Results 91 to 100 of about 317,847 (279)
A Mitochondrion-Targeted Antioxidant Ameliorates Isoflurane-Induced Cognitive Deficits in Aging Mice
PLoS ONE, 2015 Isoflurane possesses neurotoxicity and can induce cognitive deficits, particularly in aging mammals. Mitochondrial reactive oxygen species (mtROS) have been linked to the early pathogenesis of this disorder.
Jing Wu +8 more
semanticscholar +1 more source
Accurate molecular imaging of small animals taking into account animal models, handling, anaesthesia, quality control and imaging system performance [PDF]
, 2015 Small-animal imaging has become an important technique for the development of new radiotracers, drugs and therapies. Many laboratories have now a combination of different small-animal imaging systems, which are being used by biologists, pharmacists ...
Bankstahl, Jens +5 more
core +1 more source
Frontiers in Veterinary Science, 2019 Introduction: Tafonius is an anesthesia machine with computer-controlled monitor and ventilator. We compared the isoflurane fluctuations in the circuit with manual (MF) or computer-driven (CF) flowmeters, investigated the origin of the differences and ...
Mathieu Raillard +3 more
doaj +1 more source
Isoflurane depresses hippocampal CA1 glutamate nerve terminals without inhibiting fiber volleys
BMC Neuroscience, 2006 Background Anesthetic-induced CNS depression is thought to involve reduction of glutamate release from nerve terminals. Recent studies suggest that isoflurane reduces glutamate release by block of Na channels.
MacIver M Bruce, Winegar Bruce D
doaj +1 more source
Neural Regeneration Research, 2016 Isoflurane is a widely used inhaled anesthetic in the clinical setting. However, the mechanism underlying its effect on consciousness is under discussion.
Yi-qing Yin +5 more
doaj +1 more source
Scientific Reports, 2015 Pentameric ligand-gated ion channels (pLGICs) are targets of general anesthetics, but molecular mechanisms underlying anesthetic action remain debatable.
Qiang Chen +6 more
semanticscholar +1 more source
Inhalation anesthesia with isoflurane in a black jaguar (Panthera onca) for surgical repair of a fractured mandible [PDF]
, 2007 A black jaguar (Panthera onca) was anesthetized with a combination of medetomidine, ketamine and isoflurane in oxygen for radiological examination and surgical repair of a fractured mandible.
Bosmans, Tim +4 more
core
Long-term vascular access ports as a means of sedative administration in a rodent fMRI survival model [PDF]
, 2011 The purpose of this study is to develop a rodent functional magnetic resonance imaging (fMRI) survival model with the use of heparin-coated vascular access devices.
Cho, Younghoon R +7 more
core +2 more sources
Frontiers in Cellular Neuroscience, 2014 Commonly used anesthetic isoflurane has been reported to promote Alzheimer’s disease (AD) neuropathogenesis by inducing caspase-3 activation. However, the up-stream mechanisms of the isoflurane’s effects remain largely to be determined.
Yiying eZhang +9 more
doaj +1 more source
Origins of choice-related activity in mouse somatosensory cortex. [PDF]
, 2015 During perceptual decisions about faint or ambiguous sensory stimuli, even identical stimuli can produce different choices. Spike trains from sensory cortex neurons can predict trial-to-trial variability in choice.
Kwon, Sung E +3 more
core +2 more sources