Results 141 to 150 of about 28,614 (251)

Nano‐Gs Protein Peptidomimetics: Rational Design of Gα C‐Terminus‐Derived Peptides Mimicking Key Components of Gs‐β2AR Interactions

Angewandte Chemie International Edition, EarlyView.
G protein‐coupled receptors (GPCRs) are major therapeutic targets. Modulating GPCR activity through intracellular sites is evolving. A structure‐ and computation‐assisted approach generated small G protein‐derived peptidomimetics targeting the intracellular binding crevice of the β2 adrenergic receptor mimicking features of the full G protein.
Phuong Thu Tran, Mia Danielsen, Johanna K. S. Tiemann, Passainte Ibrahim, Søren G. F. Rasmussen, Xavier Kubiak, Hossein Batebi, Charlène Gadais, Steven Ballet, Peter W. Hildebrand, Daniel Sejer Pedersen, Jesper Mosolff Mathiesen   +11 more
wiley   +1 more source

Design of Experiments‐Based Optimization of Recovered Carbon Black–Reinforced Isobutylene–Isoprene Rubber in Comparison With Conventional Carbon Black Systems

Journal of Applied Polymer Science, EarlyView.
Optimized potential of rCB via DOE: recovered carbon black from end‐of‐life tires was assessed as a full substitute for conventional carbon black in IIR composites. DOE and response surface methodology optimized rCB loading, plasticizer, and sulfur contents. Hardness showed linear trends, while rupture energy was nonlinear.
Vinícius Guedes Gobbi, Ester Costa de Almeida, Roberta Helena Mendonça, Marysilvia Ferreira da Costa   +3 more
wiley   +1 more source

Growth Hormone Promotes Lipolysis and Impairs Insulin Sensitivity by Activating the ERK/HSL Signaling Pathway in Bovine Adipocytes

Animal Research and One Health, EarlyView.
This study was to evaluate the role of GH in lipolysis and insulin sensitivity in bovine adipocytes and clarify the underlying mechanism. Our findings demonstrate that GH activates ERK/HSL signaling pathway, promotes lipolysis, and impairs insulin sensitivity in bovine adipocytes.
Xinxing Gao, Hao Yu, Erminio Trevisi, Cai Lin, Zhiyuan Fang, Xinwei Li, Yuxiang Song, Wenwen Gao, Lin Lei, Xiliang Du, Guowen Liu   +10 more
wiley   +1 more source

Dietary Mannan‐Rich Fractions Attenuate Weaning Stress in Piglets via Modulating Gut Microbiota and TLR5/NF‐κB Signaling

Animal Research and One Health, EarlyView.
This study aimed to investigate the potential of a mannan‐rich fraction (MRF) as a dietary intervention to alleviate weaning stress in piglets. Our results revealed that MRF could alleviate weaning stress by modulating the gut microbiota and the TLR5/NF‐κB signaling pathway, offering a novel and sustainable alternative to antibiotic use in swine ...
Yutong Lu, Yiwei Sun, Kun Cai, Pingli He, Gang Lin, Zengkai Qi, Hu Liu, Junshu Yan, Ning Ma   +8 more
wiley   +1 more source

Defect engineering for highly efficient and stable perovskite top cells for Si tandems

Bulletin of the Korean Chemical Society, EarlyView.
Defect passivation in wide‐bandgap perovskites is essential for enabling high‐efficiency and stable perovskite/Si tandem solar cells. Bulk, surface, and buried‐interface passivation strategies focus on suppressing nonradiative recombination, ion migration, and halide segregation, thereby clarifying critical design principles for next‐generation tandem ...
Ju Yeong Hong, Young Seon Yoon, Jin Young Kim   +2 more
wiley   +1 more source

Elucidating the Interplay Between Structure and Electrochemical Behavior in Lignin‐Based Polymer Electrolytes for Potassium Batteries

Battery Energy, Volume 4, Issue 2, March 2025.
Three biobased membranes are synthesized by crosslinking oxidized Kraft lignin with poly(ethylene glycol) diglycidyl ether of increasing molecular weights. After incorporation of solvated potassium salts, potassium batteries including these biobased gel polymer electrolytes are able to deliver a maximum specific capacity at 0.05 A g−1 as high as 130 ...
Giuseppe Pascuzzi, Sabrina Trano, Carlotta Francia, Stefano Turri, Federico Bella, Gianmarco Griffini   +5 more
wiley   +1 more source

Analytical and sensory assessment of the flavour stability impact of dry-hopping in single-hop beers [PDF]

, 2012
Aerts, Guido, Borremans, Yvan, De Clippeleer, Jessika, De Cooman, Luc, De Keukeleire, Denis, Jaskula-Goiris, Barbara, Naudts, Dirk, Van Holle, Ann, Van Nieuwenhove, Jan, Van Opstaele, Filip   +9 more
core  

Human bitterness detection thresholds of hop acids in beer and honey [PDF]

Alpha acids are found in the lupulin glands of hops cones. These acids have no bitterness of their own, but can be isomerized and subsequently hydrogenated to form bitter iso-α-acids and tetrahydroiso-α-acids respectively.
Kolpin, Kathryn M.
core   +1 more source

Scalable desolvation synthesis, storage stability, and comprehensive biophysical characterization of human hemoglobin nanoparticles as a potential hemoglobin‐based oxygen carrier

Biotechnology Progress, EarlyView.
This work describes the development of human hemoglobin nanoparticles using an anti‐solvent precipitation synthesis method as a potential next generation hemoglobin‐based oxygen carrier. The hemoglobin nanoparticles are uniform in size and shape, hemocompatible, stable at various storage conditions, and demonstrate a scalable synthesis technique ...
Alisyn Greenfield, Andre F. Palmer
wiley   +1 more source

Insights into the Photocatalytic Arene Bromination Enabled by Cs2AgBiBr6 Microparticles

Chemistry – A European Journal, EarlyView.
A sustainable photocatalytic bromination of electron‐rich arenes is enabled by low‐toxicity Cs2AgBiBr6 double‐perovskite microparticles using HBr as an atom‐economical bromine source. Surface‐derived bromine radicals drive highly selective mono‐bromination under mild conditions.
Daniele Conelli, Chiara Lo Porto, Mokurala Krishnaiah, Kimmo Lahtonen, G. Krishnamurthy Grandhi, Nicola Margiotta, Paola Vivo, Gian Paolo Suranna, Roberto Grisorio   +8 more
wiley   +1 more source