Results 31 to 40 of about 12,847 (298)
Peptidyl-prolyl cis/trans isomerases in GtoPdb v.2023.1
, 2023 Peptidyl-prolyl cis/trans isomerases (PPIases) are an enzyme family which catalyse the cis/trans isomerisation of proline peptide bonds to promote the folding and re-folding of peptides and proteins.
Robson, Tracy +3 more
core +1 more source
Cell surface thiol isomerases may explain the platelet-selective action of S-nitrosoglutathione [PDF]
, 2011 S-nitrosoglutathione (GSNO) at low concentration inhibits platelet aggregation without causing vasodilation, suggesting platelet-selective nitric oxide delivery. The mechanism of this selectivity is unknown, but may involve cell surface thiol isomerases,
Gordge, M.P. +5 more
core +1 more source
Is EC class predictable from reaction mechanism?
BMC Bioinformatics, 2012 Background We investigate the relationships between the EC (Enzyme Commission) class, the associated chemical reaction, and the reaction mechanism by building predictive models using Support Vector Machine (SVM), Random Forest (RF) and k-Nearest ...
Nath Neetika, Mitchell John BO
doaj +1 more source
The evolution of enzyme function in the isomerases. [PDF]
, 2014 The advent of computational approaches to measure functional similarity between enzymes adds a new dimension to existing evolutionary studies based on sequence and structure.
Thornton, Janet M +4 more
core +1 more source
The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression
Hepatology, EarlyView., 2022 Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro +14 more
wiley +1 more source
A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance
Nature Communications, 2017 Bacterial disulfide isomerases shuffle incorrect disulfide bonds. Here, the authors structurally characterize the disulfide isomerase ScsC fromProteus mirabilisand identify a functionally important shape-shifting motif that allows ScsC to adopt a diverse
Emily J. Furlong +11 more
doaj +1 more source
THIOL ISOMERASES – A POSSIBLE TARGET FOR THROMBOSIS CONTROL
Рациональная фармакотерапия в кардиологии, 2017 While there are an increasing number of antithrombotic agents with demonstrated clinical efficacy, thrombosis remains the leading cause of mortality in developed countries. Therefore, there is a need further development of therapies targeting alternative
I. V. Gribkova, M. V. Davydovskaya
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2022 Bacterial AB-type toxins are proteins released by the producing bacteria and are the causative agents for several severe diseases including cholera, whooping cough, diphtheria or enteric diseases.
Katharina Ernst
doaj +1 more source
Peptidyl-prolyl cis/trans isomerases in GtoPdb v.2021.2
, 2021 Peptidyl-prolyl cis/trans isomerases (PPIases) are an enzyme family which catalyse the cis/trans isomerisation of proline peptide bonds to promote the folding and re-folding of peptides and proteins.
Robson, Tracy, Annett, Stephanie
core +1 more source
Identification and Characterization of (3Z):(2E)-Hexenal Isomerases from Cucumber
Frontiers in Plant Science, 2017 E-2-hexenal is a volatile compound that is commonly emitted by wounded or stressed plants. It belongs to the group of so-called green leaf volatiles (GLVs), which play an important role in transferring information to plants and insects.
Eleni A. Spyropoulou +7 more
doaj +1 more source