islet cell transplantation has recently emerged as one of the most promising therapeutic approaches to improving glycometabolic control in diabetic patients and, in many cases, achieving insulin independence.
Camillo Ricordi +2 more
exaly +3 more sources
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Journal of Hepato-Biliary-Pancreatic Surgery, 2000
Recently, significant advances have been made in the number and purity of islets that can be retrieved from the human pancreas, thus enabling several centers to initiate or resume clinical trials of islet transplantation in type I diabetic patients. Although the success rate of islet transplantation is lower than that of pancreas transplantation in ...
K, Inoue, M, Miyamoto
openaire +2 more sources
Recently, significant advances have been made in the number and purity of islets that can be retrieved from the human pancreas, thus enabling several centers to initiate or resume clinical trials of islet transplantation in type I diabetic patients. Although the success rate of islet transplantation is lower than that of pancreas transplantation in ...
K, Inoue, M, Miyamoto
openaire +2 more sources
Clinical islet transplantation
Current Diabetes Reports, 2003Type 1 diabetes affects over 1 million persons in the United States, with over 30,000 new cases diagnosed annually. Transplantation of new insulin-producing b cells, in the form of the whole pancreas or isolated islets, has been shown to ameliorate the disease by eliminating the need for exogenous insulin and normalizing glycosylated hemoglobin levels.
Dixon B, Kaufman, William L, Lowe
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Allogeneic islet transplantation
Expert Opinion on Biological Therapy, 2007Significant progress has been made in the field of beta-cell replacement therapies by islet transplantation in patients with unstable Type 1 diabetes mellitus (T1DM). Recent clinical trials have shown that islet transplantation can reproducibly lead to insulin independence when adequate islet numbers are implanted.
Simona, Marzorati +2 more
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Seminars in Pediatric Surgery, 2014
Islet transplantation has become a promising treatment for selected patients with type 1 diabetes. Here we provide an overview of the procedure including its history, the process of donor selection, and the techniques and procedures involved in a successful transplant.
Michael, McCall, A M James, Shapiro
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Islet transplantation has become a promising treatment for selected patients with type 1 diabetes. Here we provide an overview of the procedure including its history, the process of donor selection, and the techniques and procedures involved in a successful transplant.
Michael, McCall, A M James, Shapiro
openaire +2 more sources
Pancreatic and islet transplantation
Current Gastroenterology Reports, 2000Diabetes mellitus is the most devastating chronic disease of all time. This review discusses the current therapies for type 1 diabetes that are predicated on the restoration of insulin secretion by transplantation. Recent developments in vascularized pancreas transplantation have led to a dramatic increase in the number of these procedures performed ...
openaire +2 more sources