Results 261 to 270 of about 66,610 (320)
ERK and AKT phosphorylation status in lung cancer and emphysema using nanocapillary isoelectric focusing. [PDF]
BMJ Open Respir Res, 2016 Crosbie PA +10 more
europepmc +1 more source
Advanced Materials, Volume 38, Issue 3, 13 January 2026.This study introduces glutathione‐stabilized gold nanoparticles for targeted lithium delivery (LiG‐AuNPs), enabling the controlled modulation of Glycogen Synthase Kinase‐3 (GSK‐3β). These non‐toxic, 2‐nm particles release lithium intracellularly, effectively inhibiting GSK‐3β in the brain without significant plasma lithium alterations.
Antonio Buonerba +20 more
wiley +1 more source
Capillary Isoelectric Focusing of Akt Isoforms Identifies Highly Dynamic Phosphorylation in Neuronal Cells and Brain Tissue. [PDF]
J Biol Chem, 2016 Schrötter S +2 more
europepmc +1 more source
Observation of Catalytic Variability of Single Enzyme Zeolitic Imidazole Framework‐8 Nanoparticles
Advanced Materials Interfaces, Volume 13, Issue 1, 7 January 2026.A microwell‐based fluorescence method characterizes the catalytic activity of single enzyme zeolitic imidazole framework‐8 (ZIF‐8) nanoparticles (NPs). Horseradish peroxidase (HRP) and bovine serum albumin (BSA) are loaded into ZIF‐8 NPs and reveal subpopulations of catalytic activity at single‐particle resolution.
Melissa C. D'Amaral +2 more
wiley +1 more source
Capillary isoelectric focusing of individual mitochondria. [PDF]
Anal Chem, 2011 Wolken GG, Kostal V, Arriaga EA.
europepmc +1 more source
Enrichment of Hypermethylated DNA on Chip for Cervical Cancer Detection
Advanced Materials Interfaces, Volume 13, Issue 1, 7 January 2026.A microfluidic chip coated with surface‐immobilized methyl binding domain 2 (MBD‐2) protein receptors, is able to bind hypermethylated DNA (hmDNA) from a cancer cell line selectively. Quantification by quantitative polymerase chain reaction (qPCR) shows a 30‐fold enrichment in cervical cancer target DNA.
Ruben W. Kolkman +7 more
wiley +1 more source
Combining high-throughput MALDI-TOF mass spectrometry and isoelectric focusing gel electrophoresis for virtual 2D gel-based proteomics. [PDF]
Methods, 2016 Lohnes K +5 more
europepmc +1 more source
Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.Abstract The incidence of Alzheimer's disease (AD) continues to increase, despite decades of effort to develop disease‐modifying therapies. In response, the National Institute on Aging (NIA) established the TaRget Enablement to Accelerate Therapy Development for Alzheimer's Disease (TREAT‐AD) centers to address the gap between basic research and ...
Timothy I. Richardson +8 more
wiley +1 more source