Results 141 to 150 of about 99,309 (305)
Evaluation of hepatotoxicity in elderly with HIV/AIDS using isoniazid [PDF]
Claudinei Alves Santana +1 more
openalex +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery
This work is a comprehensive revision of bioactive glasses (BGs), pioneered by Prof. L.L. Hench, which are key in bone repair and regenerative medicine. Sol–gel methods and mesoporous designs enhanced their bioactivity, ions, and drug delivery. BGs now support gene therapy and 3D‐printed scaffolds, enabling personalized, multifunctional treatments in ...
Natividad Gómez‐Cerezo +3 more
wiley +1 more source
Novel nitro‐substituted diaryl 1,3,4‐ and 1,2,4‐oxadiazoles were synthesised via molecular hybridisation of bioactive heterocycles. Selected derivatives exhibited potent antimicrobial activity, including against Mycobacterium tuberculosis and Staphylococcus aureus, and cholinesterase inhibitory activity, with promising selectivity.
Enikő Šikorová +9 more
wiley +1 more source
Rifamycin drugs as alternatives to standard isoniazid treatment to prevent active tuberculosis (TB) in HIV-negative people at risk of developing active TB [PDF]
M S Jawahar, Soumya Swaminathan
openalex +1 more source
Objective Patients with systemic lupus erythematosus (SLE) experience photosensitivity, with exposure to UVB light driving lupus flares and triggering symptoms like joint pain, fatigue, and cutaneous lesions. Although the mechanism(s) linking UVB exposure to systemic effects are unclear, type I interferons (IFNs) are known to play a role.
Gantsetseg Tumurkhuu +17 more
wiley +1 more source
ABSTRACT Solid organ transplant recipients are at increased risk of acquiring serious infections. We present a case of a 48‐year‐old male with a history of renal transplantation in 2012, chronic kidney disease (CKD) Stage 4, hypertension, uncontrolled diabetes mellitus, and prior tuberculous pleural effusion.
Sakib Abrar +3 more
wiley +1 more source
Introduction: Isoniazid-induced seizure, often described as Status Epilepticus (SE), is an emergency condition characterized by repeated convulsive episodes that responds poorly to the currently available anticonvulsant drugs.
Stephen Asehinde +5 more
doaj
Coexistence of Scrofuloderma and Lepromatous Leprosy in Reaction: A Case Report
ABSTRACT Leprosy and tuberculosis (TB) are both chronic granulomatous infections caused by bacilli of the genus Mycobacterium. The simultaneous occurrence of cutaneous tuberculosis and leprosy is rare. We report a 56‐year‐old male presenting with painful erythematous nodules and plaques over the face and extremities for 1 week, along with asymptomatic ...
Anupa Khadka +3 more
wiley +1 more source
Protective Effects of Quercetin against Isoniazid and Rifampicin Induced Hepatotoxicity in Rats
Gulala Qader +4 more
openalex +1 more source

