Results 101 to 110 of about 53,308 (359)

A Multi-Moded RF Delay Line Distribution System for the Next Linear Collider

, 2002
The Delay Line Distribution System (DLDS) is an alternative to conventional pulse compression, which enhances the peak power of rf sources while matching the long pulse of those sources to the shorter filling time of accelerator structures. We present an
Kroll, N., Li, Z., Miller, R., Nantista, C., Neilson, J., Ruth, R., Tantawi, S. G., Wilson, P.   +7 more
core   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Modular, Multiport AC-DC Converter with Add-On HF Isolating Units

Energies
In this paper, we propose a novel concept of a modular, multiport, single-stage, bidirectional, isolated, three-phase AC-DC converter system. This new system is realized using add-ons to a standard voltage source inverter, including both grid-connected ...
Pawel B. Derkacz, Pawel Milewski, Daniel Wojciechowski, Natalia Strzelecka, Ryszard Strzelecki   +4 more
doaj   +1 more source

Polynomial Curve Slope Compensation for Peak-Current-Mode-Controlled Power Converters [PDF]

, 2019
Linear ramp slope compensation (LRC) and quadratic slope compensation (QSC) are commonly implemented in peak-current-mode-controlled dc-dc converters in order to minimize subharmonic and chaotic oscillations.
Deng, Xu, Giaouris, Damian, He, Xiangning, Li, Wuhua, Pickert, Volker, Wu, Haimeng   +5 more
core   +2 more sources

Non-Isolated Fourth-Order Boost DC-DC Converter for Power Management in Low Voltage Low Power DC Grids: Design and Interaction Analysis [PDF]

, 2020
Ashima Kulshreshtha, Anmol Ratna Saxena, Mummadi Veerachary   +2 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Modeling the System for Hybrid Renewable Energy Using Highly Efficient Converters and Generator

CES Transactions on Electrical Machines and Systems
High-efficient isolated DC/DC converters with a high-efficiency synchronous reluctance generator (SRG) are the ultimate solutions in DC microgrid systems.
Tefera Kitaba
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Bidirectional DC-DC Converter Topologies for Hybrid Energy Storage Systems in Electric Vehicles: A Comprehensive Review

Energies
Electric Vehicles (EV) significantly contribute to reducing carbon emissions and promoting sustainable transportation. Among EV technologies, hybrid energy storage systems (HESS), which combine fuel cells, power batteries, and supercapacitors, have been ...
Yan Tong, Issam Salhi, Qin Wang, Gang Lu, Shengyu Wu   +4 more
doaj   +1 more source

Asymmetric snubberless current-fed full-bridge isolated DC-DC converters

Electrical, Control and Communication Engineering, 2018
This paper presents two isolated current-fed fullbridge DC-DC converters that can be used to interface a lower voltage source into a DC bus of higher voltage.
Kosenko Roman, Blinov Andrei, Vinnikov Dmitri, Chub Andrii   +3 more
doaj   +1 more source