Results 21 to 30 of about 221,447 (295)

The effect of four anaesthetic protocols for maintenance of anaesthesia on trans-diaphragmatic pressure in dogs. [PDF]

open access: yesPLoS ONE, 2013
The diaphragm is the main inspiratory muscle and the main indicator of diaphragmatic contractility is the trans-diaphragmatic pressure (Pdi). The aim of this clinical study was to determine the effect of four different anaesthetic protocols on Pdi in ...
Kiriaki Pavlidou   +4 more
doaj   +1 more source

Isoflurane postconditioning reduces ischemia-induced nuclear factor-κB activation and interleukin 1β production to provide neuroprotection in rats and mice

open access: yesNeurobiology of Disease, 2013
Application of isoflurane, a volatile anesthetic, after brain ischemia can reduce ischemic brain injury in rodents (isoflurane postconditioning). This study is designed to determine whether isoflurane postconditioning improves long-term neurological ...
Hong Li   +5 more
doaj   +1 more source

Comparison of the effects of two anesthetics, isoflurane and urethane, on bladder function in rats

open access: yesJournal of Pharmacological Sciences, 2023
We compared the effects of two anesthetics, isoflurane and urethane on bladder function in rats. Arterial pressure, cystometry (CMG), and rhythmic bladder contractions (RBCs) under isovolumetric conditions, mechanosensitive single-unit afferent ...
Naoki Aizawa, Tomoe Fujita
doaj   +1 more source

The volatile anesthetic isoflurane increases endothelial adenosine generation via microparticle ecto-5'-nucleotidase (CD73) release.

open access: yesPLoS ONE, 2014
Endothelial dysfunction is common in acute and chronic organ injury. Isoflurane is a widely used halogenated volatile anesthetic during the perioperative period and protects against endothelial cell death and inflammation.
Mihwa Kim   +4 more
doaj   +1 more source

Isoflurane impairs oogenesis through germ cell apoptosis in C. elegans

open access: yesScientific Reports, 2021
Anesthetic isoflurane has been reported to induce toxicity. However, the effects of isoflurane on fecundity remain largely unknown. We established a system in C. elegans to investigate the effects of isoflurane on oogenesis.
Tao Zhang   +8 more
doaj   +1 more source

Minocycline attenuates cognitive impairment induced by isoflurane anesthesia in aged rats. [PDF]

open access: yesPLoS ONE, 2013
Postoperative cognitive dysfunction (POCD) is a clinical phenomenon characterized by cognitive deficits in patients after anesthesia and surgery, especially in geriatric surgical patients. Although it has been documented that isoflurane exposure impaired
Feijuan Kong   +6 more
doaj   +1 more source

Janus Kinase Mediates Faster Recovery From Sevoflurane Anesthesia Than Isoflurane Anesthesia in the Migratory Locusts

open access: yesFrontiers in Physiology, 2022
Inhalation anesthetics isoflurane and sevoflurane have been widely used in clinical practice for anesthesia. However, the molecular mechanisms underlying the faster recovery from sevoflurane anesthesia than isoflurane anesthesia remain largely ...
Zongyuan Ma   +4 more
doaj   +1 more source

Isoflurane anesthesia promotes cognitive impairment by inducing expression of β-amyloid protein-related factors in the hippocampus of aged rats. [PDF]

open access: yesPLoS ONE, 2017
Isoflurane anesthesia has been shown to be responsible for cognitive impairment in Alzheimer's disease (AD) and development of AD in the older age groups.
Shuai Zhang   +6 more
doaj   +1 more source

Intraoperative administration of isoflurane improves survival in rats exposed to caecal ligation and puncture

open access: yesBJA Open, 2022
Background: Emerging data suggest that volatile anaesthetic agents may be protective during critical illness. Methods: Three-month-old Sprague Dawley rats were randomly allocated to one of four groups: isoflurane during surgery followed by 3 days of ...
Keita Ikeda   +2 more
doaj   +1 more source

Sleep Deprivation Aggravates Cognitive Impairment by the Alteration of Hippocampal Neuronal Activity and the Density of Dendritic Spine in Isoflurane-Exposed Mice

open access: yesFrontiers in Behavioral Neuroscience, 2020
Isoflurane contributes to cognitive deficits when used as a general anesthetic, and so does sleep deprivation (SD). Patients usually suffer from insomnia before an operation due to anxiety, fear, and other factors. It remains unclear whether preoperative
Kai Zhang   +13 more
doaj   +1 more source

Home - About - Disclaimer - Privacy