Results 111 to 120 of about 333,047 (329)

Variability in contact precautions to control the nosocomial spread of multi-drug resistant organisms in the endemic setting: a multinational cross-sectional survey

open access: yesAntimicrobial Resistance and Infection Control, 2018
Background Definitions and practices regarding use of contact precautions and isolation to prevent the spread of gram-positive and gram-negative multidrug-resistant organisms (MDRO) are not uniform.
Danielle Vuichard Gysin   +5 more
doaj   +1 more source

Imitation of Life: Advanced system for native Artificial Evolution [PDF]

open access: yesarXiv, 2011
A model for artificial evolution in native x86 Windows systems has been developed at the end of 2010. In this text, further improvements and additional analogies to natural microbiologic processes are presented. Several experiments indicate the capability of the system - and raise the question of possible countermeasures.
arxiv  

Confinement by Liquid‐Liquid Interface Replicates In Vivo Neutrophil Deformations and Elicits Bleb‐Based Migration

open access: yesAdvanced Science, EarlyView.
Leukocytes sense mechanical cues provided by surrounding cells to regulate motility. Replicating the confining pressures applied by soft, elastic tissues in vitro is challenging. Here, the use of liquid‐liquid interfaces is introduced to model forces exerted by surrounding cells. Confining pressures are tunable by controlling interfacial curvature, and
Jonathan H. Schrope   +13 more
wiley   +1 more source

Native-PAGE analysis of protein aggregation upon viral infection in mouse macrophages

open access: yesSTAR Protocols, 2022
Summary: Upon viral infection, several proteins in the innate signaling pathway form aggregates, which in turn promote the activation of innate antiviral immune response.
Zhenzhen Yan, Hansen Liu, Chengjiang Gao
doaj  

Thermodynamic properties of microbian populations on biological membranes [PDF]

open access: yesarXiv, 2013
In this work we to develop a general statistical mechanic formalism to study systems restricted to surfaces of revolution, these are a very well model to study the termodinamical properties of microbiological systems and macromolecules lies on biological membranes such as cellular well.
arxiv  

Development of MDM2‐Targeting PROTAC for Advancing Bone Regeneration

open access: yesAdvanced Science, EarlyView.
This work presents a creative pipeline for developing MDM2‐targeting PROTACs (MDM2‐PROTACs) for application in bone regeneration. The developed PROTACs (CL144 and CL174) are validated for their degradation efficiency and osteogenic effects in human BMSCs.
Sol Jeong   +17 more
wiley   +1 more source

Mechanisms of Baicalin Alleviates Intestinal Inflammation: Role of M1 Macrophage Polarization and Lactobacillus amylovorus

open access: yesAdvanced Science, EarlyView.
Baicalin alleviates E. coli‐induced intestinal inflammation through dual mechanisms: direct inhibition of the TLR4/IRF/STAT signaling pathway to modulate macrophage polarization and antigen presentation, thereby regulating Th17/Treg cell differentiation; and microbiota‐mediated indirect effects via increasing Lactobacillus amylovorus abundance and ...
Shunfen Zhang   +10 more
wiley   +1 more source

Endosymbiotic ratchet accelerates divergence after organelle origin

open access: yesBioEssays, Volume 45, Issue 1, January 2023., 2023
Primary endosymbiosis gave rise to mitochondria and plastids. The proximate impacts of organelle origin on lineage evolution have not been addressed at the population level. Using data from the photosynthetic amoeba Paulinella, we hypothesize that primary endosymbiosis accelerates lineage divergence, a process we refer to as the endosymbiotic ratchet ...
Debashish Bhattacharya   +3 more
wiley   +1 more source

Artificial Intelligence for Microbiology and Microbiome Research [PDF]

open access: yesarXiv
Advancements in artificial intelligence (AI) have transformed many scientific fields, with microbiology and microbiome research now experiencing significant breakthroughs through machine learning and deep learning applications. This review provides a comprehensive overview of AI-driven approaches tailored for microbiology and microbiome studies ...
arxiv  

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