Results 11 to 20 of about 20,307 (268)
Downregulated miR-181a alleviates H2O2-induced oxidative stress and cellular senescence by targeting PDIA6 in human foreskin fibroblasts [PDF]
Anais Brasileiros de Dermatologia, 2023 Background Oxidative stress is strongly associated with cellular senescence. Numerous studies have indicated that microRNAs (miRNAs) play a critical part in cellular senescence.
Yan Huang +5 more
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Glutathione Transferases as Efficient Ketosteroid Isomerases
Frontiers in Molecular Biosciences, 2021 In addition to their well-established role in detoxication, glutathione transferases (GSTs) have other biological functions. We are focusing on the ketosteroid isomerase activity, which appears to contribute to steroid hormone biosynthesis in mammalian ...
Bengt Mannervik +4 more
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Application-Oriented Marine Isomerases in Biocatalysis
Marine Drugs, 2020 The class EC 5.xx, a group of enzymes that interconvert optical, geometric, or positional isomers are interesting biocatalysts for the synthesis of pharmaceuticals and pharmaceutical intermediates.
Antonio Trincone
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Plants, 2022 Switchgrass rust caused by Puccinia novopanici (P. novopanici) has the ability to significantly affect the biomass yield of switchgrass, an important biofuel crop in the United States. A comparative genome analysis of P.
Raja Sekhar Nandety +6 more
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NmPin from the marine thaumarchaeote Nitrosopumilus maritimus is an active membrane associated prolyl isomerase. [PDF]
, 2016 We cordially thank Alma Rute for excellent technical assistance and the DFG (GRK 1431-1 and 1431-2) for financial support (PB). We thank the Microscope and Histology Facility of the University of Aberdeen for providing their equipment.
Bayer, Peter +5 more
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Vascular thiol isomerases [PDF]
Blood, 2016 AbstractThiol isomerases are multifunctional enzymes that influence protein structure via their oxidoreductase, isomerase, and chaperone activities. These enzymes localize at high concentrations in the endoplasmic reticulum of all eukaryotic cells where they serve an essential function in folding nascent proteins.
Robert, Flaumenhaft, Bruce, Furie
openaire +2 more sources
Communications Biology, 2021 Namitz, Zheng et al. identify a bivalent interaction by the yeast Ess1 with CTD peptides of RNA polymerase II. Their results suggest an anchored mechanism of isomerization, and raise the possibility of eukaryotic parvulin-class prolyl isomerases gaining ...
Kevin E. W. Namitz +6 more
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Complete Determination of the Pin1 Catalytic Domain Thermodynamic Cycle by NMR Lineshape Analysis [PDF]
, 2011 The phosphorylation-specific peptidyl-prolyl isomerase Pin1 catalyzes the isomerization of the peptide bond preceding a proline residue between cis and trans isomers.
De, Soumya +5 more
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Development of a selection system for the detection of L-ribose isomerase expressing mutants of Escherichia coli [PDF]
, 2007 L-Arabinose isomerase (E.C. 5.3.1.14) catalyzes the reversible isomerization between L-arabinose and L-ribulose and is highly selective towards L-arabinose.
Beauprez, Joeri +7 more
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Proline Isomerization: From the Chemistry and Biology to Therapeutic Opportunities
Biology, 2023 Proline isomerization, the process of interconversion between the cis- and trans-forms of proline, is an important and unique post-translational modification that can affect protein folding and conformations, and ultimately regulate protein functions and
Deepti Gurung +5 more
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