Matured Hop Bitter Acids in Beer Improve Lipopolysaccharide-Induced Depression-Like Behavior [PDF]
Frontiers in Neuroscience, 2019 Recent studies have demonstrated a close association between neural inflammation and development of mental illnesses, such as depression. Clinical trials have reported that treatment with non-steroidal anti-inflammatory drugs is associated with reduced ...
Takafumi Fukuda +3 more
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Effect of non‐alcoholic beer containing matured hop bitter acids on mood states in healthy adults: A single‐arm pilot study [PDF]
Australian Journal of Cancer Nursing, 2022 AbstractThis study aimed to investigate the effect of non‐alcoholic beer containing matured hop bitter acids on mood states among healthy adults older than 20 years. This study was an open‐label longitudinal intervention design in which each participant served as their control. For 3 weeks, we evaluated the effect of non‐alcoholic beer containing 35 mg
Takafumi Fukuda, Yasuhisa Ano
exaly +5 more sources
Improving Effects of Hop-Derived Bitter Acids in Beer on Cognitive Functions: A New Strategy for Vagus Nerve Stimulation [PDF]
Biomolecules, 2020 Dementia and cognitive decline are global public health problems. Moderate consumption of alcoholic beverages reduces the risk of dementia and cognitive decline.
Tatsuhiro Ayabe +2 more
doaj +4 more sources
Supplementation with Matured Hop Bitter Acids Improves Cognitive Performance and Mood State in Healthy Older Adults with Subjective Cognitive Decline [PDF]
Journal of Alzheimer's Disease, 2020 Background: Prevention of age-related cognitive decline and depression is becoming urgent because of rapid growing aging populations. Effects of vagal nerve activation on brain function by food ingredients are inadequately investigated; matured hop bitter acid (MHBA) administration reportedly improves cognitive function and depression via vagal nerve ...
Takafumi Fukuda, Yasuhisa Ano
exaly +5 more sources
Hop Phytochemicals and Their Potential Role in Metabolic Syndrome Prevention and Therapy [PDF]
Molecules, 2017 Historically, hop cones (Humulus lupulus) have been used since ancient times as a remedy for many ailments and, as a source of polyphenols and bitter acids, is very effective in the treatment of metabolic syndrome (MS).
Pavel Dostálek +2 more
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Journal of Functional Foods, 2023 Matured hop bitter acids (MHBA), produced by aging the hops used to make beer, activate the vagus nerve via bitter taste receptors and improve depression and cognitive function in mice. However, researchers have not investigated their effects on human autonomic nerves. This crossover study aimed to investigate the association between MHBA and the vagus
Satoshi Umeda, Yasuhisa Ano
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The relationship between the effect of matured hop extract and physical activity on reducing body fat: re-analysis of data from a randomized, double-blind, placebo-controlled parallel group study [PDF]
Nutrition Journal, 2018 Background We recently reported that successive ingestion of matured hop extract (MHE), produced by oxidation of hops, results in a reduction of body fat in healthy overweight participants.
Shigeo Suzuki +5 more
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Iso-α-acids and matured hop bitter acids in beer improve obesity-induced cognitive impairment
Bioscience, Biotechnology and Biochemistry, 2019 ABSTRACT Dementia and cognitive decline have become public health issues worldwide and life-style-related diseases and obesity have recently been reported as key risk factors. We have recently demonstrated that short-term administration of iso-α-acids (IAAs), hop-derived bitter components of beer, improves spatial and object recognition ...
Tatsuhiro Ayabe, Yasuhisa Ano
exaly +3 more sources
Matured Hop Bittering Components Induce Thermogenesis in Brown Adipose Tissue via Sympathetic Nerve Activity. [PDF]
PLoS ONE, 2015 Obesity is the principal symptom of metabolic syndrome, which refers to a group of risk factors that increase the likelihood of atherosclerosis. In recent decades there has been a sharp rise in the incidence of obesity throughout the developed world. Iso-
Yumie Morimoto-Kobayashi +7 more
doaj +2 more sources
An Updated Review of the Genus Humulus: A Valuable Source of Bioactive Compounds for Health and Disease Prevention. [PDF]
Plants (Basel), 2022 Carbone K, Carbone K, Gervasi F.
europepmc +1 more source