Results 31 to 40 of about 57,138 (236)

Integrated Bioinformatics-Based Subtractive Genomics Approach to Decipher the Therapeutic Drug Target and Its Possible Intervention against Brucellosis

Bioengineering, 2022
Brucella suis, one of the causative agents of brucellosis, is Gram-negative intracellular bacteria that may be found all over the globe and it is a significant facultative zoonotic pathogen found in livestock.
Kanwal Khan, Munirah Sulaiman Othman Alhar, Muhammad Naseer Abbas, Syed Qamar Abbas, Mohsin Kazi, Saeed Ahmad Khan, Abdul Sadiq, Syed Shams ul Hassan, Simona Bungau, Khurshid Jalal   +9 more
doaj   +1 more source

Methylcitrate cycle defines the bactericidal essentiality of isocitrate lyase for survival of Mycobacterium tuberculosis on fatty acids. [PDF]

Proc Natl Acad Sci U S A, 2014
Eoh H, Rhee KY.
europepmc   +2 more sources

Isocitrate Lyase in Green Leaves [PDF]

Plant Physiology, 1973
Isocitrate lyase (EC 4.1.3.1) has been demonstrated in crude dialyzed extracts of healthy spinach (Spinacia oleracea) leaves from commercial sources and wheat (Triticum aestivum) and maize (Zea mays) leaves stored in darkness in the cold room for 1 week.
H R, Godavari, S S, Badour, E R, Waygood
openaire   +2 more sources

Aconitate decarboxylase 1 participates in the control of pulmonary Brucella infection in mice.

PLoS Pathogens, 2021
Brucellosis is one of the most widespread bacterial zoonoses worldwide. Here, our aim was to identify the effector mechanisms controlling the early stages of intranasal infection with Brucella in C57BL/6 mice.
Aurore Demars, Armelle Vitali, Audrey Comein, Elodie Carlier, Abdulkader Azouz, Stanislas Goriely, Justine Smout, Véronique Flamand, Mégane Van Gysel, Johan Wouters, Jan Abendroth, Thomas E Edwards, Arnaud Machelart, Eik Hoffmann, Priscille Brodin, Xavier De Bolle, Eric Muraille   +16 more
doaj   +1 more source

Biochemical adaptation of Weigela florida «Variegata» Bunge A. D. C. microclones to salt- and copper induced stress [PDF]

Сибирский лесной журнал, 2017
Microclones of perennial shrub Weigela florida «Variegata» were prepared, adapted to the conditions of salinity and increased copper ions proportion during the three-step in vitro experiment.
O. A. Zemlyanukhina, V. N. Kalaev, V. S. Voronina, A. T. Eprintsev   +3 more
doaj   +1 more source

The Methylcitrate Cycle and Its Crosstalk with the Glyoxylate Cycle and Tricarboxylic Acid Cycle in Pathogenic Fungi

Molecules, 2023
In fungi, the methylcitrate cycle converts cytotoxic propionyl-coenzyme A (CoA) to pyruvate, which enters gluconeogenesis. The glyoxylate cycle converts acetyl-CoA to succinate, which enters gluconeogenesis.
Zhicheng Huang, Qing Wang, Irshad Ali Khan, Yan Li, Jing Wang, Jiaoyu Wang, Xiaohong Liu, Fucheng Lin, Jianping Lu   +8 more
doaj   +1 more source

Effect of Metabolic Regulators and Aeration on Isocitric Acid Synthesis by Yarrowia lipolytica Grown on Ester-Aldehyde Fraction

Fermentation, 2021
Isocitric acid (ICA) has found wide application in medicine as a promising compound with powerful antioxidant activity to combat oxidative stress. In the known microbiological processes of ICA production by non-conventional yeast Yarrowia lipolytica, the
Svetlana V. Kamzolova, Igor G. Morgunov
doaj   +1 more source

Studies on activities of PTA, AK, ICL and MS enzymes involved in the acetate metabolism of Corynebacterium glutamicum

浙江大学学报. 农业与生命科学版, 2003
The four enzymes of acetate kinase (AK), phosphotransacetylase (PTA), isocitrate lyase (ICL) and malate systhase (MS) which are involved in the acetate metabolism of Corynebacterium glutamicum have been developed in their assay methods.
RUAN Hong, XUAN Ri-rong
doaj   +1 more source

¹³C metabolic flux analysis identifies an unusual route for pyruvate dissimilation in mycobacteria which requires isocitrate lyase and carbon dioxide fixation.

PLoS Pathogens, 2011
Mycobacterium tuberculosis requires the enzyme isocitrate lyase (ICL) for growth and virulence in vivo. The demonstration that M. tuberculosis also requires ICL for survival during nutrient starvation and has a role during steady state growth in a ...
Dany J V Beste, Bhushan Bonde, Nathaniel Hawkins, Jane L Ward, Michael H Beale, Stephan Noack, Katharina Nöh, Nicholas J Kruger, R George Ratcliffe, Johnjoe McFadden   +9 more
doaj   +1 more source

Cloning and expression of isocitrate lyase from human round worm Strongyloides stercoralis

Parasite, 2000
A full length cDNA (1463 bp) encoding isocitrate lyase (EC 4.1.3.1) of Strongyloides stercoralis is described. The nucleotide sequence of this insert identified a cDNA coding for the isocitrate lyase.
Siddiqui A.A., Stanley C.S., Berk S.L.
doaj   +1 more source