Results 91 to 100 of about 2,587,577 (305)

Theory and simulations on strong pinning of vortex lines by nanoparticles

, 2011
The pinning of vortex lines by an array of nanoparticles embedded inside superconductors has become the most efficient practical way to achieve high critical currents.
Kolton, Alejandro B., Koshelev, Alexei E.   +1 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Isolation and Culture of Skin-Derived Differentiated and Stem-Like Cells Obtained from the Arabian Camel (Camelus dromedarius)

Animals, 2019
Elite camels often suffer from massive injuries. Thus, there is a pivotal need for a cheap and readily available regenerative medicine source. We isolated novel stem-like cells from camel skin and investigated their multipotency and resistance against ...
Islam M. Saadeldin, Ayman Abdel-Aziz Swelum, Ahmed E. Noreldin, Hammed A. Tukur, Aaser M. Abdelazim, Mosleh M. Abomughaid, Abdullah N. Alowaimer   +6 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Analysis of Electric Leakage Fault of Mine Multi-level Power Supply Network and Its Detectio

Gong-kuang zidonghua, 2012
The paper analyzed fault components at the electric leakage moment of isolated neutral power supply system and power supply network connected to earth through an arc suppression coil, and got electrical characteristics of fault point.
LV Liang-jun, JIANG Jin-feng, WANG Wen-ji   +2 more
doaj  

Herschel observations of EXtra-Ordinary Sources (HEXOS): Methanol as a probe of physical conditions in Orion KL [PDF]

, 2011
We have examined methanol emission from Orion KL withthe Herschel/HIFI instrument, and detected two methanol bands centered at 524 GHz and 1061 GHz. The 524 GHz methanol band (observed in HIFI band 1a) is dominated by the isolated ΔJ = 0, K = −4 → −3 ...
Bell, T. A., Blake, G. A., Latter, W. B., Lis, D. C., Lord, S. D., Morris, P., Phillips, T. G., Wang, S., Zmuidzinas, J.   +8 more
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

A Study in Blue: The Baryon Content of Isolated Low Mass Galaxies

, 2015
We study the baryon content of low mass galaxies selected from the Sloan Digital Sky Survey (SDSS DR8), focusing on galaxies in isolated environments where the complicating physics of galaxy-galaxy interactions are minimized. We measure neutral hydrogen (
Blanton, Michael R., Bradford, Jeremy D., Geha, Marla C.   +2 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

In vivo analgesic, anti-inflammatory, sedative, muscle relaxant activities, and docking studies of 3’,4’,7,8-tetrahydroxy-3-methoxyflavone isolated from Pistacia chinensis

Drug Target Insights
Background: Pistacia chinensis is extensively employed in traditional medicine. This study aimed to isolate and evaluate the therapeutic effects of 3’4’78-tetrahydroxy-3-methoxyflavone from P. chinensis crude extract.
Abdur Rauf, Umer Rashid, Zuneera Akram, Anees Saeed, Naveed Muhammad, Najla Al Masoud, Taghrid S. Alomar, Saima Naz, Marcello Iriti   +8 more
doaj   +1 more source