Results 111 to 120 of about 1,133,012 (313)
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Mitigation of the Electric Field Under EHVTL in Limited Space Crowded With Human Activities
IEEE AccessWorkers in the activities under high-voltage lines are exposed to the influence of the electric field of these lines, which may cause, in some cases, death as a result of some serious accidents such as the collapse of the towers and the occurrence of ...
Mohamed H. Elmashtoly +3 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Chemical Constituents From the Leaves of Gagn. and Their Cytotoxic Activity
Natural Product CommunicationsObjective: The ultimate objective of this study was to isolate bioactive compounds from Grewia bulot Gagn. leaves and evaluate their cytotoxicity against a panel of human cancer cell lines.
Ty Viet Pham +7 more
doaj +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Cytotoxic potential of S. levi total extract and isolated metabolites against cancer cell lines.
Cytotoxic potential of S. levi total extract and isolated metabolites against cancer cell lines.
Mamdouh Nabil Samy (8080397) +8 more
core +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Lines of principal curvature on canal surfaces in R³
Anais da Academia Brasileira de Ciências, 2006 In this paper are determined the principal curvatures and principal curvature lines on canal surfaces which are the envelopes of families of spheres with variable radius and centers moving along a closed regular curve in R³.
Garcia Ronaldo +2 more
doaj
Two Diarylundecanones Isolated from
Natural Product Communications, 2017 Ardisinones G-H ( 1–2 ), two new diarylundecanones, were isolated from the ethanol extract of aerial parts of Ardisia tenera Mez. Their structures were elucidated by interpretation of the spectroscopic evidence.
Chong-Yu Lu +7 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source