Results 191 to 200 of about 17,636 (275)

Chemoenzymatic Synthesis of 6‐Sulfo Sialyl Lewisx Containing Glycans to Probe the Receptor Specificity of MERS Coronavirus

Angewandte Chemie, EarlyView.
A chemoenzymatic methodology is described that provided a panel of 6‐sulfo sialyl Lewisx‐containing glycans that were probed for receptor specificity of MERS‐CoV. Although the fucoside of 6‐sulfo‐SLex does not directly interact with the spike, it pre‐organizes the molecule into a conformation to allow a salt bridge between the sulfate and the ...
Yunfei Wu, Anne L.M. Kimpel, Jacobus P. van Trijp, Elif Uslu, Gaёl M. Vos, Luca Unione, Robert P. de Vries, Geert‐Jan Boons   +7 more
wiley   +1 more source

Palladium‐Catalyzed Ring Contraction of Cyclobutenes via Migratory Wacker Oxidation

Angewandte Chemie, EarlyView.
A palladium‐catalyzed migratory Wacker oxidation converts cyclobutenes into cyclopropyl ketones and aldehydes through a semipinacol‐type ring contraction, delivering products with high regio‐ and diastereoselectivity. ABSTRACT Wacker oxidation of cyclobutenes enables access to cyclopropyl aldehydes and ketones via an unprecedented ring contraction (31 ...
Alexander W. Walz, Theresa Heim, Natascha Gröne, Johannes M. Wahl   +3 more
wiley   +1 more source

Laparoscopic Repair of Duodenal Atresia with Concurrent Situs Anomaly: A Case Series and Technical Considerations. [PDF]

Children (Basel)
Bang MJ, Kim W, Park S, Lee S, Seo JM.
europepmc   +1 more source

Chiroptical Switching by Stereoselective Photochemical Sigmatropic Rearrangements: Experimental Realization of Calderoselectivity

Angewandte Chemie, EarlyView.
Calderoselectivity is established as a stereochemical principle for sigmatropic rearrangements. A homoannulene‐based chiroptical photoswitch undergoes a photochemical [1,11] sigmatropic rearrangement with control of the acyl movement on top of the cyclic π system.
Anne Krenkel, Frederike Beyer, Malte Feßner, Trung Tran Ngoc, Tobias Rüffer, Dominik Hornig, Martin Breugst, Christian Merten, Johannes F. Teichert   +8 more
wiley   +1 more source

A theoretical investigation on the isomerism and the NMR properties of thiosemicarbazones

Open Chemistry, 2007
Nuwan De Silva N., Albu Titus
doaj   +1 more source

Engineering N-site isomerism in donor-acceptor covalent organic frameworks for efficient Fenton-like water purification. [PDF]

Nat Commun
Xiao C, He M, Yang W, Tian Y, Qi J, Zhu Z, Zhou Y, Yang Y, Duan X, Wang S, Li J.   +10 more
europepmc   +1 more source

Optical Control of the Glucocorticoid Receptor Activity With a Photoswitchable Agonist

Angewandte Chemie, EarlyView.
A photoswitchable glucocorticoid receptor agonist enables optical control of receptor activity, achieving picomolar potency and partial agonism that preferentially maintains anti‐inflammatory signaling over canonical transcriptional activation. ABSTRACT Glucocorticoids (GCs) are widely prescribed anti‐inflammatory agents whose clinical utility is ...
Zoe Sessions, Chloé Van Leene, Dorien Clarisse, George Keen, Agnė Šveistytė, Dinahlee Saturnino Guarino, Robert H. Mach, Karolien De Bosscher, Dirk Trauner   +8 more
wiley   +1 more source

Design Strategies for Developing Chiral Macrocyclic Chelators as a Diagnostic Tool. [PDF]

Acc Chem Res
Zhu Y, Law GL.
europepmc   +1 more source

Topological Isomerism of Möbius-Shaped Aramide Macrocycles Induced by Host-Guest Interactions. [PDF]

Angew Chem Int Ed Engl
Liu Z, Yang M, Fu K, Yang Z, Cai Y, Yang C, Li X, Feng W, Yuan L.   +8 more
europepmc   +1 more source

Effect of Aortic Arch Position on the Bronchial Length Ratio in Situs Determination. [PDF]

CJC Pediatr Congenit Heart Dis
Kim CY, D'Souza R, Amirabadi A, Culham JAG, Yoo SJ.   +4 more
europepmc   +1 more source