Results 201 to 210 of about 358,941 (349)

NRF2 signalling in cytoprotection and metabolism

British Journal of Pharmacology, Volume 183, Issue 1, Page 101-114, January 2026.
The KEAP1‐NRF2 system plays a central role in cytoprotection in defence mechanisms against oxidative stress. The KEAP1‐NRF2 system has been regarded as a sulfur‐utilizing cytoprotective mechanism, because KEAP1 serves as a biosensor for electrophiles by using its reactive thiols and NRF2 is a transcriptional factor regulating genes involved in sulfur ...
Shohei Murakami, Yusuke Kusano, Keito Okazaki, Takaaki Akaike, Hozumi Motohashi   +4 more
wiley   +1 more source

Adaptation of Drosophila enzymes to temperature - I. Acetylcholinesterase and NADP-dependent isocitrate-dehydrogenase.

, 1978
S. Alahiotis, E. Berger
openalex   +1 more source

Non‐canonical nitric oxide signalling and DNA methylation: Inflammation induced epigenetic alterations and potential drug targets

British Journal of Pharmacology, Volume 183, Issue 1, Page 24-39, January 2026.
Abstract DNA methylation controls DNA accessibility to transcription factors and other regulatory proteins, thereby affecting gene expression and hence cellular identity and function. As epigenetic modifications control the transcriptome, epigenetic dysfunction is strongly associated with pathological conditions and ageing.
Christopher H. Switzer
wiley   +1 more source

3D spatial sampling to quantify morphologic heterogeneity in isocitrate dehydrogenase-wildtype glioblastoma. [PDF]

J Neuropathol Exp Neurol
Voong V, Beccari S, Hashemi E, Kriener B, Mathur R, Lafontaine M, Shai A, Lupo JM, Chang EF, Hervey-Jumper SL, Berger MS, Waszak SM, Costello JF, Phillips JJ.   +13 more
europepmc   +1 more source

Programmed Death Ligand 1 Is a Negative Prognostic Marker in Recurrent Isocitrate Dehydrogenase-Wildtype Glioblastoma

, 2018
Drew Pratt, Gifty Dominah, Graham P. Lobel, Arnold Obungu, John Lynes, Victoria Sánchez, Nicholas Adamstein, Xiang Wang, Nancy A. Edwards, Tianxia Wu, Dragan Maric, Amber Giles, Mark R. Gilbert, Martha Quezado, Edjah K. Nduom   +14 more
openalex   +2 more sources

Mitochondrial localization of a NADR-dependent isocitrate dehydrogenase isoenzyme by using the green fluorescent protein as a marker [PDF]

, 1998
Susana Gálvez, O. García Roché, E. Bismuth, Spencer C. Brown, Pierre Gadal, Michael Hodges   +5 more
openalex   +1 more source

Unravelling the Significance of Phosphoenolpyruvate Carboxylase in Phosphate Starvation Responses

Plant, Cell &Environment, Volume 49, Issue 1, Page 177-192, January 2026.
ABSTRACT Low phosphate availability is a major concern for agriculture. Plants develop a plethora of responses to improve phosphate acquisition, known as phosphate starvation responses (PSR). Among them, the induction of phosphoenolpyruvate carboxylase (PEPC) has been described in many plants. However, most studies have been conducted in the absence of
Jesús Pérez‐López, Clara de la Osa, Jacinto Gandullo, Nora Gigli‐Bisceglia, Inmaculada Coleto, Ana Belén Feria, Cristina Echevarría, Christa Testerink, Daniel Marino, Sofía García‐Mauriño, José A. Monreal   +10 more
wiley   +1 more source

A novel isocitrate dehydrogenase 1 G131D mutation in glioblastoma

Chinese Medical Journal, 2021
Lei-Ming Wang, Chao Song, Ying-Xue Li, Xue-Dong Zhang, Yu-Hang Ji, Wen-Juan Wen, Peng Lyu   +6 more
doaj   +1 more source

Poor diagnostic value of isocitrate dehydrogenase 1 R132H immunohistochemistry for determination of isocitrate dehydrogenase 1 status in patients with glioblastoma. [PDF]

Surg Neurol Int
Faried A, Hadi EJ, Agustina H.
europepmc   +1 more source

Control of NADP⁺‐specific isocitrate dehydrogenase from acinetobacter by nucleotides [PDF]

, 1976
H.‐P. Kleber, H. Aurich
openalex   +1 more source