Results 11 to 20 of about 280,533 (361)
Biomedicines, 2022 The therapeutic effects of volatile anesthetics on mental diseases, particularly schizophrenia, have gained considerable interest. Although isoflurane is a commonly used volatile anesthetic, there’s no more evidence that it could work on treating ...
Hualing Peng +3 more
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Isoflurane preconditioning confers cardioprotection by activation of ALDH2. [PDF]
PLoS ONE, 2013 The volatile anesthetic, isoflurane, protects the heart from ischemia/reperfusion (I/R) injury. Aldehyde dehydrogenase 2 (ALDH2) is thought to be an endogenous mechanism against ischemia-reperfusion injury possibly through detoxification of toxic ...
Xiao-E Lang +5 more
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Isoflurane preconditioning inhibited isoflurane-induced neurotoxicity [PDF]
Neuroscience Letters, 2007 The commonly used inhaled anesthetic isoflurane has been shown to be both neuroprotective and neurotoxic in various cell cultures and animal models. We hypothesize that, like cerebral ischemia, isoflurane is inherently neurotoxic. Limited exposure of isoflurane provides neuroprotection via induction of endogenous neuroprotective mechanisms ...
Huafeng Wei +3 more
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Frontiers in Pharmacology, 2022 Background: Electroencephalography (EEG) recordings under propofol exhibit an increase in slow and alpha oscillation power and dose-dependent phase–amplitude coupling (PAC), which underlie GABAA potentiation and the central role of thalamocortical ...
Jingyao Jiang +12 more
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Scientific Reports, 2022 Endoplasmic reticulum (ER) stress has been linked to anesthesia-induced neurotoxicity, but melatonin seems to play a protective role against ER stress.
Hyun-Jung Shin +5 more
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Isoflurane and Carbon Dioxide Elicit Similar Behavioral Responses in Rats
Animals, 2020 Euthanasia in rodents is an ongoing topic of debate due to concerns regarding the aversive nature of gases with anesthetic properties such as carbon dioxide (CO2) and isoflurane.
Satyajit Kulkarni, Debra Hickman
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Isoflurane on brain inflammation [PDF]
Neurobiology of Disease, 2014 Brain inflammation may play an important role in the pathophysiology of early brain injury after subarachnoid hemorrhage (SAH). Our aim was to demonstrate brain inflammation development and to determine whether isoflurane, a clinically available volatile anesthetic agent, prevents brain inflammation after SAH.
Yu Hasegawa +5 more
openaire +4 more sources
The cerebrovascular effects of adrenaline, noradrenaline and dopamine infusions under propofol and isoflurane anaesthesia in sheep [PDF]
, 2002 Publisher's copy made available with the permission of the publisher © Australian Society of AnaesthetistsInfusions of catecholamines are frequently administered to patients receiving propofol or isoflurane anaesthesia.
Fortin D. +5 more
core +2 more sources
Cellular Physiology and Biochemistry, 2013 Background: Survival of random-pattern skin flaps is important for the success of plastic and reconstructive surgeries. This study investigates isoflurane-induced protection against ischemia of skin flap and the underlying molecular mechanism in this ...
Yu Sun +4 more
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Diagnostic Pathology, 2020 Background Isoflurane can lead to neuron damage to the developing brain, resulting in learning and memory disability. The aim of this study was to investigate the role of miR-142-5p on isoflurane-induced neurological impairment.
Cuili Xie +3 more
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