Results 181 to 190 of about 9,503 (262)

Dopant‐Tailored Matrices: A Crystal Engineering Strategy for Organic Room‐Temperature Phosphorescent Host–Guest Systems and Beyond

open access: yesAngewandte Chemie, EarlyView.
Rather than selecting dopants to match a pre‐existing host matrix, the dopant‐tailored matrix strategy involves rational engineering of host matrices around a preselected class of dopants by targeting matrix packing motifs that promote synergistic host‐dopant interactions upon doping.
Catherine Demangeat   +7 more
wiley   +1 more source

Borylcyclopropanes: Synthetic Strategies and Applications

open access: yesAngewandte Chemie, EarlyView.
Borylcyclopropanes (cyclopropanes bearing a boron substituent) sit at the intersection of two privileged frameworks in synthesis. This review provides the first exhaustive survey of their chemistry, spanning metal–carbene, nucleophilic cyclization, radical, hydroboration, and C─H activation routes, and documenting applications in medicinal chemistry ...
Aiza A. Butt, Joseph M. Ready
wiley   +1 more source

Chemoenzymatic Radiosynthesis of a Gluconate Transporter‐Targeted In Vivo Bacterial Sensor From Clinical [18F]FDG

open access: yesAngewandte Chemie, EarlyView.
An efficient radiosynthesis of fluorine‐18 labeled gluconic acid ([18F]FGA) was developed using two readily available materials, 2‐deoxy‐2‐[18F]fluoro‐D‐glucose ([18F]FDG) and glucose oxidase. [18F]FGA is highly specific for bacterial gluconate metabolism mediated by gluconate permease (GntP) and gluconate kinase (GntK), with rapid clearance, low off ...
Sang Hee Lee   +7 more
wiley   +1 more source

Isosteric Engineering of Enzymes: Overcoming Activity–Stability Trade‐Offs by Site‐Selective CH → N Substitutions

open access: yesAngewandte Chemie, EarlyView.
Coupling biosynthetic noncanonical amino acid production with genetic code expansion enables site‐specific incorporation of azatryptophans into PET‐degrading enzymes (PETases). By isosteric single‐atom editing of a conserved tryptophan, AzaPETases break the activity–stability trade‐off, delivering higher catalytic efficiency at elevated temperature and
Elwy H. Abdelkader   +3 more
wiley   +1 more source

Regiodivergent Deuteration of Pyridine-Based Heterocycles. [PDF]

open access: yesOrg Lett
Du W   +4 more
europepmc   +1 more source

A Multi‐Stimuli Transformational Network of Benzil‐Based Pd(II) Assemblies

open access: yesAngewandte Chemie, EarlyView.
Incorporation of a flexible and chemically reactive benzil backbone into the ligand structure allows it to access multiple conformations, enabling the formation of diverse homo‐ and heteroleptic Pd(II) assemblies with different nuclearities and topologies.
Zhiwei Zeng   +5 more
wiley   +1 more source

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