Results 1 to 10 of about 221,447 (295)
Ferroptosis contributes to isoflurane-induced neurotoxicity and learning and memory impairment
Cell Death Discovery, 2021 Ferroptosis is a novel type of programmed cell death, which is different from apoptosis and autophagic cell death. Recently, ferroptosis has been indicated to contribute to the in vitro neurotoxicity induced by isoflurane, which is one of the most common
Pengfei Liu
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A pilot study on midazolam sedation for murine echocardiography: A potential alternative to isoflurane anesthesia and awake imaging [PDF]
Physiological ReportsIsoflurane anesthesia is often used to facilitate murine echocardiography, but can suppress cardiac function. Awake imaging avoids pharmacological interference, but can induce sympathetic activation. In this Midazolam sedation.
Bart Jacobs +8 more
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Isoflurane aggravates pre-existing proteotoxicity in adult nematodes by suppressing mitochondrial fitness [PDF]
Scientific ReportsPost operative delirium (POD) is an acute complication, characterized by fluctuating attention and confusion, which may develop and persist into cognitive decline.
Tayir Elami +7 more
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Frontiers in Medicine, 2021 Objective: Surgery is the first line treatment of colorectal cancer (CRC). Anesthetic isoflurane may improve outcomes of cancer surgery. Herein, we investigated the effects of isoflurane on malignant behaviors of CRC cells and its underlying therapeutic ...
Zhe Cai, Liangyuan Suo, Zeqing Huang
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Isoflurane exposure for three hours triggers apoptotic cell death in neonatal macaque brain [PDF]
British Journal of Anaesthesia, 2017 Kazuma Noguchi +7 more
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Paired assessment of volatile anesthetic concentrations with synaptic actions recorded in vitro. [PDF]
PLoS ONE, 2008 The volatile anesthetic isoflurane poses a number of experimental challenges in the laboratory. Due to its rapid evaporation, the open conditions of most in vitro electrophysiological recording systems make the determination of actual isoflurane ...
Stuart J McDougall +5 more
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Stereoselectivity of isoflurane in adhesion molecule leukocyte function-associated antigen-1. [PDF]
PLoS ONE, 2014 Isoflurane in clinical use is a racemate of S- and R-isoflurane. Previous studies have demonstrated that the effects of S-isoflurane on relevant anesthetic targets might be modestly stronger (less than 2-fold) than R-isoflurane.
Weiming Bu +3 more
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Folia Histochemica et Cytobiologica, 2021 INTRODUCTION: Isoflurane anesthesia at the period of brain development can lead to neurotoxicity and long-term cognitive impairment. This study aimed to investigate the role of miR-497 on isoflurane-induced neurotoxicity.
Yuanyuan Que +5 more
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Isoflurane preconditioning inhibited isoflurane-induced neurotoxicity [PDF]
Neuroscience Letters, 2007 The commonly used inhaled anesthetic isoflurane has been shown to be both neuroprotective and neurotoxic in various cell cultures and animal models. We hypothesize that, like cerebral ischemia, isoflurane is inherently neurotoxic. Limited exposure of isoflurane provides neuroprotection via induction of endogenous neuroprotective mechanisms ...
Huafeng, Wei, Ge, Liang, Hui, Yang
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