Results 181 to 190 of about 190,806 (273)

Iron and Other Metal Ions in Human Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley   +1 more source

Mutant Isocitrate Dehydrogenase 1 Sensitizes Intrahepatic Cholangiocarcinoma Cells to MDM2 Inhibitors. [PDF]

Cancer Res Commun
Liu CT, Su YY, Chiang NJ, Li CF, Ma YC, Chang KC, Hung YH, Hung WC, Chen LT.   +8 more
europepmc   +1 more source

A State‐Resolved Single‐Cell and Spatial Atlas Reveals IDH‐Associated Differences in Malignant and Immune Architecture in Diffuse Glioma

MedComm, Volume 7, Issue 10, October 2026.
Single‐cell and spatial transcriptomic profiling of 69 adult‐type diffuse gliomas revealed seven recurrent malignant cell states. GBMs were enriched for astrocyte‐like progenitor, hypoxic, and proliferative states, with higher T‐ and myeloid‐cell infiltration but transcriptional immune suppression.
Ashraf Zaman, Emily Holton, Madhavi Pandya, Genevieve Shillington, Cecile Escher, Kavitha Krishna Sudhakar, Agota Tuzesi, Ashish Mehta, Eric Lam, Rachael Zekanovic, Michael Sughrue, Charlie Teo, Jacky Yeung, Walter Muskovic, Joseph E. Powell   +14 more
wiley   +1 more source

Fluorinated Derivatives of AG-881 for Positron Emission Tomography Detection of Mutated Isocitrate Dehydrogenase 1. [PDF]

Pharmaceuticals (Basel)
Lai TH, Dukić-Stefanović S, Deuther-Conrad W, Maisonial-Besset A, Teodoro R, Toussaint M, Wenzel B.   +6 more
europepmc   +1 more source

ON THE MECHANISM OF THE ACONITASE AND ISOCITRIC DEHYDROGENASE REACTIONS

Journal of Biological Chemistry, 1957
S, ENGLARD, S P, COLOWICK
openaire   +2 more sources

Glutamine Metabolism in Health and Diseases

MedComm, Volume 7, Issue 10, October 2026.
Glutamine metabolism acts as a metabolic hub connecting cellular stress adaptation, immune regulation, and disease development. Through regulating energy production, biosynthesis, redox balance, and nitrogen metabolism, glutamine supports cellular homeostasis under physiological and pathological conditions.
Yi Ding, Fan Tong, Jing Zeng, Chun‐Ping Cui   +3 more
wiley   +1 more source

Corrigendum to: The role of vorasidenib in the treatment of isocitrate dehydrogenase-mutant glioma. [PDF]

Neuro Oncol
europepmc   +1 more source

A Case of Multicentric Isocitrate Dehydrogenase-Wildtype Glioblastoma With Divergent Clonal Evolution. [PDF]

Cureus
Shibuya N, Higa N, Akahane T, Yonezawa H, Kirishima M, Tanimoto A, Hanaya R.   +6 more
europepmc   +1 more source

Some properties of yeast isocitrate dehydrogenase [PDF]

Biochemical Journal, 1972
openaire   +2 more sources

Feasibility of Spin‐ and Gradient‐Echo Dynamic Susceptibility Contrast MRI for Microvascular Characterization at 7 Tesla

NMR in Biomedicine, Volume 39, Issue 10, October 2026.
Spin‐ and‐gradient‐echo DSC MRI at 7 T allows for characterization of the microvasculature at an improved resolution and a reduced gadolinium‐based contrast agent dosage while maintaining increased vascular contrast. Ratios between normal‐appearing gray matter and white matter for relative cerebral blood volume and vessel size estimates were similar ...
Karen N. van der Werff, Daniëlle van Dorth, Krishnapriya Venugopal, Esther A. H. Warnert, Dirk H. J. Poot, Frans M. Vos, Marion Smits, Stefan Klein, C. Chad Quarles, Juan A. Hernandez‐Tamames, Johan A. F. Koekkoek, Jeroen de Bresser, Matthias J. P. van Osch   +12 more
wiley   +1 more source