Results 11 to 20 of about 263,583 (339)
Objective: Surgery is the first line treatment of colorectal cancer (CRC). Anesthetic isoflurane may improve outcomes of cancer surgery. Herein, we investigated the effects of isoflurane on malignant behaviors of CRC cells and its underlying therapeutic ...
Zhe Cai, Liangyuan Suo, Zeqing Huang
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Paired assessment of volatile anesthetic concentrations with synaptic actions recorded in vitro. [PDF]
The volatile anesthetic isoflurane poses a number of experimental challenges in the laboratory. Due to its rapid evaporation, the open conditions of most in vitro electrophysiological recording systems make the determination of actual isoflurane ...
Stuart J McDougall+5 more
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Ferroptosis contributes to isoflurane-induced neurotoxicity and learning and memory impairment
Ferroptosis is a novel type of programmed cell death, which is different from apoptosis and autophagic cell death. Recently, ferroptosis has been indicated to contribute to the in vitro neurotoxicity induced by isoflurane, which is one of the most common
Pengfei Liu+5 more
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SummaryA comparison of the analgesic efficacy of Entonox (50% nitrous oxide in oxygen) and Entonox with 0.2% isofturane was made in 18 consenting mothers during the first stage of labour. The inhalational gases were self‐administered during contractions over a 3 h study period using a standard Entonox demand valve and breathing system.
M. A. Hasan, T. A. Thomas, M. Y. K. Wee
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Isoflurane for conscious sedation [PDF]
SummaryIsoflurane 0.5% in oxygen for conscious sedation was compared with placebo (oxygen) and with an equipotent concentration of nitrous oxide in oxygen, in patients scheduled for surgical removal of bilateral, similarly impacted lower third molars. The majority of patients were sedated with 0.5% isoflurane in oxygen and preferred it to both placebo ...
J. B. Rosenquist, M. R. C. Rodrigo
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Postanesthetic effects of isoflurane on behavioral phenotypes of adult male C57BL/6J mice. [PDF]
Isoflurane was previously the major clinical anesthetic agent but is now mainly used for veterinary anesthesia. Studies have reported widespread sites of action of isoflurane, suggesting a wide array of side effects besides sedation. In the present study,
Kumiko Yonezaki+6 more
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The therapeutic effects of volatile anesthetics on mental diseases, particularly schizophrenia, have gained considerable interest. Although isoflurane is a commonly used volatile anesthetic, there’s no more evidence that it could work on treating ...
Hualing Peng+3 more
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Isoflurane preconditioning confers cardioprotection by activation of ALDH2. [PDF]
The volatile anesthetic, isoflurane, protects the heart from ischemia/reperfusion (I/R) injury. Aldehyde dehydrogenase 2 (ALDH2) is thought to be an endogenous mechanism against ischemia-reperfusion injury possibly through detoxification of toxic ...
Xiao-E Lang+5 more
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Endoplasmic reticulum (ER) stress has been linked to anesthesia-induced neurotoxicity, but melatonin seems to play a protective role against ER stress.
Hyun-Jung Shin+5 more
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Increased Respiratory Drive after Prolonged Isoflurane Sedation : A Retrospective Cohort Study [PDF]
Low-dose isoflurane stimulates spontaneous breathing. We, therefore, tested the hypothesis that isoflurane compared to propofol sedation for at least 48 h is associated with increased respiratory drive in intensive care patients after sedation stop ...
Albrecht, Frederic Walter+5 more
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