Results 21 to 30 of about 263,583 (339)

Isoflurane preconditioning inhibited isoflurane-induced neurotoxicity [PDF]

open access: yesNeuroscience Letters, 2007
The commonly used inhaled anesthetic isoflurane has been shown to be both neuroprotective and neurotoxic in various cell cultures and animal models. We hypothesize that, like cerebral ischemia, isoflurane is inherently neurotoxic. Limited exposure of isoflurane provides neuroprotection via induction of endogenous neuroprotective mechanisms ...
Huafeng Wei   +3 more
openaire   +3 more sources

Isoflurane – Evaluation of a BAT value [PDF]

open access: yes, 2023
The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area re-evaluated isoflurane [26675-46-7] and a maximum concentration at the workplace (MAK value) of 2 ml/m3 has been set for isoflurane.
Arand, Michael   +4 more
core   +1 more source

Isoflurane on brain inflammation [PDF]

open access: yesNeurobiology of Disease, 2014
Brain inflammation may play an important role in the pathophysiology of early brain injury after subarachnoid hemorrhage (SAH). Our aim was to demonstrate brain inflammation development and to determine whether isoflurane, a clinically available volatile anesthetic agent, prevents brain inflammation after SAH.
Yu Hasegawa   +5 more
openaire   +4 more sources

Signatures of Thalamocortical Alpha Oscillations and Synchronization With Increased Anesthetic Depths Under Isoflurane

open access: yesFrontiers in Pharmacology, 2022
Background: Electroencephalography (EEG) recordings under propofol exhibit an increase in slow and alpha oscillation power and dose-dependent phase–amplitude coupling (PAC), which underlie GABAA potentiation and the central role of thalamocortical ...
Jingyao Jiang   +12 more
doaj   +1 more source

The cerebrovascular effects of adrenaline, noradrenaline and dopamine infusions under propofol and isoflurane anaesthesia in sheep [PDF]

open access: yes, 2002
Publisher's copy made available with the permission of the publisher © Australian Society of AnaesthetistsInfusions of catecholamines are frequently administered to patients receiving propofol or isoflurane anaesthesia.
Fortin D.   +5 more
core   +2 more sources

Isoflurane Preconditioning Increases Survival of Rat Skin Random-Pattern Flaps by Induction of HIF-1α Expression

open access: yesCellular Physiology and Biochemistry, 2013
Background: Survival of random-pattern skin flaps is important for the success of plastic and reconstructive surgeries. This study investigates isoflurane-induced protection against ischemia of skin flap and the underlying molecular mechanism in this ...
Yu Sun   +4 more
doaj   +1 more source

Neuroprotective effects of miR-142-5p downregulation against isoflurane-induced neurological impairment

open access: yesDiagnostic Pathology, 2020
Background Isoflurane can lead to neuron damage to the developing brain, resulting in learning and memory disability. The aim of this study was to investigate the role of miR-142-5p on isoflurane-induced neurological impairment.
Cuili Xie   +3 more
doaj   +1 more source

The effect of four anaesthetic protocols for maintenance of anaesthesia on trans-diaphragmatic pressure in dogs. [PDF]

open access: yesPLoS ONE, 2013
The diaphragm is the main inspiratory muscle and the main indicator of diaphragmatic contractility is the trans-diaphragmatic pressure (Pdi). The aim of this clinical study was to determine the effect of four different anaesthetic protocols on Pdi in ...
Kiriaki Pavlidou   +4 more
doaj   +1 more source

Anesthesia triggers drug delivery to experimental glioma in mice by hijacking caveolar transport [PDF]

open access: yes, 2021
Background: Pharmaceutical intervention in the CNS is hampered by the shielding function of the blood-brain barrier (BBB). To induce clinical anesthesia, general anesthetics such as isoflurane readily penetrate the BBB.
Berghoff, S.   +23 more
core   +5 more sources

Electroencephalogram of Healthy Horses During Inhaled Anesthesia. [PDF]

open access: yes, 2015
BackgroundPrevious study of the diagnostic validity of electroencephalography (EEG) to detect abnormalities in equine cerebral cortical function relied on the administration of various drugs for sedation, induction, and maintenance of general anesthesia ...
Aleman, MR   +8 more
core   +1 more source

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