Results 151 to 160 of about 693,247 (202)

Glutamine Metabolism in Health and Diseases

MedComm, Volume 7, Issue 10, October 2026.
Glutamine metabolism acts as a metabolic hub connecting cellular stress adaptation, immune regulation, and disease development. Through regulating energy production, biosynthesis, redox balance, and nitrogen metabolism, glutamine supports cellular homeostasis under physiological and pathological conditions.
Yi Ding, Fan Tong, Jing Zeng, Chun‐Ping Cui   +3 more
wiley   +1 more source

Feasibility of Spin‐ and Gradient‐Echo Dynamic Susceptibility Contrast MRI for Microvascular Characterization at 7 Tesla

NMR in Biomedicine, Volume 39, Issue 10, October 2026.
Spin‐ and‐gradient‐echo DSC MRI at 7 T allows for characterization of the microvasculature at an improved resolution and a reduced gadolinium‐based contrast agent dosage while maintaining increased vascular contrast. Ratios between normal‐appearing gray matter and white matter for relative cerebral blood volume and vessel size estimates were similar ...
Karen N. van der Werff, Daniëlle van Dorth, Krishnapriya Venugopal, Esther A. H. Warnert, Dirk H. J. Poot, Frans M. Vos, Marion Smits, Stefan Klein, C. Chad Quarles, Juan A. Hernandez‐Tamames, Johan A. F. Koekkoek, Jeroen de Bresser, Matthias J. P. van Osch   +12 more
wiley   +1 more source

Isocitrate Dehydrogenase Mutation Assessment in Human Glioma Using Desorption Electrospray Ionization-Multiple Reaction Monitoring. [PDF]

Anal Chem
Shahi M, Garcia DM, Quiñones-Hinojosa A, Cooks RG.   +3 more
europepmc   +1 more source

A Multi‐Scale Computational Framework for Anti‐Persister Tuberculosis Drug Discovery

Chemical Biology &Drug Design, Volume 108, Issue 4, October 2026.
This review presents an integrated QSAR–scaffold design–docking–MD framework for discovering anti‐persister tuberculosis agents active in dormant granuloma‐like conditions. By targeting Mtb bioenergetics and prioritising dual NDH‐2/cytochrome bd oxidase inhibition, the workflow advances rational design of candidates with higher resistance barriers ...
Said Moshawih, Anguraj Moulishankar, Chee Yan Choo, Khang Wen Goh, Chrismawan Ardianto, Azam Che Idris, Long Chiau Ming   +6 more
wiley   +1 more source

Predicting isocitrate dehydrogenase mutation status in acute myeloid leukemia from gene expression profiles by machine learning. [PDF]

NAR Genom Bioinform
Jung I, Vitte AL, Chuffart F, Chevalier S, Mossuz P, Khochbin S, Bourova-Flin E.   +6 more
europepmc   +1 more source

Chromatin-regulating genes are associated with postoperative prognosis and isocitrate dehydrogenase mutation in astrocytoma. [PDF]

Ann Transl Med, 2020
Zhang K, Zhao H, Zhang K, Hua C, Qin X, Xu S.   +5 more
europepmc   +1 more source

Clinical and Prognostic Implications of Isocitrate Dehydrogenase Mutation in Gliomas Within a Latin American Public Oncology System: Insights From a Retrospective Panamanian Cohort. [PDF]

Cureus
Palma-García F, Abrego A, O Neill A, Lorenzo-Luaces R, Salgado M, Chong P, Castillo J, Arauz RE.   +7 more
europepmc   +1 more source

Correlation between Isocitrate Dehydrogenase Mutation and Immunohistochemical Expression of DNA Mismatch Repair Proteins in the Prognosis of Gliomas. [PDF]

Asian Pac J Cancer Prev
Saeed NM, Rashed H, Hussein S, Al-Karamany AS, Elmesallamy W, Waley AB, Obaya AA, Gharieb SA, Amgd K, Ibrahim SM, Abdelhamid MI, Khamis T, Mohamed AH.   +12 more
europepmc   +1 more source

Prediction of isocitrate dehydrogenase mutation status in WHO grade II glioma by diffusion kurtosis imaging. [PDF]

Pol J Radiol
Wu W, Zhang H.
europepmc   +1 more source

Using partially shared radiomics features to simultaneously identify isocitrate dehydrogenase mutation status and epilepsy in glioma patients from MRI images. [PDF]

Sci Rep
Wang Y, Gao A, Yang H, Bai J, Zhao G, Zhang H, Song Y, Wang C, Zhang Y, Cheng J, Yang G.   +10 more
europepmc   +1 more source