Results 201 to 210 of about 2,609,725 (348)

Signal transducer and activator of transcription 3 activation up-regulates interleukin-6 autocrine production: a biochemical and genetic study of established cancer cell lines and clinical isolated human cancer cells [PDF]

, 2010
Wei-Lun Huang, Hsuan-Heng Yeh, Chien‐Chung Lin, Wu‐Wei Lai, Jang-Yang Chang, Wen‐Tsan Chang, Wu‐Chou Su   +6 more
openalex   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Antiproliferative Effect of 24-Deoxysericoside From Terminalia macroptera Guill. & Perr. (Combretaceae) Against Breast Carcinoma: In Vitro, Molecular Docking and ADME Assessment. [PDF]

Cancer Rep (Hoboken)
Feunaing RT, Tamfu AN, Gbaweng AJY, Djoko CLT, Talla E, Anouar EH, Zingue S.   +6 more
europepmc   +1 more source

Immunopeptidomes isolated from 4 B-cell lines homozygous for HLA-C*06:02

Prinz, Jörg
openalex   +1 more source

Capilliposide Isolated from Lysimachia capillipes Hemsl. Induces ROS Generation, Cell Cycle Arrest, and Apoptosis in Human Nonsmall Cell Lung Cancer Cell Lines [PDF]

, 2014
Zhenghua Fei, Kan Wu, Yunliang Chen, Bing Wang, Shirong Zhang, Shenglin Ma   +5 more
openalex   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

PU.1 restores microglial dysfunction caused by C9ORF72 repeat expansions in neural organoids. [PDF]

Brain
Ljubikj T, Mars MZ, van der Geest AT, Jakobs CE, Bessler N, Donega V, van den Oetelaar XPRM, de Wit M, Pasterkamp RJ.   +8 more
europepmc   +1 more source

Reaction of maize inbred lines to the bacterium Pantoea ananas isolated from Phaeosphaeria leaf spot lesions

, 2002
Luzia Doretto Paccola-Meirelles, W. F. Meirelles, S. N. Parentoni, I. E. Marriel, A. S. Ferreira, C. R. Casela   +5 more
openalex   +1 more source

Initial characterization of drug resistant cancer stem cells isolated from primary brain tumors (astrocytoma) cell lines generated from Saudi patients [PDF]

, 2014
Ishaq Khan, Mohammed Bangash, Saleh Baeesa, Awatif Jamal, Hanadi Qashqari, Adel Abuzenadah, Mohammed Al‐Qahtani, Ghazi A. Damanhouri, Hans-Juergen Schulten, Deema Hussein, Adeel Chaudhary   +10 more
openalex   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source