Results 21 to 30 of about 474 (132)

French guyanan stock of Trypanosoma vivax resistant to diminazene aceturate but sensitive to isometamidium chloride

Acta Tropica, 1995
An isolate of T. vivax was collected from a naturally infected Zebu in French Guyana. The isolate was subsequently shown to produce pathogenic infections in both Taurine and Zebu cattle. However, its sensitivity of the population to diminazene aceturate and isometamidium chloride was determined since these are the most commonly used anti-trypanosomal ...
Andrew Peregrine, M Desquesnes, A S Peregrine   +2 more
exaly   +5 more sources

Managing African animal trypanosomiasis in Benin: Knowledge, attitudes, and practices of cattle owners in the West Atacora zone [PDF]

Veterinary World
Background and Aim: African animal trypanosomiasis (AAT), transmitted by tsetse flies, severely constrains livestock productivity in sub-Saharan Africa.
Yao Akpo, Aretas B. N. Tonouhewa, Traore Alkoiret, Marc T. Kpodekon   +3 more
doaj   +2 more sources

Trypanocide Use and Molecular Characterization of Trypanosomes Resistant to Diminazene Aceturate in Cattle in Northern Côte D’Ivoire [PDF]

Tropical Medicine and Infectious Disease
The resistance of trypanosomes to the doses of trypanocide administered by farmers to their animals acts as a real brake on efforts to control to combat African trypanosomiasis.
Jean-Yves Ekra, Eliakunda Michael Mafie, Henri Sonan, Michael Kanh, Biégo Guillaume Gragnon, Edouard K. N’Goran, Jagan Srinivasan   +6 more
doaj   +2 more sources

Systematic Review and Meta-Analysis on Knowledge Attitude and Practices on African Animal Trypanocide Resistance [PDF]

Tropical Medicine and Infectious Disease, 2022
Background: African trypanocide resistance is an emerging public health emergency whose control requires a revisit on farmer’s knowledge, attitudes, and practices in developing countries.
Keneth Iceland Kasozi, Ewan Thomas MacLeod, Charles Waiswa, Michael Mahero, Ibrahim Ntulume, Susan Christina Welburn   +5 more
doaj   +2 more sources

The economic cost of bovine trypanosomosis in pastoral and ago pastoral communities surrounding Murchision Falls National park, Buliisa district, Uganda [PDF]

BMC Veterinary Research, 2022
Background: Animal diseases that are endemic like tsetse transmitted trypanosomosis cause the continuous expenditure of financial resources of livestock farmers and loss of productivity of livestock.
Daniel Kizza, Michael Ocaido, Anthony Mugisha, Rose Azuba, Sylvia Nalubwama, Sarah Nalule, Howard Onyuth, Simon Peter Musinguzi, Charles Waiswa   +8 more
doaj   +2 more sources

Longitudinal observational (single cohort) study on the causes of trypanocide failure in cases of African animal trypanosomosis in cattle near wildlife protected areas of Northern Tanzania. [PDF]

PLoS Neglected Tropical Diseases
African animal trypanosomosis (AAT) in cattle is primarily managed through trypanocide administration and insecticide application. Trypanocides can be used for both treatment and prophylaxis, but failure is often reported; this may occur due to ...
Shauna Richards, Davide Pagnossin, Paul Samson Buyugu, Oliver Manangwa, Furaha Mramba, Emmanuel Sindoya, Edith Paxton, Steve J Torr, Ryan Ritchie, Giovanni E Rossi, Lawrence Nnadozie Anyanwu, Michael P Barrett, Liam J Morrison, Harriet Auty   +13 more
doaj   +2 more sources

The accumulation and compartmentalization of isometamidium chloride in Trypanosoma congolense, monitored by its intrinsic fluorescence. [PDF]

Biochem J, 1995
Interaction of the trypanocide isometamidium chloride with components of Trypanosoma congolense results in characteristic shifts in the intrinsic fluorescence of the drug. The specificity of this interaction was investigated by analysing the effects of various physicochemical manipulations on its fluorescence properties.
Wilkes JM, Peregrine AS, Zilberstein D.
europepmc   +4 more sources

The effect of diminazene aceturate and isometamidium chloride on cultured procyclic forms of susceptible and drug-resistant Trypanosoma congolense

Acta Tropica, 1991
Cultures of insect forms of Trypanosoma congolense stocks and clones with different susceptibilities to trypanocidal drugs in vivo were initiated from bloodstream trypomastigotes harvested from mammalian hosts and maintained axenically in vitro at 27 degrees C. Growth inhibition of procyclic forms of susceptible and drug-resistant T.
R Kaminsky
exaly   +4 more sources

Equine trypanosomiasis, a systematic review: Disease management. [PDF]

Equine Vet J
Abstract Background Equine trypanosomiasis is a neglected protozoal disease. Objectives To answer the study question: In equines what are the effects of disease management of trypanosomiasis on disease severity (individual level) and disease prevalence (population level) compared to no intervention? Study Design Systematic review.
Raftery AG, Gummery L, Garcia K, Mohite D, Capewell P, Sutton D.   +5 more
europepmc   +2 more sources

Pathogenic Significance of Trypanosomatids: Progress in Drug Resistance, Control Strategies, and Artificial Intelligence. [PDF]

Interdiscip Perspect Infect Dis
Trypanosomatids, including the genera Trypanosoma and Leishmania, are protozoan parasites of significant medical and veterinary relevance. These organisms cause African trypanosomiasis, Chagas disease, and leishmaniasis, which are classified as neglected tropical diseases (NTDs).
Amisigo CM, Dofuor AK, Yamoah JAA, Aiduenu AF, Gayi BK, Akomea A, Alidu ZL, Danso G, Ayivi-Tosuh SM, Quartey NK, Osei JHN, Loh SK, Ekloh W.   +12 more
europepmc   +2 more sources