Results 211 to 220 of about 1,705 (235)

Pharmacokinetics and efficacy of isometamidium chloride against Trypanosoma vivax in cattle

Parasitology International
We evaluated the pharmacokinetics (pk), preventive efficacy (PE) and therapeutic efficacy (TE) of isometamidium chloride (ISM) against T. vivax. For the pk study, the animals received ISM 1 mg/kg (1 mL/40 kg) on day 0 and plasma samples were collected at day 0 (immediately before treatment), 1 h, 3 h 6 h, 9 h and 12 h after treatment, D + 1 (24 h and ...
Luiz Fellipe Monteiro, Couto, Dina Maria Beltrán, Zapa, Luciana Maffini, Heller, Thiago Souza Azeredo, Bastos, Luis Fernando, Vettorato, Heitor de Oliveira Arriero, Amaral, Rafael Marin, Chiummo, Daniel de Castro, Rodrigues, Vando Edésio, Soares, Lorena Lopes, Ferreira, Welber Daniel Zanetti, Lopes   +10 more
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Action of isometamidium chloride on the insect vector form of Trypanosoma vivax

Research in Veterinary Science, 1985
The effect of isometamidium chloride upon developing and mature Trypanosoma vivax occurring in Glossina palpalis palpalis flies was evaluated. Newly emerged G p palpalis flies were infected with T vivax by allowing them to feed on parasitaemic animals. Two experiments were conducted and in each the flies were divided into two groups.
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Chromatographic and spectroscopic analysis of the components present in the phenanthridinium trypanocidal agent isometamidium

Analytical and Bioanalytical Chemistry, 2014
The chromatographic isolation and characterisation of the four compounds present in the quaternary phenanthridine veterinary trypanocidal agent, isometamidium chloride hydrochloride (ISM), is reported. The isolated compounds were unambiguously characterised using spectroscopic (NMR, UV, IR and MS) methods as 3-amino-8-[3-(3-carbamimidoyl-phenyl ...
John O, Igoli, Gavin, Blackburn, Alexander I, Gray, Oliver B, Sutcliffe, David G, Watson, Melvin R, Euerby, Graham G, Skellern   +6 more
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The pharmacology of isometamidium

Journal of Veterinary Pharmacology and Therapeutics, 1988
L D, Kinabo, J A, Bogan
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Some observations on the toxicosis of isometamidium chloride (samorin) in camels.

Veterinary and human toxicology, 1986
Healthy camels were experimentally infected with Trypanosoma evansi and then treated with isometamidium chloride (samorin) at single intravenous doses of 0.5 or 1.0 mg/kg. Five to 10 min after the drug administration, the camels at both dosages showed lacrimation, salivation, trembling, restlessness, frequent urination and defecation, followed by ...
B H, Ali, T, Hassan
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Studies on isometamidium

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1963
J. Hill, J.A. McFadzean
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Binding of isometamidium to calf thymus DNA and lipids: pharmacological implications

Journal of Veterinary Pharmacology and Therapeutics, 1987
L D, Kinabo, J A, Bogan
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Comparison of isometamidium chloride and homidium bromide as prophylactic drugs for trypanosomiasis in cattle at Nguruman, Kenya

Acta Tropica, 1995
Michael M Gicheru
exaly  

STUDIES ON ISOMETAMIDIUM. DEPOTS OF ISOMETAMIDIUM IN MICE AND RATS AND THEIR IMPORTANCE FOR PROPHYLAXIS AGAINST TRYPANOSOMA CONGOLENSE.

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1996
J, HILL, J A, MCFADZEAN
openaire   +1 more source

Synthesis and evaluation of isometamidium-alginate nanoparticles on equine mononuclear and red blood cells

International Journal of Biological Macromolecules, 2016
Meenu Chopra, Neeraj Dilbaghi, Rajender Kumar   +2 more
exaly