Light‐Controlled Modulation of 15‐Lipoxygenase‐1 Regulates Intestinal Inflammatory Signaling
The developed target‐guided strategy enables the rational design of diazo‐based photoswitchable inhibitors of 15‐lipoxygenase‐1. Distinct molecular architectures program opposite light‐dependent activity, allowing on‐demand control of enzyme inhibition.
Anastasia Louka +10 more
wiley +1 more source
Resolving Isomeric Structures in Natural Complex Carbohydrates: A Comparative Study of SLIM and Cyclic Ion Mobility Platforms. [PDF]
Benazza R +5 more
europepmc +1 more source
Within the same molecular length scale, antiaromatic s‐indacene exhibits a marked increase in conductance compared to its aromatic benzodithiophene counterpart. Notably, the inherently small HOMO–LUMO gap of antiaromatic systems maintains a certain level of conductance even in the presence of cross‐conjugation.
Ching‐Piao Chu +8 more
wiley +1 more source
Comment on Othman et al. Ventricular Topology in Congenital Heart Defects Associated with Heterotaxy: Can We Find Patterns Reflecting the Syndrome-Specific Tendency for Visceral Symmetry? <i>J. Cardiovasc. Dev. Dis.</i> 2025, <i>12</i>, 430. [PDF]
Pugnaloni F, Calcagni G, Marino B.
europepmc +1 more source
A Borane Sandwich Analogue of Ferrocene
The first ferrocene analogue with two boron‐based ligands is identified through a global exploration of the FeB10H20 potential energy surface. The η5,η5‐Fe(B5H10)2 complex emerges as the global minimum, showing that metal coordination inverts borane stability and enables aromatic boron rings inaccessible in isolation.
Viviana Roman‐Ventura +8 more
wiley +1 more source
Isomerism of the right atrial appendages with bilateral eparterial bronchi: clinical challenges and surgical management guided by 3D cardiac computed tomography. [PDF]
Shah J, Pathuri S, Richardson R.
europepmc +1 more source
Geometric Nonuniformity Localizes Valence Orbitals in Gold Clusters: Case Study on [Au23(SC6H11)16]–
The electronic structure of [Au23(SC6H11)16]–, a monolayer‐protected gold cluster with a nonuniform Au13 core, was investigated. Anion photoelectron spectroscopy and density functional theory calculations revealed that the highest occupied molecular orbital (HOMO) and HOMO‐1 are localized on the two triangular Au3 units at the ends of the Au13 core ...
Yosuke Asami +3 more
wiley +1 more source
Asymmetric Iron‐Catalyzed Vicinal C(sp3)─H Diamination of Carboxylic Acids
An iron‐catalyzed vicinal α,β‐C(sp3)─H diamination of readily available carboxylic acids furnishes chiral α,β‐diamino acids in a single pot with high regio‐, diastereo‐, and enantioselectivity (up to >20:1 dr and >99% ee). ABSTRACT The direct construction of chiral 1,2‐diamines through the stereoselective functionalization of two vicinal C(sp3)─H bonds
Bing Zhou +5 more
wiley +1 more source
Polysplenia syndrome with semi-annular pancreas, midgut malrotation and interrupted inferior vena cava: A rare adult case report. [PDF]
Bassel SA +6 more
europepmc +1 more source

