Results 131 to 140 of about 221,447 (295)

Isoflurane Causes Only Minimal Increases in Coronary Blood Flow Independent of Oxygen Demand [PDF]

, 1991
Dermot Kenny, Lester T. Proctor, William T. Schmellng, John P. Kampine, David C. Warltier   +4 more
openalex   +1 more source

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

Advanced Materials, EarlyView.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade, Ashna A. Kumar, Samuel O. Nitschke, Paul Joyce, Elahe Minaei, Stephanie E. Reuter Lange, Chelsea Penney, Holly Warren, Ruby Shepherd, Jeremy N. Dinoro, Gordon G. Wallace, Anthony Dosseto, Sameera Ansar, Naila Islam, Alistair Lochhead, George Sharbeen, Phoebe A. Phillips, Morteza Aghmesheh, Wayne J. Hawthorne, Kara L. Vine‐Perrow   +19 more
wiley   +1 more source

Phenylephrine Increases Regional Cerebral Blood Flow Following Hemorrhage during Isoflurane–Oxygen Anesthesia [PDF]

, 1989
W. Alan C. Mutch, Louise A. Mato, K. R. A. Ringaert   +2 more
openalex   +1 more source

Study of a Novel Bi‐Layered Thermoplastic Polyurethane Patch for Congenital Diaphragmatic Hernia

Advanced Materials Interfaces, EarlyView.
Large congenital diaphragmatic hernia remains a challenge due to the poor compatibility of current prostheses. To tackle this problem, a bilayer thermoplastic polyurethane patch with tunable mechanical properties is engineered, whose fibrous side supports rapid fibroblast and myoblast colonization, while the smooth film limits adhesions.
Guillaume Leks, Julie Favre, Manon Zislin, Rodolphe Migneret, Jordana Hirtzel, Vincent Ball, Cendrine Seguin, Anne Hebraud, Emeline Lobry, Guy Schlatter, Nadia Bahlouli, Hamdi Jmal, Benoît Frisch, Sylvie Fournel, Isabelle Talon   +14 more
wiley   +1 more source

DIFFERENTIAL EFFECTS OF HALOTHANE, ENFLURANE AND ISOFLURANE ON TRANSIENTS AND PAPILLARY MUSCLE TENSION IN THE GUINEA PIG [PDF]

, 1988
Z J Bosnjak, A Aggarwal, LA Turner, John P. Kampine   +3 more
openalex   +1 more source

Radiotherapy Enhancement by Gold Nanocluster‐functionalized Nanoliposomes Using Polychromatic Orthovoltage X‐ray Irradiation

Advanced Materials Interfaces, EarlyView.
Lipid drug carriers to which ultra‐small gold nanoparticles were added enabled more efficient radiotherapy of cultured pancreatic cancer tumors. These nanoparticles boosted radiation‐induced damage to tumors by generating more reactive molecules, though higher gold levels are needed for strong benefits.
Nazareth Milagros Carigga Gutierrez, Eaazhisai Kandiah, Sofia Leo, Erwan Dupont, Fabrizio Johnson‐Corrales, Marc‐André Hograindleur, Sarvenaz Keshmiri, Hélène Elleaume, Benoit Busser, Romain Haudecoeur, Véronique Jacob, Anthony Vella, Véronique Josserand, Maxime Henry, Jean‐Luc Coll, Amandine Hurbin, Xavier Le Guével, Mans Broekgaarden   +17 more
wiley   +1 more source

Resveratrol protects against isoflurane-induced testicular injury: a stereological and molecular study in mice. [PDF]

Clinics (Sao Paulo)
Mohammadi Z, Alaee S, Abadi MK, Karami-Mohajeri S, Khodabandeh Z, Shokri S, Dutta S, Sengupta P, Kamyab H.   +8 more
europepmc   +1 more source

Perfusion Bioreactor Culture Incorporating Mechanical Confinement Enhances Mesenchymal Stem Cell Extracellular Vesicle Production and Wound Healing Potential

Advanced Materials Technologies, EarlyView.
Scalable manufacturing challenges and limited potency remain two of the most intransigent issues limiting clinical translation of EV therapeutics. Mechanical cues can induce phenotypic changes and increased vesiculation in EV source cells without the use of extraneous reagents, chemicals, and/or cargo, thereby potentially drastically improving the ...
Emily H. Powsner, Raith Nowak, Stephanie M. Kronstadt, Nicholas H. Pirolli, Talia J. Solomon, Kristin Nikolov, William Pieper Holeman, Ian M. Smith, Kimberly M. Stroka, John P. Fisher, Steven M. Jay   +10 more
wiley   +1 more source

CO and N₂ are not humane alternatives to CO₂ euthanasia in rats. [PDF]

Pflugers Arch
Calvet C, Villiger P, Prisco F, Buchholz T, Gantenbein F, Thöne-Reineke C, Gourévitch B, Wagner CA, Seebeck P.   +8 more
europepmc   +1 more source

IMMOBILIZATION OF CALIFORNIA SEA LIONS USING MEDETOMIDINE PLUS KETAMINE WITH AND WITHOUT ISOFLURANE AND REVERSAL WITH ATIPAMEZOLE [PDF]

, 2000
Martin Haulena, Frances M. D. Gulland, Donald G. Calkins, Terry R. Spraker   +3 more
openalex   +1 more source