Results 71 to 80 of about 18,433 (200)

Metabolism and Biological Activities of 4-Methyl-Sterols

Molecules, 2019
4,4-Dimethylsterols and 4-methylsterols are sterol biosynthetic intermediates (C4-SBIs) acting as precursors of cholesterol, ergosterol, and phytosterols.
Sylvain Darnet, Hubert Schaller
doaj   +1 more source

Concurrent Measurement of O2 Production and Isoprene Emission During Photosynthesis: Pros, Cons and Metabolic Implications of Responses to Light, CO2 and Temperature

Plant, Cell &Environment, EarlyView.
ABSTRACT Traditional leaf gas exchange experiments have focused on net CO2 exchange (Anet). Here, using California poplar (Populus trichocarpa), we coupled measurements of net oxygen production (NOP), isoprene emissions and δ18O in O2 to traditional CO2/H2O gas exchange with chlorophyll fluorescence, and measured light, CO2 and temperature response ...
Kolby Jeremiah Jardine, Suman Som, Luiza Beraldi Gallo, Jilian Demus, Tomas Ferreira Domingues, Christina Marie Wistrom, Lianhong Gu, Guillaume Tcherkez, Ülo Niinemets   +8 more
wiley   +1 more source

Diurnal Variations in Photochemical Energy Utilization and Osmotic Adjustments in Black Poplar Leaves Under Progressive Water Stress

Plant, Cell &Environment, EarlyView.
ABSTRACT Drought limits the productivity of fast‐growing woody crops, although the metabolic adjustments conferring water stress tolerance remain poorly understood. We investigated the responses of Populus nigra seedlings to water stress by integrating daily physiological measurements and NMR metabolomic analyses.
Antonella Gori, Mauro Centritto, Anatoly P. Sobolev, Giovanni Marino, Francesco Loreto, Francesca Alderotti, Cecilia Brunetti   +6 more
wiley   +1 more source

A Metabolic Dependency for Host Isoprenoids in the Obligate Intracellular Pathogen Rickettsia parkeri Underlies a Sensitivity to the Statin Class of Host-Targeted Therapeutics

mSphere, 2019
Gram-negative bacteria in the order Rickettsiales have an obligate intracellular growth requirement, and some species cause human diseases such as typhus and spotted fever.
Vida Ahyong, Charles A. Berdan, Thomas P. Burke, Daniel K. Nomura, Matthew D. Welch   +4 more
doaj   +1 more source

Isoprene‐Emitting Transgenic Tobacco Shapes Root Microbiome and Enhances Growth of Co‐Cultivated Non‐Emitting Plants

Plant, Cell &Environment, EarlyView.
ABSTRACT Isoprene is the most abundant biogenic volatile organic compound emitted by terrestrial vegetation. Here we report the impact of isoprene on root‐associated microbiomes. Using isoprene‐emitting (IE) transgenic tobacco and isogenic non‐emitting (NE) controls, we performed co‐cultivation experiments in natural soil and analysed plant phenotypes ...
Manuel Bellucci, Mohammad Golam Mostofa, Gian Maria Niccolò Benucci, Ahmad Humayan Kabir, Imran Khan, Marco Lombardi, Vittoria Locato, Gregory Bonito, Francesco Loreto, Thomas D. Sharkey   +9 more
wiley   +1 more source

Occurrence of squalene, di- and tetrahydrosqualenes, and vitamin MK8 in an extremely halophilic bacterium, Halobacterium cutirubrum

Journal of Lipid Research, 1969
The nonpolar (acetone-soluble) lipids of the extremely halophilic bacterium, Halobacterium cutirubrum, were found to consist of red carotenoid pigments (43%) and squalenes (48%) with a small amount of a vitamin K-type quinone. The squalenes were shown by
T.G. Tornabene, M. Kates, E. Gelpi, J. Oro   +3 more
doaj   +1 more source

The History of the Discovery of Vitamin K

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 3, September 2026.
ABSTRACT Vitamin K was discovered during the 1930s when a strange haemorrhagic disorder was observed in chickens fed a cholesterol‐free diet. A fat‐soluble agent, present in green leafy vegetables and hog liver, was able to restore haemostasis in the chickens.
Hanna Nørgaard Tuxen, Laila Zwisler, Allan Linneberg   +2 more
wiley   +1 more source

Functional characterization and evolution of the isotuberculosinol operon in Mycobacterium tuberculosis and related Mycobacteria

Frontiers in Microbiology, 2012
Terpenoid metabolites are important to the cellular function, structural integrity, and pathogenesis of the human-specific pathogen Mycobacterium tuberculosis (Mtb).
Reuben J Peters, Francis M Mann, Meimei eXu, Emily K Davenport   +3 more
doaj   +1 more source

Atorvastatin Reduces Alcohol‐Related Cardiac and Liver Tissue Damage, Oxidative Stress, Inflammation, Apoptosis, and Thiol‐Disulfide Imbalance in Rats

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Atorvastatin (40 mg/kg) inhibited fibrosis, hypertrophy, apoptosis, inflammation, and oxidative stress caused by alcohol consumption. It may contribute to the regulation of mitochondrial function and thiol/disulfide balance by limiting alcohol‐related heart and liver damage.
Cumaali Demirtas, Şahhan Kılıç, Mert Babaoğlu, Süha Asal, Elif Gökçe Tenekeci, Hakan Beyaztaş, Eray Metin Guler, Salime Pelin Erguven, Kubra Sevgin   +8 more
wiley   +1 more source

Antibiotic fosmidomycin protects bacteria from cell wall perturbations by antagonizing oxidative damage-mediated cell lysis

Frontiers in Microbiology
Cell wall peptidoglycan is a defining component of bacterial cells, and its biosynthesis is a major target for medically important antibiotics. Recent studies have revealed that antibiotics can kill cells not only by their direct effects on wall ...
Yoshikazu Kawai, Jeff Errington
doaj   +1 more source