Results 71 to 80 of about 179,953 (145)

Systemic Treatments for Recurrent or Metastatic Sinonasal Carcinomas: A Retrospective Multicenter Study

Head &Neck, Volume 48, Issue 10, Page 2810-2820, October 2026.
ABSTRACT Introduction Sinonasal cancers are rare and heterogeneous and pose a therapeutic challenge at an advanced stage due to the lack of data on appropriate systemic management. Methods This retrospective multicenter study analyzed 83 patients with recurrent or metastatic sinonasal carcinomas ineligible for curative treatment, treated in France ...
Marie Degrange, Mathilde Morisseau, Justin Michel, Thibaut Reverdy, Sylvain Morinière, Amaury Daste, Maxime Humbert, Caroline Viala, Pauline Corbaux, Tiffany Darbas, François‐Régis Ferrand, Valentin Favier, Camille Evrard, Diane Evrard, Delphine Farneti, Sarah Betrian‐Lagarde, Victor Sarradin   +16 more
wiley   +1 more source

Mitotic index is (still) important for grading isocitrate dehydrogenase (IDH)-mutant astrocytoma. [PDF]

Neuro Oncol, 2023
Roberts KF, Dahiya SM.
europepmc   +1 more source

A State‐Resolved Single‐Cell and Spatial Atlas Reveals IDH‐Associated Differences in Malignant and Immune Architecture in Diffuse Glioma

MedComm, Volume 7, Issue 10, October 2026.
Single‐cell and spatial transcriptomic profiling of 69 adult‐type diffuse gliomas revealed seven recurrent malignant cell states. GBMs were enriched for astrocyte‐like progenitor, hypoxic, and proliferative states, with higher T‐ and myeloid‐cell infiltration but transcriptional immune suppression.
Ashraf Zaman, Emily Holton, Madhavi Pandya, Genevieve Shillington, Cecile Escher, Kavitha Krishna Sudhakar, Agota Tuzesi, Ashish Mehta, Eric Lam, Rachael Zekanovic, Michael Sughrue, Charlie Teo, Jacky Yeung, Walter Muskovic, Joseph E. Powell   +14 more
wiley   +1 more source

Feasibility of Spin‐ and Gradient‐Echo Dynamic Susceptibility Contrast MRI for Microvascular Characterization at 7 Tesla

NMR in Biomedicine, Volume 39, Issue 10, October 2026.
Spin‐ and‐gradient‐echo DSC MRI at 7 T allows for characterization of the microvasculature at an improved resolution and a reduced gadolinium‐based contrast agent dosage while maintaining increased vascular contrast. Ratios between normal‐appearing gray matter and white matter for relative cerebral blood volume and vessel size estimates were similar ...
Karen N. van der Werff, Daniëlle van Dorth, Krishnapriya Venugopal, Esther A. H. Warnert, Dirk H. J. Poot, Frans M. Vos, Marion Smits, Stefan Klein, C. Chad Quarles, Juan A. Hernandez‐Tamames, Johan A. F. Koekkoek, Jeroen de Bresser, Matthias J. P. van Osch   +12 more
wiley   +1 more source

A Time‐Calibrated Phylogeny and Historical Biogeography of Leptoceridae (Trichoptera): Diversification Shaped by Gondwanan Fragmentation and Conflicting Evidence for the Family's Origin

Journal of Biogeography, Volume 53, Issue 10, October 2026.
ABSTRACT Aim Leptoceridae is the second most diverse caddisfly family, spreading across all biogeographical regions but with a higher species richness in the Oriental region; nevertheless, the Afrotropical, Austral and Neotropical regions have greater genera diversity and endemicity.
Everton S. Dias, Albane Vilarino, Adolfo R. Calor, Pitágoras C. Bispo   +3 more
wiley   +1 more source

Isocitrate dehydrogenase mutations in myeloid malignancies

, 2017
Alterations to genes involved in cellular metabolism and epigenetic regulation are implicated in the pathogenesis of myeloid malignancies. Recurring mutations in isocitrate dehydrogenase (IDH) genes are detected in approximately 20% of adult patients ...
S M Chan, C D DiNardo, Pollyea, D A, Swords, R, DiNardo, C D, Medeiros, B C, Chan, S M, A T Fathi, Fathi, A T, B C Medeiros, D A Pollyea, R Swords   +11 more
core   +1 more source

Optimize treatment approaches in isocitrate dehydrogenase (IDH) mutant gliomas: open issues. [PDF]

Neuro Oncol, 2023
Rudà R.
europepmc   +1 more source

Naturopathic Treatment of Grade III Oligodendroglioma With Progression to Grade IV Isocitrate Dehydrogenase (IDH)-Mutant Astrocytoma and the Development of Spinal Gliomatosis. [PDF]

Cureus, 2023
Terrani KF, Reynolds CD, Rogers SN.
europepmc   +1 more source

Glioma immunotherapy enhancement and CD8-specific sialic acid cleavage by isocitrate dehydrogenase (IDH)-1. [PDF]

Oncogene, 2023
Cordner R, Jhun M, Panwar A, Wang H, Gull N, Murali R, McAbee JH, Mardiros A, Sanchez-Takei A, Mazer MW, Fan X, Jouanneau E, Yu JS, Black KL, Wheeler CJ.   +14 more
europepmc   +1 more source

Radiological Prediction of Isocitrate Dehydrogenase (IDH) Mutational Status and Pathological Verification for Lower-Grade Astrocytomas. [PDF]

Cureus, 2022
Yano H, Ikegame Y, Miwa K, Nakayama N, Maruyama T, Ikuta S, Yokoyama K, Muragaki Y, Iwama T, Shinoda J.   +9 more
europepmc   +1 more source