Results 211 to 220 of about 2,609,725 (348)

<i>Bessera elegans</i> (Asparagaceae): Botany, Phytochemistry, and Cytotoxic and Insecticidal Activities of an Underexplored Mexican Species. [PDF]

Molecules
Tagle-Emigdio LJ, Salinas-Sánchez DO, Toledo-Hernández E, Mendoza-Catalán MA, Zacapala-Gómez AE, Hernández-Sotelo D, Leyva-Bello AG, Delgado-Nuñez EJ, Figueroa-Brito R, Sotelo-Leyva C.   +9 more
europepmc   +1 more source

Generation, establishment and characterization of three pluripotent stem cell lines (CVTTHi002-A, CVTTHi003-A and CVTTHi004-A) from primary testicular somatic cells isolated from two prepuberal and one peripuberal Klinefelter Syndrome (47 XXY) patients

Myriam Martin‐Inaraja, Irene Romayor, A.A. Câmara, Lara Herrera, Ainhoa Palacios, Maria Villaverde, Silvia J. Santos, Miguel Ángel Vesga, Beatriz Barreña, Ana M. Aransay, Juan Anguíta, Estíbaliz Solorzano, María Begoña Prieto, Roberto Matorras, Cristina Eguizábal   +14 more
openalex   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Surface Plasmon Resonance as a Potential Diagnostic Tool for the Detection of CXC Chemokine Receptor 4 (CXCR4) on Extracellular Vesicles. [PDF]

Biosensors (Basel)
Verleye K, Noppen S, Boonen A, Yildizhan Y, Van Loy T, Heens C, Vanderhoydonc F, Pinheiro C, Lins PMP, Bronckaers A, Hendrix A, Swinnen JV, Spasic D, Lammertyn J, Pannecouque C, Schols D.   +15 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Optimized methods for obtaining sequencing-quality RNA from blubber of free-ranging cetaceans collected under field conditions. [PDF]

Conserv Physiol
Boateng KKA, Allen RF, Wells RS, Kellar NM, Khudyakov JI.   +4 more
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Organic Electrochemical Transistors for Real-Time Detection of Immune System Early Activation during Atezolizumab-Bevacizumab Treatment in Hepatocellular Carcinoma. [PDF]

ACS Appl Mater Interfaces
Decataldo F, Arleo A, Montagner A, Cortelli G, Cioroianu CS, Piscaglia F, Fraboni B, Gramantieri L, Giovannini C.   +8 more
europepmc   +1 more source

CONTACT-INHIBITED REVERTANT CELL LINES ISOLATED FROM SV40-TRANSFORMED CELLS [PDF]

, 1973
N. Scott McNutt, Lloyd A. Culp, Paul H. Black   +2 more
openalex   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source