Results 101 to 110 of about 2,755,321 (217)

Validation of an UHPLC–MS/MS Assay for the Quantification of Isoniazid and Four Major Metabolites in Human Plasma

Biomedical Chromatography, Volume 40, Issue 9, September 2026.
ABSTRACT Isoniazid (INH) is a key component of tuberculosis treatment regimens but is also associated with hepatotoxicity. This toxicity is mediated in part by its metabolites, but some degrade rapidly in plasma. A rapid freeze/thaw process with a methanol protein precipitation extraction was developed to slow the rapid degradation of acetylisoniazid ...
David Nerguizian, Brandon Klein, Farah Abdelmawla, Joe Gomez, Peter L. Anderson, Lane Bushman, Kristina M. Brooks   +6 more
wiley   +1 more source

A framework mapping factors influencing isoniazid preventive therapy adherence in Kigali, Rwanda.

, 2019
A framework mapping factors influencing isoniazid preventive therapy adherence in Kigali, Rwanda.
Angèle Musabimana (6321209), Stephen Michael Graham (5620802), Francine Mwayuma Birungi (6321203), Jeannine Uwimana (6321206), Brian van Wyk (3079650)   +4 more
core   +1 more source

In Silico and In Vitro Evaluation of Atriplex halimus: Antibacterial Activity, Molecular Docking, ADMET Profiling, and Cytotoxicity Assessment

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Atriplex halimus aqueous and hydroethanolic extracts, rich in trans‐cinnamic acid, catechin, epigallocatechin, and vitamin C. The Extracts showed modest antibacterial activity against Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa, and dose‐dependent cytotoxicity in Artemia salina.
Mohammed Roubi, Ayoub Farihi, Mohammed Dalli, Salah‐eddine Azizi, Raffaele Conte, Mohammed F. Hawaal, Abdullah R. Alonazi, Amama Rani, Bonglee Kim, Nadia Gseyra, Ramzi A. Mothana   +10 more
wiley   +1 more source

Distal sensory polyneuropathy in HIV/TB co-infection : the role of vitamin B6 and N-acetyltransferase 2 genetic variation [PDF]

, 2012
Both human immunodeficiency virus (HIV) infection and tuberculosis (TB) are complicated by a painful distal sensory polyneuropathy (DSP) that may be due to virus-related HIV-DSP, antiretroviral toxic neuropathy (ATN) or isoniazid-induced peripheral ...
Centner, Chad
core   +1 more source

Characteristics of child contacts who started isoniazid preventive therapy by adherence group (N = 84).

, 2019
Characteristics of child contacts who started isoniazid preventive therapy by adherence group (N = 84).
Angèle Musabimana (6321209), Stephen Michael Graham (5620802), Francine Mwayuma Birungi (6321203), Jeannine Uwimana (6321206), Brian van Wyk (3079650)   +4 more
core   +1 more source

Tuberculosis incidence rates during 8 years of follow-up of an antiretroviral treatment cohort in South Africa: comparison with rates in the community. [PDF]

, 2012
BACKGROUND: Although antiretroviral therapy (ART) is known to be associated with time-dependent reductions in tuberculosis (TB) incidence, the long-term impact of ART on incidence remains imprecisely defined due to limited duration of follow-up and ...
Kaplan, Richard, Lawn Stephen D., Gupta, Ankur, Ankur Gupta, Linda-Gail Bekker, Wood Robin, Kaplan Richard, Lawn, Stephen D, Robin Wood, Bekker, Linda-Gail, Stephen D Lawn, Bekker Linda-Gail, Richard Kaplan, Gupta Ankur, Wood, Robin   +14 more
core   +1 more source

Tuberculosis Misdiagnosed as Bronchogenic Carcinoma: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT The patient, a 77‐year‐old male smoker, presented to the Emergency Department with dyspnea, cough, fever, night sweats, and 12 kg weight loss, initially suggesting COPD or lung cancer. Chest CT revealed a right upper lobe mass, pleural effusion, and lymphadenopathy, prompting suspicion of malignancy.
Pejman Hosseinzadeh, Sara Samadi, Shirin Taraz Jamshidi, Sayed Mortaza Fayez, Mahnaz Mozdourian   +4 more
wiley   +1 more source

Tuberculosis control interventions targeted to previously treated people in a high-incidence setting: a modelling study

The Lancet Global Health, 2018
Summary: Background: In high-incidence settings, recurrent disease among previously treated individuals contributes substantially to the burden of incident and prevalent tuberculosis.
Florian M Marx, MD, Reza Yaesoubi, PhD, Nicolas A Menzies, PhD, Joshua A Salomon, PhD, Alyssa Bilinski, Nulda Beyers, PhD, Ted Cohen, MD   +6 more
doaj   +1 more source

Should TNF inhibitors be avoided in psoriasis patients with latent tuberculosis?

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Fabià Torres‐Betato, Lluís Puig
wiley   +1 more source

Tuberculosis in Sudan: A Comprehensive Narrative Review of Epidemiological Trends, Diagnosis, Drug Resistance, Challenges, and Data Gaps

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims This narrative review aims to provide a comprehensive overview of tuberculosis (TB) in Sudan, focusing on prevalence, drug resistance patterns, and associated challenges while identifying knowledge gaps in scientific research and data needed for effective management.
Mohammad Azhar Kamal, Hisham N. Altayb, Shima M. Abdulgader, Ehssan Moglad   +3 more
wiley   +1 more source