Results 231 to 240 of about 4,986,973 (317)

Observation of Catalytic Variability of Single Enzyme Zeolitic Imidazole Framework‐8 Nanoparticles

Advanced Materials Interfaces, Volume 13, Issue 1, 7 January 2026.
A microwell‐based fluorescence method characterizes the catalytic activity of single enzyme zeolitic imidazole framework‐8 (ZIF‐8) nanoparticles (NPs). Horseradish peroxidase (HRP) and bovine serum albumin (BSA) are loaded into ZIF‐8 NPs and reveal subpopulations of catalytic activity at single‐particle resolution.
Melissa C. D'Amaral, Jared M. D. King, Alana F. Ogata   +2 more
wiley   +1 more source

Enrichment of Hypermethylated DNA on Chip for Cervical Cancer Detection

Advanced Materials Interfaces, Volume 13, Issue 1, 7 January 2026.
A microfluidic chip coated with surface‐immobilized methyl binding domain 2 (MBD‐2) protein receptors, is able to bind hypermethylated DNA (hmDNA) from a cancer cell line selectively. Quantification by quantitative polymerase chain reaction (qPCR) shows a 30‐fold enrichment in cervical cancer target DNA.
Ruben W. Kolkman, Birgit M. M. Wever, Jeanne Elisabeth van Dongen, Annina P. van Splunter, Johan G. Bomer, Renske D. M. Steenbergen, Loes I. Segerink, Jurriaan Huskens   +7 more
wiley   +1 more source

Electro‐Conductive Silver‐Coated Polyamide‐Imide Membranes for Sustainable Water Treatment

Advanced Sustainable Systems, Volume 10, Issue 1, January 2026.
This study reports the development of a silver‐coated, electro‐conductive ultrafiltration membrane supported on polyamide‐imide. Using a simple and scalable spray‐coating method, the membrane achieved a high electrical conductivity of 2.215 × 10−5 S cm−1.
Zahra Zandi, Mehrasa Yassari, Mojtaba Mohseni, Hesam Jafarian, Mohsen Pilevar, Mahshid Mardani, Farah Rahman Omi, Mark Elliott, Ahmad Rahimpour, Matthias Wessling, Mostafa Dadashi Firouzjaei, Mohtada Sadrzadeh   +11 more
wiley   +1 more source

A Biologically Informed Vision‐Guided Framework for Interpretable T Cell Receptor–Epitope Binding Prediction

Advanced Science, Volume 13, Issue 4, 19 January 2026.
Integrating hierarchical physicochemical features via a bio‐inspired design, the DAISY framework robustly predicts T‐cell receptor binding, significantly outperforming state‐of‐the‐art models on unseen epitopes. It uniquely offers visual interpretability via Score‐CAM visualizations and profound clinical relevance, correlating with T‐cell expansion ...
Yajing Yuan, Junwei Chen, Yufang Zhang, Yitian Fang, Zhongcheng Fang, Yanyi Chu, Jiayi Li, Chen Zhang, Yuzhe Li, Dongqing Wei   +9 more
wiley   +1 more source

Simulation Insights into the Assembly of Polyplexes for RNA Delivery. [PDF]

Biomacromolecules
Lehnen JH, Moreno Herrero J, Haas H, Schmid F, Settanni G.   +4 more
europepmc   +1 more source

Boosting Nanofiltration Membrane Selectivity via Amine‐Polymer Additive Engineering for Efficient Lithium Extraction From Brine

Advanced Science, Volume 13, Issue 3, 14 January 2026.
A diffusion‐controlled interfacial polymerization strategy incorporating poly(allylamine) (PAA) into piperazine (PIP) solution enables precise tuning of amine monomer diffusion and polyamide (PA) network formation with trimesoyl chloride (TMC). The resulting nanofiltration membranes exhibit crumpled morphology, appropriate surface charge, and enhanced ...
Shaofan Duan, Shuai Jiang, Ping Xu, Zhan Li, Pengfei Zhang, Yanyan Liu, Atsushi Matsuoka, Yuqing Lin, Jie Shen, Kecheng Guan, Tomohisa Yoshioka, Hideto Matsuyama   +11 more
wiley   +1 more source

Reticular Chemistry: A Versatile Platform for Engineering Heterogenous Biocatalysts

Advanced Science, Volume 13, Issue 4, 19 January 2026.
Rational design of reticular‐based heterogeneous biocatalysts enables significant enhancement in enzyme activity recovery and even achieves catalytic performance beyond native enzymes. Abstract Reticular materials, including metal‐organic frameworks (MOFs), covalent organic frameworks (COFs), and hydrogen‐bonded organic frameworks (HOFs), have emerged ...
Si Liu, Peiji Deng, Qianfan Chen, Qijun Sun, Yanhan Wang, Hongyu Shi, Kang Liang   +6 more
wiley   +1 more source

pH guided pathways trigger tailoring of chiral luminescence in enantiomeric gold cluster assemblies. [PDF]

Chem Sci
Dutta C, Kumar J.
europepmc   +1 more source

Chitooligosaccharide assisted in the construction of pickering high internal phase emulsion near the isoelectric point of porcine plasma protein

Xiaocui Liu, Jianglan Yuan, Rui Chen, Jin-ying Lv, Zhuanzhuan Ma, Xu Kang   +5 more
openalex   +1 more source

Next‐generation Alzheimer's therapeutics: target assessment and enablement at the Indiana University School of Medicine–Purdue University TREAT‐AD Center

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract The incidence of Alzheimer's disease (AD) continues to increase, despite decades of effort to develop disease‐modifying therapies. In response, the National Institute on Aging (NIA) established the TaRget Enablement to Accelerate Therapy Development for Alzheimer's Disease (TREAT‐AD) centers to address the gap between basic research and ...
Timothy I. Richardson, Rebecca C. Klein, Kun Huang, Jie Zhang, Andrew D. Mesecar, Jeffrey L. Dage, Brent Clayton, Bruce T. Lamb, Alan D. Palkowitz   +8 more
wiley   +1 more source