Results 191 to 200 of about 1,705 (235)
Pyrithidium and isometamidium in the treatment of canine trypanosomiasis due to Trypanosoma brucei.
, 1970 Saydil Touré
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Rational drug use: To better manage trypanosomosis and trypanocide resistance
, 2015 Grace, Delia
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[Prothidium and isometamidium as drugs against Trypanosomia brucei in dogs].
Revue d'elevage et de medecine veterinaire des pays tropicaux, 1971 openaire +1 more source
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Veterinary Parasitology, 2002
A survey to monitor the use of trypanocidal drugs by cattle breeders was conducted in Zambia. Use was made of a questionnaire and of the isometamidium-ELISA technique. One hundred and twenty-two farmers and 50 veterinary assistants were interviewed. The isometamidium-ELISA was used to monitor the isometamidium serum concentration in 72 cattle, 1 week ...
V Delespaux +2 more
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A survey to monitor the use of trypanocidal drugs by cattle breeders was conducted in Zambia. Use was made of a questionnaire and of the isometamidium-ELISA technique. One hundred and twenty-two farmers and 50 veterinary assistants were interviewed. The isometamidium-ELISA was used to monitor the isometamidium serum concentration in 72 cattle, 1 week ...
V Delespaux +2 more
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A comparative study of the pharmacokinetics of isometamidium chloride in sheep and goats
Small Ruminant Research, 2004Abstract A study was carried out to determine and compare the pharmacokinetics of isometamidium in groups of six animals each of sheep and goats treated by intramuscular injection with isometamidium chloride (Samorin ® , Rhone Merieux, Lyon, France) at 0.5 mg/kg body weight.
T W Jones
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Journal of Pharmaceutical and Biomedical Analysis, 1998
The determination of the phenanthridine trypanocide, isometamidium chloride hydrochloride (ISM), in the presence of four process-related and degradation impurities, by RP-HPLC using a Licrospher-60 RP-select B column with a mobile phase composition of acetonitrile/KH2PO4 (PH 3.0, 20 mM) (25:75 v/v) with UV detection at 320 nm, is described.
G G Skellern, M H Grant, J M Midgley
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The determination of the phenanthridine trypanocide, isometamidium chloride hydrochloride (ISM), in the presence of four process-related and degradation impurities, by RP-HPLC using a Licrospher-60 RP-select B column with a mobile phase composition of acetonitrile/KH2PO4 (PH 3.0, 20 mM) (25:75 v/v) with UV detection at 320 nm, is described.
G G Skellern, M H Grant, J M Midgley
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Development of a radioimmunoassay for isometamidium
Veterinary Research Communications, 1988A radioimmunoassay for the trypanocidal drug isometamidium (ISMM) has been developed using antibodies produced in sheep immunized against the drug cross-linked to human serum albumin. With 14C-ISMM as a radioligand, cross-reactivity of the antibodies was determined and found to be less than 3% with pyrithidium, diminazene and quinapyramine and about 13%
L D, Kinabo, J A, Bogan
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Effect of isometamidium on Trypanosoma congolense infectivity
Veterinary Parasitology, 1991Isometamidium chloride (Samorin, RMB, England) is a widely used and highly effective trypanocide for the treatment of bovine trypanosomiases. However, the appearance of isometamidium-resistant populations of T. congolense in Africa makes it necessary to develop methods for the rapid and reliable detection of drug resistance in the laboratory. Currently
I A, Sutherland, A, Mounsey, P H, Holmes
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Pharmacokinetic and histopathological investigations of isometamidium in cattle
Research in Veterinary Science, 1988The absorption and distribution patterns of the trypanocidal drug isometamidium and its effect on tissues in cattle were characterised. After intramuscular administration of a prophylactic dose of 0.5 mg kg-1 bodyweight, the drug was rapidly detectable in serum at a mean maximum concentration of only 20 ng ml-1 and declined to concentrations of lower ...
L D, Kinabo, J A, Bogan
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