Results 161 to 170 of about 174,602 (303)

Computational perspective on structure, energetics, and bonding of FeC₂O isomers with astrochemical significance. [PDF]

Front Chem
R J A, Rajasabai SP.
europepmc   +1 more source

A Novel Constitutional TUBB Variant Associated With Familial Malformations of Cortical Development

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Most pathogenic tubulin variants arise de novo in sporadic patients, causing severe brain malformations and significant neurodevelopmental impairment. The resulting reproductive disadvantage typically prevents these mutations from being transmitted to offspring.
Elena Cellini, Davide Mei, Mara Cavallin, Simona Fiori, Luciana Tramacere, Maria Elena Melica, Giulia Antonelli, Simona Virdò, Elena Parrini, Renzo Guerrini   +9 more
wiley   +1 more source

Modular and Stereoselective Synthesis of Cyclobutane β‐Amino Alcohols

Angewandte Chemie, EarlyView.
Late‐stage functionalization and photoisomerization of 1,2‐azaborine leads to a general strategy for the synthesis of diversely substituted cyclobutane β‐amino alcohols. The relative stereochemistry of the resulting products is unambiguously defined by the stereospecific and stereoselective nature of the photoisomerization‐hydrogenation‐oxidation ...
Xinyu Yang, Tomoya Ozaki, Bo Li, Shih‐Yuan Liu   +3 more
wiley   +2 more sources

Mapping Double-Bond Positional Isomers of Phosphatidylcholines in Zebrafish Using OzMALDI Mass Spectrometry Imaging. [PDF]

J Am Soc Mass Spectrom
Weerasinghe SM, Rensner JJ, Essner JJ, Lee YJ.   +3 more
europepmc   +1 more source

Spectrum of Congenital Anomalies in Myhre Syndrome—Insights Into Effects Brought by Altered TGF‐β Signaling via Gain‐of‐Function Variants in SMAD4

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome is a rare genetic disorder characterized by progressive multisystem involvement. Gain‐of‐function missense heterozygous variants affecting the Ile500 residue and Arg496 residue of the SMAD4 gene are implicated in this condition.
Kawmadi Gunawardena, Alessandro De Falco, Deborah Osio, Eleanor Sherlock, Emma Kivuva, Erina Sasaki, Francis H. Sansbury, Nayana Lahiri, Patricia Foley, Sahar Mansour, Shane McKee, Tazeen Ashraf, Nicola Brunetti‐Pierri, Usha Kini   +13 more
wiley   +1 more source

In Silico Isomerization Produces Apt Negative Data for VHTS Validation. [PDF]

J Chem Inf Model
Ivanov SM.
europepmc   +1 more source

LC-Triple Quadrupole MS Enables Sample Classification in <i>Viscum combreticola</i>: Detecting Subtle Photochemical Isomerization in Hydroxycinnamic Acid Derivatives. [PDF]

J Anal Methods Chem
Sekgobela MR, Ramabulana AT, Mathomu LM, Moyo B, Madala NE.   +4 more
europepmc   +1 more source

Synthesis, Structural Elucidation, and Anticancer Efficacy Evaluation of a Novel Nd(III)-Schiff Base Complex: Experimental and Computational Insights. [PDF]

Chem Biodivers
Balboul BAA, Taha RH, Alali I, Alhathlaul N, Alsirhani AM, Saleh AM, Yousef TA, Benassi E.   +7 more
europepmc   +1 more source

Cysteine Thioaldehydes: Photolytic Generation, Reactivity, and Biological Implications

Angewandte Chemie, EarlyView.
Photolysis of cysteine phenacylsulfides bearing non‐conjugating electron‐withdrawing substituents leads to high conversions into cysteine thioaldehydes through a Norrish type‐II pathway. This methodology enabled the study of the aqueous reactivity of these important biosynthetic intermediates, which, depending on peptide sequence, pH and buffer ...
Ardra Karthika, Matthew Murray, Guillermo Palop, Lee‐Ann J. Keane, Patrick McArdle, Nicholas D. J. Yates, Christopher D. Spicer, Alison Parkin, Martin A. Fascione, Eddie L. Myers   +9 more
wiley   +1 more source

Microwave-Assisted Natural Catalyst-Promoted Astaxanthin <i>Z</i>‑Isomerization in Deep Eutectic Solvent Systems. [PDF]

ACS Omega
Han L, Lin L, Xu H, Hu Q, Xie D.
europepmc   +1 more source