MRI‐based radiomics model for predicting VEGFA expression and prognosis in lower‐grade glioma
Abstract Background Gliomas are the most common primary tumors of the central nervous system. Their treatment remains highly challenging, with high rates of associated disability and mortality. Conventional prognostic indicators no longer adequately satisfy the clinical demands of precision medicine.
Kun Zhao +10 more
wiley +1 more source
Hypoxia-targeted BOLD MRI signal heterogeneity as a complementary metric for glioblastoma characterization: a pilot study. [PDF]
Zerweck L +13 more
europepmc +1 more source
Transverse Relaxation Time Constant of Cystathionine in Human Glioma at 3 T
ABSTRACT Purpose Cystathionine (Cth) has emerged as a promising biomarker for identifying 1p/19q codeleted gliomas. However, little is known about the T2 relaxation time constant of Cth in gliomas. The aim of this study was to measure the T2 of Cth in vivo in glioma and compare it to the T2s of other metabolites at 3 T.
Dinesh K. Deelchand +6 more
wiley +1 more source
Comparison of the normalized cerebral blood volume (CBV) between different models and evaluation of the efficacy of gadolinium leakage in evaluating preoperative adult-type gliomas. [PDF]
Wang C +6 more
europepmc +1 more source
We evaluated how confounding effects from fluid, macromolecules and T1 relaxation impact the performance of APTw and NOEw metrics for noninvasive glioma classification at 3 T. Corrected APTw metrics showed the highest discriminations of IDH‐mutant from wild‐type gliomas (AUC = 0.94–0.96), whereas NOEw metrics did not differ between groups.
Capucine Cadin +15 more
wiley +1 more source
Citric Acid Cycle Genes and Nutrigenetics. [PDF]
Vesnina A +3 more
europepmc +1 more source
We present a scalable, cell‐free, and straightforward NADH‐coupled CheA ATPase assay for quickly screening potential bacterial chemoeffectors and integrate it into a pipeline to identify both the chemoeffectors and their corresponding chemoreceptors in Pseudomonas parafulva, enabling systematic exploration of chemotactic sensing.
Rui Cui +4 more
wiley +1 more source
Isocitrate Dehydrogenases Idh1 and Idh2 Regulate Pronephric Morphogenesis in <i>Xenopus laevis</i>. [PDF]
Lee HK, Lee H, Kim C, Lee HS.
europepmc +1 more source
Introducing a phosphoketolase pathway into Bacillus methanolicus enhances methanol‐to‐biomass yields by 18%–24% and reduces CO2 evolution by up to 12%. Coupled with a tunable expression system, this work demonstrates improved carbon conservation and expands metabolic engineering strategies for methylotrophs.
Yael J. Toporek +6 more
wiley +1 more source
Evidence for ecological adaptation of reductive citric acid and reverse oxidative citric acid cycles based on a survey of genomes from autotrophic <i>Bacteria</i>. [PDF]
Scott KM +20 more
europepmc +1 more source

