Results 241 to 250 of about 1,133,012 (313)

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Anticancer Potential of Piericidin A1 and Derivatives Isolated From Streptomyces sp. Associated With Palythoa variabilis From Brazilian Reefs. [PDF]

Chem Biodivers
Sahm BDB, Florêncio KGD, Pinto FCL, Maia AIV, Rocha CAM, Jimenez PC, Pessoa ODL, Lotufo TMC, Costa-Lotufo LV, Wilke DV.   +9 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Transgenic expression of human signal regulatory protein alpha (SIRPα) in BALB/c Rag2^null/Jak3^null immunodeficient mice enhances human lymphoma xenografts by reducing phagocytosis. [PDF]

Transgenic Res
Panaampon J, Ogawa T, Shiota A, Okada S.
europepmc   +1 more source

Back to the future 2: the implications of germplasm structure on the balance between short- and long-term genetic gain in a changing target population of environments. [PDF]

G3 (Bethesda)
Technow F, Podlich D, Cooper M.
europepmc   +1 more source

FOXM1-Specific TCR-Engineered T Cells Target Non-Small Cell Lung Cancer. [PDF]

Cancer Immunol Res
Bontekoe E, Zhang M, Jiang P, Montoya A, Shulga Y, Slone JK, Paul E, Polera C, Forward S, Nassif Rausseo B, Assita ER, Xing C, Molkentine DP, Morris BB, Polic I, Roszik J, Salgado R, Vaishnavi A, Deniger D, Tran HT, Gibbons DL, Vaporciyan A, Gillison ML, Wistuba II, Kavraki LE, Zhang J, Lizee G, Yee C, Hwu P, Kwok S, Jaeger AM, Heymach JV, Reuben A.   +32 more
europepmc   +1 more source

The inositol pyrophosphate 5-InsP₇ regulates mitochondrial polyphosphate synthesis and bioenergetic function. [PDF]

J Biol Chem
Ladke JS, Khan A, Singh A, Jessen HJ, Kolthur-Seetharam U, Jaiswal M, Bhandari R.   +6 more
europepmc   +1 more source

ROMO1 and mitochondrial complex II/SDH are required for spare respiratory capacity and glucose homeostasis in mice. [PDF]

Diabetologia
Wells L, Yang Q, Iorio C, Peragerasingam M, Campbell Z, Ng AC, Reeks C, Yee SP, Screaton RA.   +8 more
europepmc   +1 more source

Novel Selective Anticancer Effect of Epididymis-Derived Extracellular Vesicles Against HCC38 and MCF-7 Breast Cancer Cell Lines. [PDF]

Int J Mol Sci
Zoabi R, Ali Saleh Z, Issaq E, Morad E, Miari R, Taha H, Kadriya A, Samson AO, Falah M.   +8 more
europepmc   +1 more source