Results 161 to 170 of about 403,859 (288)

Clinical and Genetic Landscape of Glioblastoma, IDH‐Wildtype With FGFR Gene Family Alterations

Cancer Science, Volume 117, Issue 5, Page 1455-1468, May 2026.
We analyzed 1076 cases of glioblastoma, IDH‐wildtype (GBM, IDH‐wt) using the C‐CAT genomic database to clarify the clinical and genetic features of FGFR alterations. FGFR::TACC fusions and FGFR1 mutations were identified in distinct subsets and were associated with unique co‐mutation patterns.
Yasuhito Kegoya, Yoshihiro Otani, Ryo Mizuta, Ryosuke Ikemachi, Mako Kamiura, Joji Ishida, Shinichi Toyooka, Daisuke Ennishi, Shuta Tomida, Shota Tanaka   +9 more
wiley   +1 more source

Endophytic Biostimulant Pyrroloquinoline Quinone Enhances Banana Growth and Primes Immunity Against Fusarium Wilt

Physiologia Plantarum, Volume 178, Issue 3, May/June 2026.
ABSTRACT Pyrroloquinoline quinone (PQQ) is a redox cofactor derived from prokaryotes that participates in various biological processes involving dehydrogenase enzymes. Previous field trials identified a PQQ‐producing endophyte, Burkholderia seminalis 869T2, which enhances banana growth and reduces Fusarium wilt incidence from 24.5% to 3.4%.
Shih‐Hsun Walter Hung, Man‐Yun Yu, Chia‐Ho Liu, Tsai‐Ching Huang, Jian‐Hau Peng, Nai‐Yun Jang, Chih‐Horng Kuo, Yu‐Liang Yang, Ying‐Ning Ho, En‐Pei Isabel Chiang, Hau‐Hsuan Hwang, Chieh‐Chen Huang   +11 more
wiley   +1 more source

Contrasting Effects of Chronic Glucokinase Activation and Inhibition on Pancreatic Beta‐Cell Function

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
In the non‐diabetic beta‐cell (top left) activation of glucokinase (bottom left) leads to inhibition of mitochondrial metabolism and thereby impairs insulin secretion. The effect is similar to that of chronic hyperglycaemia as seen in the diabetic beta‐cell (top right).
Matthew Lloyd, Natascia Vedovato, Samuel J. Mullan, Alice Elphick, Aerin J. Dumenil, Chantal Rufer, Alexandra C. Title, Burcak Yesildag, Elizabeth Haythorne, Frances M. Ashcroft   +9 more
wiley   +1 more source

Biosynthesis Of Glyoxysomal Enzymes In Neurospora Crassa [PDF]

, 1982
Flavell R. B., Frevert J., Fritz Miller, Gerhardt B., Herbert Desel, Johanson R. A., Kanarek L., Kindl, KOLLER W., Michael Janes, Mukkerjee A., Novikoff A. B., Richard Zimmermann, Riezman H., Srere P. A., Theimer R. R., Thorne C. J. R., Walter Neupert   +17 more
core   +1 more source

Isocitrate dehydrogenase mutations suppress STAT1 and CD8+ T cell accumulation in gliomas

Journal of Clinical Investigation, 2017
Gary Kohanbash, Diego A. Carrera, S. Shrivastav, Brian J. Ahn, Naznin Jahan, T. Mazor, Zinal S Chheda, Kira M. Downey, P. Watchmaker, Casey Beppler, R. Warta, N. Amankulor, C. Herold‐Mende, J. Costello, H. Okada   +14 more
semanticscholar   +1 more source

Inhibitors of mutant isocitrate dehydrogenase for isocitrate dehydrogenase-mutant gliomas: A new standard of care?

Glioma
Emilie Le Rhun, Zhong-ping Chen, Michael Weller   +2 more
doaj   +1 more source

Isocitrate Dehydrogenase Mutation and (R)-2-Hydroxyglutarate: From Basic Discovery to Therapeutics Development.

Annual Review of Biochemistry, 2017
L. Dang, Shinsan M. Su
semanticscholar   +1 more source

Isocitrate dehydrogenase 1 ( IDH1 ) [PDF]

Science-Business eXchange, 2014
openaire   +2 more sources

Isocitrate dehydrogenase‐mutant glioma: Evolving clinical and therapeutic implications

Cancer, 2017
Julie J. Miller, H. Shih, O. Andronesi, D. Cahill   +3 more
semanticscholar   +1 more source

Clinical advancement in the management of mutant isocitrate dehydrogenase (<i>IDH</i>) cancers. [PDF]

EJC Suppl
Bridgewater J, Tabatabai G, Macarulla T, Stacchiotti S.   +3 more
europepmc   +1 more source