Results 201 to 210 of about 403,555 (400)

The Separation of Structural Isomers using a Magneto-Archimedes Method

open access: diamond, 2017
Tatsuya Mori   +4 more
openalex   +2 more sources

Effect of Chiral Isomers Quinidine and Quinine Analogues on CYP2D6 Inhibition - A QSAR Investigation

open access: yes, 2008
Quinidine and quinine are the chiral isomers and CYP2D6 inhibitors. The stereochemistry difference results in the different inhibitory activity with quinidine being 2 orders of magnitude more potent than quinine.
艾纯芝, 杨凌, 邹汉法
core  

Use of Photo Isomers to Enhance the Removal of Lignin from Woody Biomass Hydrolysate

open access: green, 2023
Dipesh Karki   +3 more
openalex   +1 more source

NACE–ESI‐MS/MS method for separation and characterization of phosphorylation and acylation isomers of lipid A [PDF]

open access: hybrid, 2020
Viktor Sándor   +5 more
openalex   +1 more source

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

open access: yesAngewandte Chemie, EarlyView.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources

Catalytic Enantioselective Multicomponent Reactions of Sulfoxonium Ylides Enabled by a Formal Rearrangement—A Versatile Entry to Enantioenriched α‐Sulfanyl Carbonyl Compounds

open access: yesAngewandte Chemie, EarlyView.
A catalytic network embedding a formal rearrangement enables the first catalytic enantioselective multicomponent reaction (MCR) of sulfur ylides. In the presence of a bulky chiral phosphoric acid, the reaction combines sulfoxonium ylides, aldehydes and thiols, and affords synthetically versatile β‐hydroxy‐α‐sulfanyl carbonyl compounds in ...
Nicolò Santarelli   +10 more
wiley   +2 more sources

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