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The introduction of isoflurane to clinical practice follows the search for a nonflammable, potent inhalation anesthetic which, above all, is chemically stable so as to resist biodegradation or attack by other chemicals. These attributes characterize isoflurane (Table 2).
Wendell C. Stevens, John G. Wade
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Stereoselectivity of Isoflurane in Adhesion Molecule Leukocyte Function-Associated Antigen-1 [PDF]
Background: Isoflurane in clinical use is a racemate of S- and R-isoflurane. Previous studies have demonstrated that the effects of S-isoflurane on relevant anesthetic targets might be modestly stronger (less than 2-fold) than R-isoflurane.
Bu, Weiming+3 more
core +9 more sources
Isoflurane for conscious sedation [PDF]
SummaryIsoflurane 0.5% in oxygen for conscious sedation was compared with placebo (oxygen) and with an equipotent concentration of nitrous oxide in oxygen, in patients scheduled for surgical removal of bilateral, similarly impacted lower third molars. The majority of patients were sedated with 0.5% isoflurane in oxygen and preferred it to both placebo ...
J. B. Rosenquist, M. R. C. Rodrigo
openaire +7 more sources
SummaryA comparison of the analgesic efficacy of Entonox (50% nitrous oxide in oxygen) and Entonox with 0.2% isofturane was made in 18 consenting mothers during the first stage of labour. The inhalational gases were self‐administered during contractions over a 3 h study period using a standard Entonox demand valve and breathing system.
M. A. Hasan, T. A. Thomas, M. Y. K. Wee
openaire +3 more sources
Isoflurane preconditioning inhibited isoflurane-induced neurotoxicity [PDF]
The commonly used inhaled anesthetic isoflurane has been shown to be both neuroprotective and neurotoxic in various cell cultures and animal models. We hypothesize that, like cerebral ischemia, isoflurane is inherently neurotoxic. Limited exposure of isoflurane provides neuroprotection via induction of endogenous neuroprotective mechanisms ...
Huafeng Wei+3 more
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Isoflurane on brain inflammation [PDF]
Brain inflammation may play an important role in the pathophysiology of early brain injury after subarachnoid hemorrhage (SAH). Our aim was to demonstrate brain inflammation development and to determine whether isoflurane, a clinically available volatile anesthetic agent, prevents brain inflammation after SAH.
Yu Hasegawa+5 more
openaire +4 more sources
The cerebrovascular effects of adrenaline, noradrenaline and dopamine infusions under propofol and isoflurane anaesthesia in sheep [PDF]
Publisher's copy made available with the permission of the publisher © Australian Society of AnaesthetistsInfusions of catecholamines are frequently administered to patients receiving propofol or isoflurane anaesthesia.
Fortin D.+5 more
core +2 more sources
Electroencephalogram of Healthy Horses During Inhaled Anesthesia. [PDF]
BackgroundPrevious study of the diagnostic validity of electroencephalography (EEG) to detect abnormalities in equine cerebral cortical function relied on the administration of various drugs for sedation, induction, and maintenance of general anesthesia ...
Aleman, MR+8 more
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The Effects of Changing from Isoflurane to Desflurane on the Recovery Profile during the Latter Part of Anesthesia [PDF]
It is not known whether changing from isoflurane to desflurane during the latter part of anesthesia shows early emergence and recovery in long surgery.
Baek, Chong-Wha+8 more
core +1 more source
Physostigmine and Methylphenidate Induce Distinct Arousal States During Isoflurane General Anesthesia in Rats [PDF]
BACKGROUND: Although emergence from general anesthesia is clinically treated as a passive process driven by the pharmacokinetics of drug clearance, agents that hasten recovery from general anesthesia may be useful for treating delayed emergence ...
Ba, Demba E+8 more
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