Results 61 to 70 of about 2,755,321 (217)

Understanding Barriers to Uptake of TB Preventive Treatment Among People Living with HIV in Zimbabwe: A Qualitative Assessment of Healthcare Workers’ Perspectives

Tropical Medicine and Infectious Disease
People living with HIV (PLHIV) are at an increased risk of progressing from Mycobacterium tuberculosis (TB) infection to TB disease. Tuberculosis preventive treatment (TPT) is recommended for PLHIV; however, its uptake remains suboptimal.
Tawanda Mapuranga, Collins Timire, Ronald T. Ncube, Sithabiso Dube, Nqobile Mlilo, Cynthia Chiteve, Owen Mugurungi, Tsitsi Mutasa-Apollo, Fungai Kavenga, Clorata Gwanzura, Manners Ncube, Nicholas Siziba, Selma Dar Berger, Talent Maphosa, Macarthur Charles, Riitta A. Dlodlo, Julia Ershova   +16 more
doaj   +1 more source

Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access

Clinical Pharmacology &Therapeutics, EarlyView.
Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian, Moherndran Archary, Daniel B. Hawcutt, Rachel Daley, Edmund Capparelli, Adeniyi Olagunju   +5 more
wiley   +1 more source

Management of children exposed to Mycobacterium tuberculosis: a public health evaluation in West Java, Indonesia

Bulletin of the World Health Organization, 2013
Objective To investigate qualitatively and quantitatively the performance of a programme for managing the child contacts of adult tuberculosis patients in Indonesia.
Merrin E Rutherford, Rovina Ruslami, Melissa Anselmo, Bachti Alisjahbana, Neti Yulianti, Hedy Sampurno, Reinout van Crevel, Philip C Hill   +7 more
doaj   +1 more source

Assessment of Barriers in Initiation and Completion of Isoniazid Preventive Therapy among Household Child Con-tacts of Pulmonary TB Patients in Delhi: A Mixed Method Study

National Journal of Community Medicine, 2020
Background: Young children (aged < 6 years) in contact with Sputum positive TB adults are often infected with Mycobacterium tuberculosis and once infected are at higher risk of progression to TB disease than adults.
Faheem Ahmed, Tazean Zahoor Malik, Farzana Islam, Areeba Muzaffar   +3 more
doaj   +1 more source

Population Pharmacokinetics and Detection Times of Betamethasone After Intravenous, Intramuscular, and Intranasal Jet Administration of Betamethasone Sodium Phosphate in Horses

Drug Testing and Analysis, EarlyView.
Betamethasone concentrations in 20 horses from Japan and Germany following IV, IM, and INJ administration of betamethasone phosphate were analyzed using population pharmacokinetic modeling. For IV administration of 0.04 mg/kg q24 h, IPC and IUC were 0.012 and 0.31 ng/mL, respectively; the IUC approximated the IFHA urine ISL (0.20 ng/mL).
Taisuke Kuroda, Marc Machnik, Mario Thevis, Yohei Minamijima, Gary Ngai‐Wa Leung, Motoi Nomura, Fumiaki Mizobe, Yuhiro Ishikawa, Kazuhiro Kamiya, Pierre‐Louis Toutain   +9 more
wiley   +1 more source

The cost-effectiveness of tuberculosis preventive therapy for HIV-infected individuals in southern India: a trial-based analysis. [PDF]

PLoS ONE, 2012
Regimens for isoniazid-based preventive therapy (IPT) for tuberculosis (TB) in HIV-infected individuals have not been widely adopted given concerns regarding efficacy, adherence and drug resistance.
Mai T Pho, Soumya Swaminathan, Nagalingeswaran Kumarasamy, Elena Losina, C Ponnuraja, Lauren M Uhler, Callie A Scott, Kenneth H Mayer, Kenneth A Freedberg, Rochelle P Walensky   +9 more
doaj   +1 more source

The preventive therapy cascade.

, 2022
Abbreviations: TB—tuberculosis; HIV—human immunodeficiency virus; PLHIV- people living with HIV; IPT- isoniazid preventive therapy; CPT—cotrimoxazole preventive therapy.
Luís Velez Lapão (8589414), Pia Müller (586792)   +1 more
core   +1 more source

Risk factors for non-adherence to isoniazid preventive therapy.

, 2019
Risk factors for non-adherence to isoniazid preventive therapy.
Angèle Musabimana (6321209), Stephen Michael Graham (5620802), Francine Mwayuma Birungi (6321203), Jeannine Uwimana (6321206), Brian van Wyk (3079650)   +4 more
core   +1 more source

Tuberculosis control in a South African community with high HIV prevalence: the role of intensified case-finding and antiretroviral therapy [PDF]

This thesis investigates active TB case finding and antiretroviral therapy for tuberculosis control in a setting with high HIV prevalence in Cape Town, South Africa.
Kranzer, Katharina
core   +1 more source

Pediatric hereditary angioedema presenting as recurrent episodic abdominal pain and vomiting: Challenges in diagnosis and management

JPGN Reports, EarlyView.
Abstract Recurrent episodic abdominal pain and vomiting, with symptom‐free intervals between attacks, represent common and often challenging presentations in children, typically leading to extensive workups without a clear etiology, as standard diagnostic algorithms fail to include rare systemic conditions. We present the challenging diagnostic odyssey
Julio Nestor Busaniche, Jhoanna Valery Adauto Luizaga, Maria Soledad Arcucci, Claudio Alberto Salvador Parisi, Judith Cohen Sabban, Agustina Venditti, Valentina Riveros, Giancarlo Testa, Veronica Busoni   +8 more
wiley   +1 more source