Results 191 to 200 of about 358,941 (349)
DNA methyltransferase inhibitors in hematological malignancies and solid tumors
International Journal of Cancer, Volume 158, Issue 2, Page 433-461, 15 January 2026.Abstract Epigenetic modifications such as DNA methylation play a fundamental role in oncogenesis and the progression of neoplasms neoplasias. DNA methyltransferase inhibitors (DNMTi) constitute a family of therapeutic agents that impede the methylation at the 5‐position on cytosine nucleotides, thereby modulating the epigenetic regulation of tumor ...
Valentin Wenger +3 more
wiley +1 more source
Magnetic Resonance in Medicine, Volume 95, Issue 1, Page 4-19, January 2026.Abstract Purpose Metabolite concentrations are valuable biomarkers in brain tumors (BTs). However, absolute quantification of metabolites using MR spectroscopy requires a correction of water relaxation using time‐consuming quantitative MRI (qMRI) sequences in addition to a lengthy two‐dimensional spectroscopic water‐reference acquisition.
Dennis C. Thomas +5 more
wiley +1 more source
Biogenesis of Organelles and Membrane Proteins. [PDF]
, 1988 Harmey, Matthew A. +3 more
core +1 more source
A data‐driven algorithm to determine 1H‐MRS basis set composition
Magnetic Resonance in Medicine, Volume 95, Issue 1, Page 20-37, January 2026.Abstract Purpose Metabolite amplitude estimates derived from linear combination modeling of MR spectra depend on the precise list of constituent metabolite basis functions used (the “basis set”). The absence of clear consensus on the “ideal” composition or objective criteria to determine the suitability of a particular basis set contributes to the poor
Christopher W. Davies‐Jenkins +5 more
wiley +1 more source
Magnetic Resonance Spectroscopy of Cystathionine and 2‐Hydroxyglutarate in Brain Tumors
NMR in Biomedicine, Volume 39, Issue 1, January 2026.Cystathionine and 2‐hydroxyglutarate were evaluated in 38 glioma patients with TE 97ms PRESS at 3T. Cystathionine level was significantly higher in IDH‐mutant 1p/19q‐codeleted gliomas than in IDH‐mutant non‐codeleted gliomas (p = 0.002). The sensitivity and specificity of the cystathionine measures with respect to 1p/19q status were 0.8 and 0.79, while
Changho Choi +17 more
wiley +1 more source
Comparing Isocitrate Dehydrogenase Inhibitors with Procarbazine, Lomustine, and Vincristine Chemotherapy for Oligodendrogliomas. [PDF]
Cancers (Basel)Duran G +13 more
europepmc +1 more source
The isocitrate dehydrogenases of Acinetobacter lwoffi. Studies on the regulation of nicotinamide–adenine dinucleotide phosphate-linked isoenzyme [PDF]
, 1973 Colin H. Self +2 more
openalex +1 more source