Results 61 to 70 of about 4,498,123 (349)

One Child\u27s Story of School-experienced Isolation and Rejection [PDF]

open access: yes, 2016
For twelve years of school, a tiny girl endured isolation and rejection from her peers most likely due to a physical abnormality. As the girl remembers, the educators in a small, rural school district did little to support her as she was ostracized by ...
Gresham, Gloria J, Dr.
core   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Ageing in place and social isolation in rural dwelling older adults : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Health Psychology at Massey University, Manawatu, New Zealand [PDF]

open access: yes, 2016
This research set out to answer three related research questions. Firstly, if and how rural dwelling older adults experience social isolation; secondly, what aspects of community were seen as contributing to or buffering against social isolation; and ...
Lilburn, Lucy Elizabeth Rose
core  

Protein processing characterized by a gel-free proteomics approach [PDF]

open access: yes, 2008
We describe a method for the specific isolation of representative N-terminal peptides of proteins and their proteolytic fragments. Their isolation is based on a gel-free, peptidecentric proteomics approach using the principle of diagonal chromatography ...
A. Staes   +17 more
core   +1 more source

Thermal Evolution near Heat-Generating Nuclear Waste Canisters Disposed in Horizontal Drillholes

open access: yesEnergies, 2019
We consider the disposal of spent nuclear fuel and high-level radioactive waste in horizontal holes drilled into deep, low-permeable geologic formations using directional drilling technology.
Stefan Finsterle   +4 more
doaj   +1 more source

Isolation is not the answer [PDF]

open access: yesNature, 2004
International scientific collaboration is the best defence against bioterror.
openaire   +3 more sources

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

Electrical Resistivity Structure and Helium Isotopes around Naruko Volcano, Northeastern Japan and Its Implication for the Distribution of Crustal Magma

open access: yesInternational Journal of Geophysics, 2010
The two-dimensional electrical resistivity structure beneath Naruko volcano was determined using magnetotelluric soundings. The resulting model shows that a prominent conductor exists through the middle crust to the uppermost mantle beneath the volcano ...
Koichi Asamori   +3 more
doaj   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

open access: yesFEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche   +2 more
wiley   +1 more source

3-Difluoromethyl-5-[4-(trifluoromethyl)phenyl]isoxazole

open access: yesIUCrData, 2018
The title molecule, C11H6F5NO, lies on a mirror plane in the orthorhombic unit cell, with only two F atoms each of the difluoro and trifluoromethyl substituents lying out of the plane.
Hui Zhao
doaj   +1 more source

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