Results 11 to 20 of about 263,583 (339)

Isoflurane Suppresses Proliferation, Migration, and Invasion and Facilitates Apoptosis in Colorectal Cancer Cells Through Targeting miR-216

open access: yesFrontiers in Medicine, 2021
Objective: Surgery is the first line treatment of colorectal cancer (CRC). Anesthetic isoflurane may improve outcomes of cancer surgery. Herein, we investigated the effects of isoflurane on malignant behaviors of CRC cells and its underlying therapeutic ...
Zhe Cai, Liangyuan Suo, Zeqing Huang
doaj   +1 more source

Paired assessment of volatile anesthetic concentrations with synaptic actions recorded in vitro. [PDF]

open access: yesPLoS ONE, 2008
The volatile anesthetic isoflurane poses a number of experimental challenges in the laboratory. Due to its rapid evaporation, the open conditions of most in vitro electrophysiological recording systems make the determination of actual isoflurane ...
Stuart J McDougall   +5 more
doaj   +1 more source

Ferroptosis contributes to isoflurane-induced neurotoxicity and learning and memory impairment

open access: yesCell Death Discovery, 2021
Ferroptosis is a novel type of programmed cell death, which is different from apoptosis and autophagic cell death. Recently, ferroptosis has been indicated to contribute to the in vitro neurotoxicity induced by isoflurane, which is one of the most common
Pengfei Liu   +5 more
doaj   +1 more source

Isoflurane in labour [PDF]

open access: yesAnaesthesia, 1993
SummaryA comparison of the analgesic efficacy of Entonox (50% nitrous oxide in oxygen) and Entonox with 0.2% isofturane was made in 18 consenting mothers during the first stage of labour. The inhalational gases were self‐administered during contractions over a 3 h study period using a standard Entonox demand valve and breathing system.
M. A. Hasan, T. A. Thomas, M. Y. K. Wee
openaire   +3 more sources

Isoflurane for conscious sedation [PDF]

open access: yesAnaesthesia, 1988
SummaryIsoflurane 0.5% in oxygen for conscious sedation was compared with placebo (oxygen) and with an equipotent concentration of nitrous oxide in oxygen, in patients scheduled for surgical removal of bilateral, similarly impacted lower third molars. The majority of patients were sedated with 0.5% isoflurane in oxygen and preferred it to both placebo ...
J. B. Rosenquist, M. R. C. Rodrigo
openaire   +7 more sources

Postanesthetic effects of isoflurane on behavioral phenotypes of adult male C57BL/6J mice. [PDF]

open access: yesPLoS ONE, 2015
Isoflurane was previously the major clinical anesthetic agent but is now mainly used for veterinary anesthesia. Studies have reported widespread sites of action of isoflurane, suggesting a wide array of side effects besides sedation. In the present study,
Kumiko Yonezaki   +6 more
doaj   +1 more source

Isoflurane Rescue Schizophrenia-Related Deficits through Parvalbumin-Positive Neurons in the Dentate Gyrus

open access: yesBiomedicines, 2022
The therapeutic effects of volatile anesthetics on mental diseases, particularly schizophrenia, have gained considerable interest. Although isoflurane is a commonly used volatile anesthetic, there’s no more evidence that it could work on treating ...
Hualing Peng   +3 more
doaj   +1 more source

Isoflurane preconditioning confers cardioprotection by activation of ALDH2. [PDF]

open access: yesPLoS ONE, 2013
The volatile anesthetic, isoflurane, protects the heart from ischemia/reperfusion (I/R) injury. Aldehyde dehydrogenase 2 (ALDH2) is thought to be an endogenous mechanism against ischemia-reperfusion injury possibly through detoxification of toxic ...
Xiao-E Lang   +5 more
doaj   +1 more source

Melatonin reduces the endoplasmic reticulum stress and polyubiquitinated protein accumulation induced by repeated anesthesia exposure in Caenorhabditis elegans

open access: yesScientific Reports, 2022
Endoplasmic reticulum (ER) stress has been linked to anesthesia-induced neurotoxicity, but melatonin seems to play a protective role against ER stress.
Hyun-Jung Shin   +5 more
doaj   +1 more source

Increased Respiratory Drive after Prolonged Isoflurane Sedation : A Retrospective Cohort Study [PDF]

open access: yes, 2022
Low-dose isoflurane stimulates spontaneous breathing. We, therefore, tested the hypothesis that isoflurane compared to propofol sedation for at least 48 h is associated with increased respiratory drive in intensive care patients after sedation stop ...
Albrecht, Frederic Walter   +5 more
core   +1 more source

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