Results 71 to 80 of about 1,454,719 (345)
Annals of Clinical MicrobiologyAcanthamoeba species are ubiquitous, free-living organisms found in the environment. They can cause a sight-threatening cornea disease, termed Acanthamoeba keratitis, and are often misdiagnosed, causing delayed administration of the correct treatment ...
Bosung Park +4 more
doaj +1 more source
Exploitation of Aspergillus terreus for the Production of Natural Statins
Journal of Fungi, 2016 The fungus Aspergillus (A.) terreus has dominated the biological production of the “blockbuster” drugs known as statins. The statins are a class of drugs that inhibit HMG-CoA reductase and lead to lower cholesterol production.
Mishal Subhan +2 more
doaj +1 more source
Repeat Expansions in PLIN4 Cause Autosomal Dominant Vacuolar Myopathy With Sarcolemmal Features
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We aim to describe and characterize two unrelated Spanish families suffering from an autosomal dominant autophagic vacuolar myopathy caused by repeat expansions in PLIN4. Methods We evaluated the clinical phenotype and muscle imaging, and performed a genetic workup that included exome sequencing, muscle RNAseq, and long‐read genome ...
Laura Llansó +17 more
wiley +1 more source
Central Dysmyelination in SSADH‐Deficient Humans and Mice
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer +11 more
wiley +1 more source
Frontiers in Microbiology, 2016 In Europe, each year, more than four milion patients acquire a healthcare-associated infection (HAI) and almost 40 thousand die as a direct consequence of it.
A. S. Simões +6 more
semanticscholar +1 more source
Advanced Biology, EarlyView.The regenerative potential of adipose tissue‐derived stem cells can be enhanced through chemical stimulation in vitro. A short stimulation protocol using forskolin, either alone or in combination with other growth factors, under xeno‐free conditions enhanced the pro‐angiogenic responses in human ASCs.
Maria Vittoria Giraudo +5 more
wiley +1 more source
Challenges in microbiological identification of aerobic bacteria isolated from the skin of reptiles
PLOS ONE, 2020 Bacterial pathogens are often involved in dermatitis in reptiles. Exact identification of reptile-specific but otherwise uncommon bacterial species may be challenging. However, identification is crucial to evaluate the importance of the detected bacterial species.The aim of this study was to assess the number of aerobic bacterial isolates cultured from
Maria Brockmann +6 more
openaire +4 more sources
Advanced Biology, EarlyView.The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali +5 more
wiley +1 more source
New Microbes and New Infections, 2018 Acinetobacter species can be important opportunistic pathogens in humans, especially in healthcare settings. We report here the first isolation of Acinetobacter ursingii from an animal species; it was isolated from a canine urinary tract infection, and ...
S. Salavati +3 more
doaj
Clinical, Environmental, and Serologic Surveillance Studies of Melioidosis in Gabon, 2012–2013
Emerging Infectious Diseases, 2015 Burkholderia pseudomallei, an environmental gram-negative bacillus, is the causative agent of melioidosis and a bio-threat agent. Reports of B. pseudomallei isolation from soil and animals in East and West Africa suggest that melioidosis might be more ...
W. Joost Wiersinga +17 more
doaj +1 more source